 Cytochrome P-450 CYP1A1
"Cytochrome P-450 CYP1A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A liver microsomal cytochrome P-450 monooxygenase capable of biotransforming xenobiotics such as polycyclic hydrocarbons and halogenated aromatic hydrocarbons into carcinogenic or mutagenic compounds. They have been found in mammals and fish. This enzyme, encoded by CYP1A1 gene, can be measured by using ethoxyresorufin as a substrate for the ethoxyresorufin O-deethylase activity.
| Descriptor ID |
D019363
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| MeSH Number(s) |
D08.244.453.040.332 D08.811.682.690.708.170.040.332 D12.776.422.220.453.040.332
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| Concept/Terms |
Cytochrome P-450 CYP1A1- Cytochrome P-450 CYP1A1
- Cytochrome P 450 CYP1A1
- EROD
- Ethoxyresorufin Dealkylase
- CYP1A1 Protein
- CYP 1A1
- 7-Ethoxyresorufin O-Deethylase
- CYP1A1
- Cytochrome P450 IA1
- Ethoxyresorufin O-Deethylase
- Ethylresorufin O-Deethylase
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Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP1A1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP1A1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP1A1" by people in this website by year, and whether "Cytochrome P-450 CYP1A1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytochrome P-450 CYP1A1" by people in Profiles.
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Vyhlidal CA, Riffel AK, Haley KJ, Sharma S, Dai H, Tantisira KG, Weiss ST, Leeder JS. Cotinine in human placenta predicts induction of gene expression in fetal tissues. Drug Metab Dispos. 2013 Feb; 41(2):305-11.
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Goode EL, White KL, Vierkant RA, Phelan CM, Cunningham JM, Schildkraut JM, Berchuck A, Larson MC, Fridley BL, Olson JE, Webb PM, Chen X, Beesley J, Chenevix-Trench G, Sellers TA. Xenobiotic-Metabolizing gene polymorphisms and ovarian cancer risk. Mol Carcinog. 2011 May; 50(5):397-402.
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Graham MJ, Lucier GW, Linko P, Maronpot RR, Goldstein JA. Increases in cytochrome P-450 mediated 17 beta-estradiol 2-hydroxylase activity in rat liver microsomes after both acute administration and subchronic administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin in a two-stage hepatocarcinogenesis model. Carcinogenesis. 1988 Nov; 9(11):1935-41.
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