 Epigenesis, Genetic
"Epigenesis, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A genetic process by which the adult organism is realized via mechanisms that lead to the restriction in the possible fates of cells, eventually leading to their differentiated state. Mechanisms involved cause heritable changes to cells without changes to DNA sequence such as DNA METHYLATION; HISTONE modification; DNA REPLICATION TIMING; NUCLEOSOME positioning; and heterochromatization which result in selective gene expression or repression.
| Descriptor ID |
D044127
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| MeSH Number(s) |
G05.355.315.203
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| Concept/Terms |
Epigenetic Processes- Epigenetic Processes
- Processes, Epigenetic
- Epigenetics Processes
- Processes, Epigenetics
- Epigenetic Process
- Process, Epigenetic
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Below are MeSH descriptors whose meaning is more general than "Epigenesis, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Epigenesis, Genetic".
This graph shows the total number of publications written about "Epigenesis, Genetic" by people in this website by year, and whether "Epigenesis, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 1 | 2 | | 2012 | 2 | 0 | 2 | | 2013 | 3 | 3 | 6 | | 2014 | 2 | 5 | 7 | | 2015 | 4 | 5 | 9 | | 2016 | 1 | 2 | 3 | | 2017 | 2 | 4 | 6 | | 2018 | 1 | 3 | 4 | | 2019 | 3 | 4 | 7 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 2 | 3 | | 2023 | 0 | 1 | 1 | | 2024 | 0 | 2 | 2 |
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Below are the most recent publications written about "Epigenesis, Genetic" by people in Profiles.
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Christiansen C, Potier L, Martin TC, Villica?a S, Castillo-Fernandez JE, Mangino M, Menni C, Tsai PC, Campbell PJ, Mullin S, Ordo?ana JR, Monteagudo O, Sachdev PS, Mather KA, Trollor JN, Pietilainen KH, Ollikainen M, Dalg?rd C, Kyvik K, Christensen K, van Dongen J, Willemsen G, Boomsma DI, Magnusson PKE, Pedersen NL, Wilson SG, Grundberg E, Spector TD, Bell JT. Enhanced resolution profiling in twins reveals differential methylation signatures of type 2 diabetes with links to its complications. EBioMedicine. 2024 May; 103:105096.
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Aracena KA, Lin YL, Luo K, Pacis A, Gona S, Mu Z, Yotova V, Sindeaux R, Pramatarova A, Simon MM, Chen X, Groza C, Lougheed D, Gregoire R, Brownlee D, Boye C, Pique-Regi R, Li Y, He X, Bujold D, Pastinen T, Bourque G, Barreiro LB. Epigenetic variation impacts individual differences in the transcriptional response to influenza infection. Nat Genet. 2024 Mar; 56(3):408-419.
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Fu Q, Frick JM, O'Neil MF, Eller OC, Morris EM, Thyfault JP, Christianson JA, Lane RH. Early-life stress perturbs the epigenetics of Cd36 concurrent with adult onset of NAFLD in mice. Pediatr Res. 2023 Dec; 94(6):1942-1950.
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Spector BL, Harrell L, Sante D, Wyckoff GJ, Willig L. The methylome and cell-free DNA: current applications in medicine and pediatric disease. Pediatr Res. 2023 07; 94(1):89-95.
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Ke X, Huang Y, Fu Q, Majnik A, Sampath V, Lane RH. Adverse maternal environment alters Oprl1 variant expression in mouse hippocampus. Anat Rec (Hoboken). 2023 01; 306(1):162-175.
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Christiansen C, Tomlinson M, Eliot M, Nilsson E, Costeira R, Xia Y, Villica?a S, Mompeo O, Wells P, Castillo-Fernandez J, Potier L, Vohl MC, Tchernof A, Moustafa JE, Menni C, Steves CJ, Kelsey K, Ling C, Grundberg E, Small KS, Bell JT. Adipose methylome integrative-omic analyses reveal genetic and dietary metabolic health drivers and insulin resistance classifiers. Genome Med. 2022 07 18; 14(1):75.
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Shao X, Le Stunff C, Cheung W, Kwan T, Lathrop M, Pastinen T, Bougn?res P. Differentially methylated CpGs in response to growth hormone administration in children with idiopathic short stature. Clin Epigenetics. 2022 05 18; 14(1):65.
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Ke X, Huang Y, Fu Q, Majnik A, Lane RH. Adverse maternal environment affects hippocampal HTR2c variant expression and epigenetic characteristics in mouse offspring. Pediatr Res. 2022 11; 92(5):1299-1308.
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Sweha SR, Chung C, Natarajan SK, Panwalkar P, Pun M, Ghali A, Bayliss J, Pratt D, Shankar A, Ravikumar V, Rao A, Cieslik M, Wilder-Romans K, Scott AJ, Wahl DR, Jessa S, Kleinman CL, Jabado N, Mackay A, Jones C, Martinez D, Santi M, Judkins AR, Yadav VN, Qin T, Phoenix TN, Koschmann CJ, Baker SJ, Chinnaiyan AM, Venneti S. Epigenetically defined therapeutic targeting in H3.3G34R/V high-grade gliomas. Sci Transl Med. 2021 Oct 13; 13(615):eabf7860.
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Ke X, Huang Y, Fu Q, Lane RH, Majnik A. Adverse Maternal Environment Alters MicroRNA-10b-5p Expression and Its Epigenetic Profile Concurrently with Impaired Hippocampal Neurogenesis in Male Mouse Hippocampus. Dev Neurosci. 2021; 43(2):95-105.
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