Loading...
Keywords
Last Name
Institution

Dolores Lamb, PhD

TitleDirector, Developmental Biology
InstitutionChildren's Mercy Kansas City
DepartmentPediatric
Address2401 Gilham Rd
Kansas City MO 64108
vCardDownload vCard
    Other Positions
    TitleCo-Director Research Learning Center
    InstitutionChildren's Mercy Kansas City
    DepartmentPediatric


    Collapse Biography 
    Collapse education and training
    Baylor College of Medicine, Houston, TXFellow1983Cell Biology
    The University of Texas Medical School, Houston, TXFellow1981Reproductive Biology
    Graduate School of Biomedical Sciences University of Texas Health Science Center at Houston, Houston, TXPh. D.1980
    Adelphi University , Garden City, NYMS1976
    Molloy College, Rockville Centre, NYBS1974

    Collapse Overview 

    Collapse Bibliography 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Vong KI, Lee S, Au KS, Crowley TB, Capra V, Martino J, Haller M, Ara?jo C, Machado HR, George R, Gerding B, James KN, Stanley V, Jiang N, Alu K, Meave N, Nidhiry AS, Jiwani F, Tang I, Nisal A, Jhamb I, Patel A, Patel A, McEvoy-Venneri J, Barrows C, Shen C, Ha YJ, Howarth R, Strain M, Ashley-Koch AE, Azam M, Mumtaz S, Bot GM, Finnell RH, Kibar Z, Marwan AI, Melikishvili G, Meltzer HS, Mutchinick OM, Stevenson DA, Mroczkowski HJ, Ostrander B, Schindewolf E, Moldenhauer J, Zackai EH, Emanuel BS, Garcia-Minaur S, Nowakowska BA, Stevenson RE, Zaki MS, Northrup H, McNamara HK, Aldinger KA, Phelps IG, Deng M, Glass IA, Morrow B, McDonald-McGinn DM, Sanna-Cherchi S, Lamb DJ, Gleeson JG. Risk of meningomyelocele mediated by the common 22q11.2 deletion. Science. 2024 05 03; 384(6695):584-590. PMID: 38696583.
      View in: PubMed
    2. Eisenberg ML, Esteves SC, Lamb DJ, Hotaling JM, Giwercman A, Hwang K, Cheng YS. Male infertility. Nat Rev Dis Primers. 2023 09 14; 9(1):49. PMID: 37709866.
      View in: PubMed
    3. Lamb DJ, Marinaro JA. Can semen parameters predict pregnancy outcomes? Fertil Steril. 2023 10; 120(4):709-714. PMID: 37414207.
      View in: PubMed
    4. Lamb DJ. Nowhere to hide? from endocrine-disrupting chemical exposures. Fertil Steril. 2023 Sep; 120(3 Pt 2):648-649. PMID: 37414205.
      View in: PubMed
    5. Ruthig VA, Lamb DJ. Modeling development of genitourinary birth defects to understand disruption due to changes in gene dosage. Am J Clin Exp Urol. 2022; 10(6):412-424. PMID: 36636694.
      View in: PubMed
    6. Seth A, Rivera A, Chahdi A, Choi IS, Medina-Martinez O, Lewis S, O'Neill M, Ridgeway A, Moore J, Jorgez C, Lamb DJ. Gene dosage changes in KCTD13 result in penile and testicular anomalies via diminished androgen receptor function. FASEB J. 2022 11; 36(11):e22567. PMID: 36196997.
      View in: PubMed
    7. Bj?rndahl L, Barratt CLR, Mortimer D, Agarwal A, Aitken RJ, Alvarez JG, Aneck-Hahn N, Arver S, Baldi E, Bassas L, Boitrelle F, Bornman R, Carrell DT, Castilla JA, Cerezo Parra G, Check JH, Cuasnicu PS, Darney SP, de Jager C, De Jonge CJ, Drevet JR, Drobnis EZ, Du Plessis SS, Eisenberg ML, Esteves SC, Evgeni EA, Ferlin A, Garrido N, Giwercman A, Goovaerts IGF, Haugen TB, Henkel R, Henningsohn L, Hofmann MC, Hotaling JM, Jedrzejczak P, Jouannet P, J?rgensen N, Kirkman Brown JC, Krausz C, Kurpisz M, Kvist U, Lamb DJ, Levine H, Loveland KL, McLachlan RI, Mahran A, Maree L, Martins da Silva S, Mbizvo MT, Meinhardt A, Menkveld R, Mortimer ST, Moskovtsev S, Muller CH, Munuce MJ, Muratori M, Niederberger C, O'Flaherty C, Oliva R, Ombelet W, Pacey AA, Palladino MA, Ramasamy R, Ramos L, Rives N, Roldan ER, Rothmann S, Sakkas D, Salonia A, S?nchez-Pozo MC, Sapiro R, Schlatt S, Schlegel PN, Schuppe HC, Shah R, Skakkeb?k NE, Teerds K, Toskin I, Tournaye H, Turek PJ, van der Horst G, Vazquez-Levin M, Wang C, Wetzels A, Zeginiadou T, Zini A. Standards in semen examination: publishing reproducible and reliable data based on high-quality methodology. Hum Reprod. 2022 10 31; 37(11):2497-2502. PMID: 36112046.
      View in: PubMed
    8. Punjani N, Kang C, Lamb DJ. Genetic Implications of Male-Reproductive-Health-Associated Comorbidities. Turk J Urol. 2022 Sep; 48(5):363-374. PMID: 36197143.
      View in: PubMed
    9. Ruthig VA, Lamb DJ. Updates in Sertoli Cell-Mediated Signaling During Spermatogenesis and Advances in Restoring Sertoli Cell Function. Front Endocrinol (Lausanne). 2022; 13:897196. PMID: 35600584.
      View in: PubMed
    10. Arora H, Qureshi R, Khodamoradi K, Seetharam D, Parmar M, Van Booven DJ, Issa IC, Sackstein R, Lamb D, Hare JM, Ramasamy R. Leptin secreted from testicular microenvironment modulates hedgehog signaling to augment the endogenous function of Leydig cells. Cell Death Dis. 2022 03 04; 13(3):208. PMID: 35246515.
      View in: PubMed
    11. Barratt CLR, Wang C, Baldi E, Toskin I, Kiarie J, Lamb DJ. What advances may the future bring to the diagnosis, treatment, and care of male sexual and reproductive health? Fertil Steril. 2022 02; 117(2):258-267. PMID: 35125173.
      View in: PubMed
    12. J?rgensen N, Lamb DJ, Levine H, Pastuszak AW, Sigalos JT, Swan SH, Eisenberg ML. Are worldwide sperm counts declining? Fertil Steril. 2021 12; 116(6):1457-1463. PMID: 34836581.
      View in: PubMed
    13. Punjani N, Kang C, Lamb DJ, Schlegel PN. Current updates and future perspectives in the evaluation of azoospermia: A systematic review. Arab J Urol. 2021; 19(3):206-214. PMID: 34552771.
      View in: PubMed
    14. Ramaswamy A, Pichs A, Klarich JV, Basourakos SP, Lee RK, Lamb DJ, Schaeffer EM, Hu JC. Influence of Department Leadership on Scholarly Productivity and Research Funding in Academic Urology. Urology. 2021 08; 154:136-140. PMID: 33482136.
      View in: PubMed
    15. Jorgez CJ, Seth A, Wilken N, Bournat JC, Chen CH, Lamb DJ. E2F1 regulates testicular descent and controls spermatogenesis by influencing WNT4 signaling. Development. 2021 01 13; 148(1). PMID: 33441379.
      View in: PubMed
    16. Schlegel PN, Sigman M, Collura B, De Jonge CJ, Eisenberg ML, Lamb DJ, Mulhall JP, Niederberger C, Sandlow JI, Sokol RZ, Spandorfer SD, Tanrikut C, Treadwell JR, Oristaglio JT, Zini A. Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline Part I. J Urol. 2021 Jan; 205(1):36-43. PMID: 33295257.
      View in: PubMed
    17. Schlegel PN, Sigman M, Collura B, De Jonge CJ, Eisenberg ML, Lamb DJ, Mulhall JP, Niederberger C, Sandlow JI, Sokol RZ, Spandorfer SD, Tanrikut C, Treadwell JR, Oristaglio JT, Zini A. Diagnosis and Treatment of Infertility in Men: AUA/ASRM Guideline PART II. J Urol. 2021 Jan; 205(1):44-51. PMID: 33295258.
      View in: PubMed
    18. Schlegel PN, Sigman M, Collura B, De Jonge CJ, Eisenberg ML, Lamb DJ, Mulhall JP, Niederberger C, Sandlow JI, Sokol RZ, Spandorfer SD, Tanrikut C, Treadwell JR, Oristaglio JT, Zini A. Diagnosis and treatment of infertility in men: AUA/ASRM guideline part II. Fertil Steril. 2021 01; 115(1):62-69. PMID: 33309061.
      View in: PubMed
    19. Schlegel PN, Sigman M, Collura B, De Jonge CJ, Eisenberg ML, Lamb DJ, Mulhall JP, Niederberger C, Sandlow JI, Sokol RZ, Spandorfer SD, Tanrikut C, Treadwell JR, Oristaglio JT, Zini A. Diagnosis and treatment of infertility in men: AUA/ASRM guideline part I. Fertil Steril. 2021 01; 115(1):54-61. PMID: 33309062.
      View in: PubMed
    20. Punjani N, Lamb DJ. Canary in the Coal Mine? Male Infertility as a Marker of Overall Health. Annu Rev Genet. 2020 11 23; 54:465-486. PMID: 33228412.
      View in: PubMed
    21. Punjani N, Kang C, Lamb DJ. Genetic implications of male-reproductive-health-associated comorbidities. Turk J Urol. 2020 Oct 30. PMID: 33201798.
      View in: PubMed
    22. Bekheirnia N, Glinton KE, Rossetti L, Manor J, Chen W, Lamb DJ, Braun MC, Bekheirnia MR. Clinical Utility of Genetic Testing in the Precision Diagnosis and Management of Pediatric Patients with Kidney and Urinary Tract Diseases. Kidney360. 2021 01 28; 2(1):90-104. PMID: 35368817.
      View in: PubMed
    23. Westfield G, Kaiser UB, Lamb DJ, Ramasamy R. Short-Acting Testosterone: More Physiologic? Front Endocrinol (Lausanne). 2020; 11:572465. PMID: 33117287.
      View in: PubMed
    24. Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M. The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 08 18; 13(8). PMID: 32571845.
      View in: PubMed
    25. Punjani N, Lamb DJ. Male infertility and genitourinary birth defects: there is more than meets the eye. Fertil Steril. 2020 08; 114(2):209-218. PMID: 32741459.
      View in: PubMed
    26. Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Al-Gazali L, Shamsi AMSMA, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR. Correction: DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract. Genet Med. 2020 Apr; 22(4):821. PMID: 31857706.
      View in: PubMed
    27. Lamb DJ. An approach that someday may boost testosterone biosynthesis in males with late-onset hypogonadism (low testosterone). Proc Natl Acad Sci U S A. 2019 11 12; 116(46):22904-22906. PMID: 31653760.
      View in: PubMed
    28. Shayota BJ, Le NT, Bekheirnia N, Rosenfeld JA, Goldstein AC, Moritz M, Bartholomew DW, Pastore MT, Xia F, Eng C, Yang Y, Lamb DJ, Scaglia F, Braun MC, Bekheirnia MR. Characterization of the renal phenotype in RMND1-related mitochondrial disease. Mol Genet Genomic Med. 2019 12; 7(12):e973. PMID: 31568715.
      View in: PubMed
    29. Blackburn ATM, Bekheirnia N, Uma VC, Corkins ME, Xu Y, Rosenfeld JA, Bainbridge MN, Yang Y, Liu P, Madan-Khetarpal S, Delgado MR, Hudgins L, Krantz I, Rodriguez-Buritica D, Wheeler PG, Al-Gazali L, Mohamed Saeed Mohamed Al Shamsi A, Gomez-Ospina N, Chao HT, Mirzaa GM, Scheuerle AE, Kukolich MK, Scaglia F, Eng C, Willsey HR, Braun MC, Lamb DJ, Miller RK, Bekheirnia MR. DYRK1A-related intellectual disability: a syndrome associated with congenital anomalies of the kidney and urinary tract. Genet Med. 2019 12; 21(12):2755-2764. PMID: 31263215.
      View in: PubMed
    30. Thirumavalavan N, Gabrielsen JS, Lamb DJ. Where are we going with gene screening for male infertility? Fertil Steril. 2019 05; 111(5):842-850. PMID: 31029238.
      View in: PubMed
    31. Pastuszak AW, Herati AS, Eisenberg ML, Cengiz C, Langlois PH, Kohn TP, Lamb DJ, Lipshultz LI. The risk of birth defects is not associated with semen parameters or mode of conception in offspring of men visiting a reproductive health clinic. Hum Reprod. 2019 04 01; 34(4):733-739. PMID: 30753581.
      View in: PubMed
    32. Halpern JA, Thirumavalavan N, Kohn TP, Patel AS, Leong JY, Cervellione RM, Keene DJB, Ibrahim E, Brackett NL, Lamb DJ, Ramasamy R. Distribution of Semen Parameters Among Adolescent Males Undergoing Fertility Preservation in a Multicenter International Cohort. Urology. 2019 05; 127:119-123. PMID: 30771377.
      View in: PubMed
    33. Arora H, Zuttion MSSR, Nahar B, Lamb D, Hare JM, Ramasamy R. Subcutaneous Leydig Stem Cell Autograft: A Promising Strategy to Increase Serum Testosterone. Stem Cells Transl Med. 2019 01; 8(1):58-65. PMID: 30280521.
      View in: PubMed
    34. Thirumavalavan N, Scovell JM, Link RE, Lamb DJ, Lipshultz LI. Does Solid Organ Transplantation Affect Male Reproduction? Eur Urol Focus. 2018 04; 4(3):307-310. PMID: 30194032.
      View in: PubMed
    35. Kohn TP, Kohn JR, Lamb DJ. Role of Sperm Morphology in Deciding Between Various Assisted Reproduction Technologies. Eur Urol Focus. 2018 04; 4(3):311-313. PMID: 30143470.
      View in: PubMed
    36. Gabrielsen JS, Lamb DJ, Lipshultz LI. Iron and a Man's Reproductive Health: the Good, the Bad, and the Ugly. Curr Urol Rep. 2018 Jun 01; 19(8):60. PMID: 29858708.
      View in: PubMed
    37. Haller M, Au J, O'Neill M, Lamb DJ. 16p11.2 transcription factor MAZ is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2018 02 20; 115(8):E1849-E1858. PMID: 29432158.
      View in: PubMed
    38. O'Neill M, Huang GO, Lamb DJ. Novel Application of Micro-Computerized Tomography for Morphologic Characterization of the Murine Penis. J Sex Med. 2017 12; 14(12):1533-1539. PMID: 29153581.
      View in: PubMed
    39. Barratt CLR, Bj?rndahl L, De Jonge CJ, Lamb DJ, Osorio Martini F, McLachlan R, Oates RD, van der Poel S, St John B, Sigman M, Sokol R, Tournaye H. The diagnosis of male infertility: an analysis of the evidence to support the development of global WHO guidance-challenges and future research opportunities. Hum Reprod Update. 2017 11 01; 23(6):660-680. PMID: 28981651.
      View in: PubMed
    40. Herati AS, Lamb DJ. Frontiers in sperm function testing: DNA fragmentation analysis shows promise. Transl Androl Urol. 2017 Sep; 6(Suppl 4):S457-S458. PMID: 29082161.
      View in: PubMed
    41. Haller M, Mo Q, Imamoto A, Lamb DJ. Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 05 09; 114(19):4981-4986. PMID: 28439006.
      View in: PubMed
    42. Herati AS, Zhelyazkova BH, Butler PR, Lamb DJ. Age-related alterations in the genetics and genomics of the male germ line. Fertil Steril. 2017 02; 107(2):319-323. PMID: 28160920.
      View in: PubMed
    43. Kovac JR, Smith RP, Cajipe M, Lamb DJ, Lipshultz LI. Men with a complete absence of normal sperm morphology exhibit high rates of success without assisted reproduction. Asian J Androl. 2017 Jan-Feb; 19(1):39-42. PMID: 27751992.
      View in: PubMed
    44. Pastuszak AW, Moon YM, Scovell J, Badal J, Lamb DJ, Link RE, Lipshultz LI. Poor Sleep Quality Predicts Hypogonadal Symptoms and Sexual Dysfunction in Male Nonstandard Shift Workers. Urology. 2017 04; 102:121-125. PMID: 27988267.
      View in: PubMed
    45. Bekheirnia MR, Bekheirnia N, Bainbridge MN, Gu S, Coban Akdemir ZH, Gambin T, Janzen NK, Jhangiani SN, Muzny DM, Michael M, Brewer ED, Elenberg E, Kale AS, Riley AA, Swartz SJ, Scott DA, Yang Y, Srivaths PR, Wenderfer SE, Bodurtha J, Applegate CD, Velinov M, Myers A, Borovik L, Craigen WJ, Hanchard NA, Rosenfeld JA, Lewis RA, Gonzales ET, Gibbs RA, Belmont JW, Roth DR, Eng C, Braun MC, Lupski JR, Lamb DJ. Whole-exome sequencing in the molecular diagnosis of individuals with congenital anomalies of the kidney and urinary tract and identification of a new causative gene. Genet Med. 2017 04; 19(4):412-420. PMID: 27657687.
      View in: PubMed
    46. Herati AS, Cengiz C, Lamb DJ. Assays of Serum Testosterone. Urol Clin North Am. 2016 May; 43(2):177-84. PMID: 27132574.
      View in: PubMed
    47. Song SH, Chiba K, Ramasamy R, Lamb DJ. Recent advances in the genetics of testicular failure. Asian J Androl. 2016 May-Jun; 18(3):350-5. PMID: 27048782.
      View in: PubMed
    48. Bianchi E, Boekelheide K, Sigman M, Lamb DJ, Hall SJ, Hwang K. Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-? Signaling Pathway. PLoS One. 2016; 11(4):e0153968. PMID: 27082244.
      View in: PubMed
    49. Chiba K, Ramasamy R, Lamb DJ, Lipshultz LI. The varicocele: diagnostic dilemmas, therapeutic challenges and future perspectives. Asian J Androl. 2016 Mar-Apr; 18(2):276-81. PMID: 26698233.
      View in: PubMed
    50. Pastuszak AW, Wenker EP, Smith PB, Abacan A, Lamb DJ, Lipshultz LI, Buzi R. Comprehensive Assessment of Health Needs of Young Minority Males Attending a Family Planning Clinic. Am J Mens Health. 2017 05; 11(3):542-551. PMID: 26846408.
      View in: PubMed
    51. Bianchi E, Boekelheide K, Sigman M, Lamb DJ, Hall SJ, Hwang K. Ghrelin ameliorates adhesions in a postsurgical mouse model. J Surg Res. 2016 Mar; 201(1):226-34. PMID: 26850207.
      View in: PubMed
    52. Kohn TP, Clavijo R, Ramasamy R, Hakky T, Candrashekar A, Lamb DJ, Lipshultz LI. Reproductive outcomes in men with karyotype abnormalities: Case report and review of the literature. Can Urol Assoc J. 2015 Sep-Oct; 9(9-10):E667-70. PMID: 26425238.
      View in: PubMed
    53. Pastuszak AW, Gomez LP, Scovell JM, Khera M, Lamb DJ, Lipshultz LI. Comparison of the Effects of Testosterone Gels, Injections, and Pellets on Serum Hormones, Erythrocytosis, Lipids, and Prostate-Specific Antigen. Sex Med. 2015 Sep; 3(3):165-73. PMID: 26468380.
      View in: PubMed
    54. Garcia JM, Chen JA, Guillory B, Donehower LA, Smith RG, Lamb DJ. Ghrelin Prevents Cisplatin-Induced Testicular Damage by Facilitating Repair of DNA Double Strand Breaks Through Activation of p53 in Mice. Biol Reprod. 2015 Jul; 93(1):24. PMID: 26019260.
      View in: PubMed
    55. Ramasamy R, Bakircioglu ME, Cengiz C, Karaca E, Scovell J, Jhangiani SN, Akdemir ZC, Bainbridge M, Yu Y, Huff C, Gibbs RA, Lupski JR, Lamb DJ. Whole-exome sequencing identifies novel homozygous mutation in NPAS2 in family with nonobstructive azoospermia. Fertil Steril. 2015 Aug; 104(2):286-91. PMID: 25956372.
      View in: PubMed
    56. Wenker EP, Dupree JM, Langille GM, Kovac J, Ramasamy R, Lamb D, Mills JN, Lipshultz LI. The Use of HCG-Based Combination Therapy for Recovery of Spermatogenesis after Testosterone Use. J Sex Med. 2015 Jun; 12(6):1334-7. PMID: 25904023.
      View in: PubMed
    57. Ramasamy R, Chiba K, Butler P, Lamb DJ. Male biological clock: a critical analysis of advanced paternal age. Fertil Steril. 2015 Jun; 103(6):1402-6. PMID: 25881878.
      View in: PubMed
    58. Scovell JM, Butler P, Ramasamy R, Lamb DJ. Words of wisdom. Re: Testosterone treatment is a potent tumor promoter for the rat prostate. Eur Urol. 2015 Apr; 67(4):814-5. PMID: 25765210.
      View in: PubMed
    59. Ramasamy R, Scovell JM, Kovac JR, Cook PJ, Lamb DJ, Lipshultz LI. Fluorescence in situ hybridization detects increased sperm aneuploidy in men with recurrent pregnancy loss. Fertil Steril. 2015 Apr; 103(4):906-909.e1. PMID: 25707335.
      View in: PubMed
    60. Whirledge SD, Garcia JM, Smith RG, Lamb DJ. Ghrelin partially protects against cisplatin-induced male murine gonadal toxicity in a GHSR-1a-dependent manner. Biol Reprod. 2015 Mar; 92(3):76. PMID: 25631345.
      View in: PubMed
    61. Gomez L, Kovac JR, Lamb DJ. CYP17A1 inhibitors in castration-resistant prostate cancer. Steroids. 2015 Mar; 95:80-7. PMID: 25560485.
      View in: PubMed
    62. Kovac JR, Kovac J, Pastuszak AW, Lamb DJ, Lipshultz LI. Testosterone supplementation therapy in the treatment of patients with metabolic syndrome. Postgrad Med. 2014 Nov; 126(7):149-56. PMID: 25387223.
      View in: PubMed
    63. Jorgez CJ, Wilken N, Addai JB, Newberg J, Vangapandu HV, Pastuszak AW, Mukherjee S, Rosenfeld JA, Lipshultz LI, Lamb DJ. Genomic and genetic variation in E2F transcription factor-1 in men with nonobstructive azoospermia. Fertil Steril. 2015 Jan; 103(1):44-52.e1. PMID: 25439843.
      View in: PubMed
    64. Ramasamy R, Besada S, Lamb DJ. Fluorescent in situ hybridization of human sperm: diagnostics, indications, and therapeutic implications. Fertil Steril. 2014 Dec; 102(6):1534-9. PMID: 25439797.
      View in: PubMed
    65. Eisenberg ML, Li S, Betts P, Herder D, Lamb DJ, Lipshultz LI. Testosterone therapy and cancer risk. BJU Int. 2015 Feb; 115(2):317-21. PMID: 24684569.
      View in: PubMed
    66. Jorgez CJ, Rosenfeld JA, Wilken NR, Vangapandu HV, Sahin A, Pham D, Carvalho CM, Bandholz A, Miller A, Weaver DD, Burton B, Babu D, Bamforth JS, Wilks T, Flynn DP, Roeder E, Patel A, Cheung SW, Lupski JR, Lamb DJ. Genitourinary defects associated with genomic deletions in 2p15 encompassing OTX1. PLoS One. 2014; 9(9):e107028. PMID: 25203062.
      View in: PubMed
    67. Kovac JR, Pan MM, Lipshultz LI, Lamb DJ. Current state of practice regarding testosterone supplementation therapy in men with prostate cancer. Steroids. 2014 Nov; 89:27-32. PMID: 25072793.
      View in: PubMed
    68. Ramasamy R, Ridgeway A, Lipshultz LI, Lamb DJ. Integrative DNA methylation and gene expression analysis identifies discoidin domain receptor 1 association with idiopathic nonobstructive azoospermia. Fertil Steril. 2014 Oct; 102(4):968-973.e3. PMID: 25064398.
      View in: PubMed
    69. Tannour-Louet M, Han S, Louet JF, Zhang B, Romero K, Addai J, Sahin A, Cheung SW, Lamb DJ. Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action. Nat Med. 2014 Jul; 20(7):715-24. PMID: 24880616.
      View in: PubMed
    70. Eisenberg ML, Li S, Behr B, Cullen MR, Galusha D, Lamb DJ, Lipshultz LI. Semen quality, infertility and mortality in the USA. Hum Reprod. 2014 Jul; 29(7):1567-74. PMID: 24838701.
      View in: PubMed
    71. Rickey LM, Yang CC, Lamb DJ. Women in Urology 2014. Urol Pract. 2014 Jul; 1(2):104-106. PMID: 37537799.
      View in: PubMed
    72. Kovac JR, Lamb DJ. Male infertility biomarkers and genomic aberrations in azoospermia. Fertil Steril. 2014 May; 101(5):e31. PMID: 24680367.
      View in: PubMed
    73. Sheehan MM, Ramasamy R, Lamb DJ. Molecular mechanisms involved in varicocele-associated infertility. J Assist Reprod Genet. 2014 May; 31(5):521-6. PMID: 24643631.
      View in: PubMed
    74. Jorgez CJ, Weedin JW, Sahin A, Tannour-Louet M, Han S, Bournat JC, Mielnik A, Cheung SW, Nangia A, Schlegel PN, Lipshultz LI, Lamb DJ. Y-chromosome microdeletions are not associated with SHOX haploinsufficiency. Hum Reprod. 2014 May; 29(5):1113-4. PMID: 24634249.
      View in: PubMed
    75. Ramasamy R, Lipshultz LI, Lamb DJ. Cancer risk among children born after assisted conception. N Engl J Med. 2014 03 06; 370(10):975. PMID: 24597876.
      View in: PubMed
    76. Kovac JR, Rajanahally S, Smith RP, Coward RM, Lamb DJ, Lipshultz LI. Patient satisfaction with testosterone replacement therapies: the reasons behind the choices. J Sex Med. 2014 Feb; 11(2):553-62. PMID: 24344902.
      View in: PubMed
    77. Tannour-Louet M, Lewis SK, Louet JF, Stewart J, Addai JB, Sahin A, Vangapandu HV, Lewis AL, Dittmar K, Pautler RG, Zhang L, Smith RG, Lamb DJ. Increased expression of CYP24A1 correlates with advanced stages of prostate cancer and can cause resistance to vitamin D3-based therapies. FASEB J. 2014 Jan; 28(1):364-72. PMID: 24081904.
      View in: PubMed
    78. Kovac JR, Addai J, Smith RP, Coward RM, Lamb DJ, Lipshultz LI. The effects of advanced paternal age on fertility. Asian J Androl. 2013 Nov; 15(6):723-8. PMID: 23912310.
      View in: PubMed
    79. Coward RM, Badhiwala NG, Kovac JR, Smith RP, Lamb DJ, Lipshultz LI. Impact of the 2012 American Urological Association vasectomy guidelines on post-vasectomy outcomes. J Urol. 2014 Jan; 191(1):169-74. PMID: 23917167.
      View in: PubMed
    80. Eisenberg ML, Betts P, Herder D, Lamb DJ, Lipshultz LI. Increased cancer risk and azoospermia. Fertil Steril. 2013 Sep; 100(3):e12. PMID: 23850299.
      View in: PubMed
    81. Eisenberg ML, Betts P, Herder D, Lamb DJ, Lipshultz LI. Increased risk of cancer among azoospermic men. Fertil Steril. 2013 Sep; 100(3):681-5. PMID: 23790640.
      View in: PubMed
    82. Kovac JR, Pastuszak AW, Lamb DJ. The use of genomics, proteomics, and metabolomics in identifying biomarkers of male infertility. Fertil Steril. 2013 Mar 15; 99(4):998-1007. PMID: 23415969.
      View in: PubMed
    83. Yatsenko AN, Georgiadis AP, Murthy LJ, Lamb DJ, Matzuk MM. UBE2B mRNA alterations are associated with severe oligozoospermia in infertile men. Mol Hum Reprod. 2013 Jun; 19(6):388-94. PMID: 23378580.
      View in: PubMed
    84. Pastuszak AW, Lamb DJ. Counting your sperm before they fertilize: are sperm counts really declining? Asian J Androl. 2013 Mar; 15(2):179-83. PMID: 23334199.
      View in: PubMed
    85. Eisenberg ML, Hsieh TC, Pastuszak AW, McIntyre MG, Walters RC, Lamb DJ, Lipshultz LI. The relationship between anogenital distance and the androgen receptor CAG repeat length. Asian J Androl. 2013 Mar; 15(2):286-9. PMID: 23334200.
      View in: PubMed
    86. Hwang K, Lamb DJ. The sperm penetration assay for the assessment of fertilization capacity. Methods Mol Biol. 2013; 927:103-11. PMID: 22992907.
      View in: PubMed
    87. Pastuszak AW, Lamb DJ. The genetics of male fertility--from basic science to clinical evaluation. J Androl. 2012 Nov-Dec; 33(6):1075-84. PMID: 22879527.
      View in: PubMed
    88. Eisenberg ML, Murthy L, Hwang K, Lamb DJ, Lipshultz LI. Sperm counts and sperm sex ratio in male infertility patients. Asian J Androl. 2012 Sep; 14(5):683-6. PMID: 22842703.
      View in: PubMed
    89. Hwang K, Lamb DJ. In vitro production of functional sperm in mice. Asian J Androl. 2011 Nov; 13(6):791-2. PMID: 21909122.
      View in: PubMed
    90. Yatsenko AN, O'Neil DS, Roy A, Arias-Mendoza PA, Chen R, Murthy LJ, Lamb DJ, Matzuk MM. Association of mutations in the zona pellucida binding protein 1 (ZPBP1) gene with abnormal sperm head morphology in infertile men. Mol Hum Reprod. 2012 Jan; 18(1):14-21. PMID: 21911476.
      View in: PubMed
    91. Weedin JW, Bennett RC, Fenig DM, Lamb DJ, Lipshultz LI. Early versus late maturation arrest: reproductive outcomes of testicular failure. J Urol. 2011 Aug; 186(2):621-6. PMID: 21684558.
      View in: PubMed
    92. Lamb DJ, Gibbons WE, Lobo RA, Rebar RW. Words of thanks to Dr. Alan H. DeCherney. Fertil Steril. 2011 Jun 30; 95(8):2437-8. PMID: 21704207.
      View in: PubMed
    93. Hwang K, Lamb DJ. Words of wisdom. Re: Testicular spermatozoa have statistically significantly lower DNA damage compared with ejaculated spermatozoa in patients with unsuccessful oral antioxidant treatment. Eur Urol. 2011 Apr; 59(4):657-8. PMID: 21414885.
      View in: PubMed
    94. Hwang K, Lipshultz LI, Lamb DJ. Use of diagnostic testing to detect infertility. Curr Urol Rep. 2011 Feb; 12(1):68-76. PMID: 21088937.
      View in: PubMed
    95. Jorgez CJ, Weedin JW, Sahin A, Tannour-Louet M, Han S, Bournat JC, Mielnik A, Cheung SW, Nangia AK, Schlegel PN, Lipshultz LI, Lamb DJ. Aberrations in pseudoautosomal regions (PARs) found in infertile men with Y-chromosome microdeletions. J Clin Endocrinol Metab. 2011 Apr; 96(4):E674-9. PMID: 21252244.
      View in: PubMed
    96. Hwang K, Lamb DJ. Diagnostic testicular biopsy before varicocele repair plays a realistic and important role. Fertil Steril. 2011 Feb; 95(2):488. PMID: 21183176.
      View in: PubMed
    97. Hwang K, Yatsenko AN, Jorgez CJ, Mukherjee S, Nalam RL, Matzuk MM, Lamb DJ. Mendelian genetics of male infertility. Ann N Y Acad Sci. 2010 Dec; 1214:E1-E17. PMID: 21382200.
      View in: PubMed
    98. Hwang K, Lamb DJ. New advances on the expansion and storage of human spermatogonial stem cells. Curr Opin Urol. 2010 Nov; 20(6):510-4. PMID: 20844436.
      View in: PubMed
    99. Mukherjee S, Ridgeway AD, Lamb DJ. DNA mismatch repair and infertility. Curr Opin Urol. 2010 Nov; 20(6):525-32. PMID: 20852424.
      View in: PubMed
    100. Tannour-Louet M, Han S, Corbett ST, Louet JF, Yatsenko S, Meyers L, Shaw CA, Kang SH, Cheung SW, Lamb DJ. Identification of de novo copy number variants associated with human disorders of sexual development. PLoS One. 2010 Oct 26; 5(10):e15392. PMID: 21048976.
      View in: PubMed
    101. Lamb DJ, Tannour-Louet M. In vivo exploration of the functional activity of the non-coding 8q24 prostate cancer risk locus. Asian J Androl. 2010 Nov; 12(6):787-9. PMID: 20818410.
      View in: PubMed
    102. Hwang K, Weedin JW, Lamb DJ. The use of fluorescent in situ hybridization in male infertility. Ther Adv Urol. 2010 Aug; 2(4):157-69. PMID: 21789092.
      View in: PubMed
    103. Hsieh MH, Hollander A, Lamb DJ, Turek PJ. The genetic and phenotypic basis of infertility in men with pediatric urologic disorders. Urology. 2010 Jul; 76(1):25-31. PMID: 20451977.
      View in: PubMed
    104. Yatsenko AN, Yatsenko SA, Weedin JW, Lawrence AE, Patel A, Peacock S, Matzuk MM, Lamb DJ, Cheung SW, Lipshultz LI. Comprehensive 5-year study of cytogenetic aberrations in 668 infertile men. J Urol. 2010 Apr; 183(4):1636-42. PMID: 20172548.
      View in: PubMed
    105. Hwang K, Lamb DJ. Words of wisdom. Re: Fertility preservation in adolescent males: experience over 22 years at Rouen University Hospital. Eur Urol. 2010 Jan; 57(1):173-4. PMID: 20178731.
      View in: PubMed
    106. Lamb DJ. Semen analysis in 21st century medicine: the need for sperm function testing. Asian J Androl. 2010 Jan; 12(1):64-70. PMID: 20111083.
      View in: PubMed
    107. Feng S, Ferlin A, Truong A, Bathgate R, Wade JD, Corbett S, Han S, Tannour-Louet M, Lamb DJ, Foresta C, Agoulnik AI. INSL3/RXFP2 signaling in testicular descent. Ann N Y Acad Sci. 2009 Apr; 1160:197-204. PMID: 19416188.
      View in: PubMed
    108. Turek P, Burnett A, Sigman M, Perreault S, Cornwall G, Chau K, Smith J, Prins G, Trasler J, Walsh T, Lamb D. 2008 Annual Meeting of the American Society of Andrology. Meeting summary. J Androl. 2009 May-Jun; 30(3):e2-9. PMID: 19269933.
      View in: PubMed
    109. Khera M, Grober ED, Najari B, Colen JS, Mohamed O, Lamb DJ, Lipshultz LI. Testosterone replacement therapy following radical prostatectomy. J Sex Med. 2009 Apr; 6(4):1165-1170. PMID: 19207277.
      View in: PubMed
    110. Matzuk MM, Lamb DJ. The biology of infertility: research advances and clinical challenges. Nat Med. 2008 Nov; 14(11):1197-213. PMID: 18989307.
      View in: PubMed
    111. Lamb DJ. Would gene therapy for the treatment of male infertility be safe? Nat Clin Pract Urol. 2008 Nov; 5(11):594-5. PMID: 18852705.
      View in: PubMed
    112. Shariat SF, Roehrborn CG, Lamb DJ, Slawin KM. Notice of duplicate publication: "Potentially harmful effect of a testosterone dietary supplement on prostate cancer growth and metastasis" (arch intern med. 2008;168[2]:235-236). Arch Intern Med. 2008 10 13; 168(18):2046-7. PMID: 18852410.
      View in: PubMed
    113. Alukal JP, Lamb DJ. Intracytoplasmic sperm injection (ICSI)--what are the risks? Urol Clin North Am. 2008 May; 35(2):277-88, ix-x. PMID: 18423248.
      View in: PubMed
    114. Shariat SF, Lamb DJ, Roehrborn CG, Slawin KM. Potentially harmful effect of a testosterone dietary supplement on prostate cancer growth and metastasis. Arch Intern Med. 2008 Jan 28; 168(2):235-6. PMID: 18227373.
      View in: PubMed
    115. Shariat SF, Lamb DJ, Iyengar RG, Roehrborn CG, Slawin KM. Herbal/hormonal dietary supplement possibly associated with prostate cancer progression. Clin Cancer Res. 2008 Jan 15; 14(2):607-11. PMID: 18223237.
      View in: PubMed
    116. Lamb DJ. When the quest for truth falters: the issue of scientific misconduct. J Urol. 2008 Jan; 179(1):11-2. PMID: 17997428.
      View in: PubMed
    117. Lipshultz LI, Lamb DJ. Risk of transmission of genetic diseases by assisted reproduction. Nat Clin Pract Urol. 2007 Sep; 4(9):460-1. PMID: 17684507.
      View in: PubMed
    118. Alukal JP, Lamb DJ. Words of wisdom. Re: Persistent motile sperm after ligation band vasectomy. Eur Urol. 2007 Aug; 52(2):606-7. PMID: 17674441.
      View in: PubMed
    119. Yatsenko AN, Roy A, Chen R, Ma L, Murthy LJ, Yan W, Lamb DJ, Matzuk MM. Non-invasive genetic diagnosis of male infertility using spermatozoal RNA: KLHL10 mutations in oligozoospermic patients impair homodimerization. Hum Mol Genet. 2006 Dec 01; 15(23):3411-9. PMID: 17047026.
      View in: PubMed
    120. Miyamato T, Sato H, Yogev L, Kleiman S, Namiki M, Koh E, Sakugawa N, Hayashi H, Ishikawa M, Lamb DJ, Sengoku K. Is a genetic defect in Fkbp6 a common cause of azoospermia in humans? Cell Mol Biol Lett. 2006; 11(4):557-69. PMID: 16983454.
      View in: PubMed
    121. Sato H, Miyamoto T, Yogev L, Namiki M, Koh E, Hayashi H, Sasaki Y, Ishikawa M, Lamb DJ, Matsumoto N, Birk OS, Niikawa N, Sengoku K. Polymorphic alleles of the human MEI1 gene are associated with human azoospermia by meiotic arrest. J Hum Genet. 2006; 51(6):533-540. PMID: 16683055.
      View in: PubMed
    122. Rohozinski J, Lamb DJ, Bishop CE. UTP14c is a recently acquired retrogene associated with spermatogenesis and fertility in man. Biol Reprod. 2006 Apr; 74(4):644-51. PMID: 16354793.
      View in: PubMed
    123. Lamb DJ, Zhang L. Challenges in prostate cancer research: animal models for nutritional studies of chemoprevention and disease progression. J Nutr. 2005 12; 135(12 Suppl):3009S-3015S. PMID: 16317162.
      View in: PubMed
    124. Lamb DJ, Zhang L, Buttyan R. A problem with a chaperone. J Urol. 2005 May; 173(5):1455. PMID: 15821459.
      View in: PubMed
    125. Shai S, Roudebush W, Powers D, Dirnfeld M, Lamb DJ. A multicenter study evaluating the flowcytometric-based kit for semen analysis. Fertil Steril. 2005 Apr; 83(4):1034-8. PMID: 15820817.
      View in: PubMed
    126. Falender AE, Freiman RN, Geles KG, Lo KC, Hwang K, Lamb DJ, Morris PL, Tjian R, Richards JS. Maintenance of spermatogenesis requires TAF4b, a gonad-specific subunit of TFIID. Genes Dev. 2005 Apr 01; 19(7):794-803. PMID: 15774719.
      View in: PubMed
    127. Lo KC, Whirledge S, Lamb DJ. Stem cells: implications for urology. Curr Urol Rep. 2005 Feb; 6(1):49-54. PMID: 15610697.
      View in: PubMed
    128. Lo KC, Brugh VM, Parker M, Lamb DJ. Isolation and enrichment of murine spermatogonial stem cells using rhodamine 123 mitochondrial dye. Biol Reprod. 2005 Mar; 72(3):767-71. PMID: 15576830.
      View in: PubMed
    129. McKenzie LJ, Kovanci E, Amato P, Cisneros P, Lamb D, Carson SA. Pregnancy outcome of in vitro fertilization/intracytoplasmic sperm injection with profound teratospermia. Fertil Steril. 2004 Oct; 82(4):847-9. PMID: 15482758.
      View in: PubMed
    130. Castro P, Xia C, Gomez L, Lamb DJ, Ittmann M. Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasia. Prostate. 2004 Jul 01; 60(2):153-9. PMID: 15162381.
      View in: PubMed
    131. King SR, Ginsberg SD, Ishii T, Smith RG, Parker KL, Lamb DJ. The steroidogenic acute regulatory protein is expressed in steroidogenic cells of the day-old brain. Endocrinology. 2004 Oct; 145(10):4775-80. PMID: 15205373.
      View in: PubMed
    132. Lo KC, Lei Z, Rao ChV, Beck J, Lamb DJ. De novo testosterone production in luteinizing hormone receptor knockout mice after transplantation of leydig stem cells. Endocrinology. 2004 Sep; 145(9):4011-5. PMID: 15123536.
      View in: PubMed
    133. Canto EI, Singh H, Shariat SF, Lamb DJ, Mikolajczyk SD, Linton HJ, Rittenhouse HG, Kadmon D, Miles BJ, Slawin KM. Serum BPSA outperforms both total PSA and free PSA as a predictor of prostatic enlargement in men without prostate cancer. Urology. 2004 May; 63(5):905-10; discussion 910-1. PMID: 15134977.
      View in: PubMed
    134. Shariat SF, Anwuri VA, Lamb DJ, Shah NV, Wheeler TM, Slawin KM. Association of preoperative plasma levels of vascular endothelial growth factor and soluble vascular cell adhesion molecule-1 with lymph node status and biochemical progression after radical prostatectomy. J Clin Oncol. 2004 May 01; 22(9):1655-63. PMID: 15117988.
      View in: PubMed
    135. Lo KC, Chuang WW, Lamb DJ. Stem cell research: the facts, the myths and the promises. J Urol. 2003 Dec; 170(6 Pt 1):2453-8. PMID: 14634449.
      View in: PubMed
    136. Miyamoto T, Hasuike S, Yogev L, Maduro MR, Ishikawa M, Westphal H, Lamb DJ. Azoospermia in patients heterozygous for a mutation in SYCP3. Lancet. 2003 Nov 22; 362(9397):1714-9. PMID: 14643120.
      View in: PubMed
    137. Maduro MR, Lo KC, Chuang WW, Lamb DJ. Genes and male infertility: what can go wrong? J Androl. 2003 Jul-Aug; 24(4):485-93. PMID: 12826685.
      View in: PubMed
    138. Castro P, Giri D, Lamb D, Ittmann M. Cellular senescence in the pathogenesis of benign prostatic hyperplasia. Prostate. 2003 Apr 01; 55(1):30-8. PMID: 12640658.
      View in: PubMed
    139. Lamb DJ, Puxeddu E, Malik N, Stenoien DL, Nigam R, Saleh GY, Mancini M, Weigel NL, Marcelli M. Molecular analysis of the androgen receptor in ten prostate cancer specimens obtained before and after androgen ablation. J Androl. 2003 Mar-Apr; 24(2):215-25. PMID: 12634308.
      View in: PubMed
    140. Brugh VM, Maduro MR, Lamb DJ. Genetic disorders and infertility. Urol Clin North Am. 2003 Feb; 30(1):143-52. PMID: 12580566.
      View in: PubMed
    141. Casella R, Maduro MR, Misfud A, Lipshultz LI, Yong EL, Lamb DJ. Androgen receptor gene polyglutamine length is associated with testicular histology in infertile patients. J Urol. 2003 Jan; 169(1):224-7. PMID: 12478141.
      View in: PubMed
    142. King SR, Manna PR, Ishii T, Syapin PJ, Ginsberg SD, Wilson K, Walsh LP, Parker KL, Stocco DM, Smith RG, Lamb DJ. An essential component in steroid synthesis, the steroidogenic acute regulatory protein, is expressed in discrete regions of the brain. J Neurosci. 2002 Dec 15; 22(24):10613-20. PMID: 12486153.
      View in: PubMed
    143. James AJ, Agoulnik IU, Harris JM, Buchanan G, Tilley WD, Marcelli M, Lamb DJ, Weigel NL. A novel androgen receptor mutant, A748T, exhibits hormone concentration-dependent defects in nuclear accumulation and activity despite normal hormone-binding affinity. Mol Endocrinol. 2002 Dec; 16(12):2692-705. PMID: 12456791.
      View in: PubMed
    144. Maduro MR, Lamb DJ. Understanding new genetics of male infertility. J Urol. 2002 Nov; 168(5):2197-205. PMID: 12394759.
      View in: PubMed
    145. Pagani R, Brugh VM, Lamb DJ. Y chromosome genes and male infertility. Urol Clin North Am. 2002 Nov; 29(4):745-53. PMID: 12516749.
      View in: PubMed
    146. Matzuk MM, Lamb DJ. Genetic dissection of mammalian fertility pathways. Nat Cell Biol. 2002 Oct; 4 Suppl:s41-9. PMID: 12479614.
      View in: PubMed
    147. Gorlov IP, Kamat A, Bogatcheva NV, Jones E, Lamb DJ, Truong A, Bishop CE, McElreavey K, Agoulnik AI. Mutations of the GREAT gene cause cryptorchidism. Hum Mol Genet. 2002 Sep 15; 11(19):2309-18. PMID: 12217959.
      View in: PubMed
    148. Maduro MR, Davis E, Davis A, Lamb DJ. Osteotesticular protein tyrosine phosphatase expression in rodent testis. J Urol. 2002 May; 167(5):2282-3. PMID: 11956493.
      View in: PubMed
    149. Shariat SF, Lamb DJ, Kattan MW, Nguyen C, Kim J, Beck J, Wheeler TM, Slawin KM. Association of preoperative plasma levels of insulin-like growth factor I and insulin-like growth factor binding proteins-2 and -3 with prostate cancer invasion, progression, and metastasis. J Clin Oncol. 2002 Feb 01; 20(3):833-41. PMID: 11821468.
      View in: PubMed
    150. Smith CL, DeVera DG, Lamb DJ, Nawaz Z, Jiang YH, Beaudet AL, O'Malley BW. Genetic ablation of the steroid receptor coactivator-ubiquitin ligase, E6-AP, results in tissue-selective steroid hormone resistance and defects in reproduction. Mol Cell Biol. 2002 Jan; 22(2):525-35. PMID: 11756548.
      View in: PubMed
    Lamb's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    See all (535) concept(s)
    _
    Similar People Expand Description
    See all (60) people
    _