 Pharmacokinetics
"Pharmacokinetics" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Dynamic and kinetic mechanisms of exogenous chemical and DRUG LIBERATION; ABSORPTION; BIOLOGICAL TRANSPORT; TISSUE DISTRIBUTION; BIOTRANSFORMATION; elimination; and DRUG TOXICITY as a function of dosage, and rate of METABOLISM. LADMER, ADME and ADMET are abbreviations for liberation, absorption, distribution, metabolism, elimination, and toxicology.
| Descriptor ID |
D010599
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| MeSH Number(s) |
G03.787 G07.690.725
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Pharmacokinetics".
Below are MeSH descriptors whose meaning is more specific than "Pharmacokinetics".
This graph shows the total number of publications written about "Pharmacokinetics" by people in this website by year, and whether "Pharmacokinetics" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 2 | 0 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pharmacokinetics" by people in Profiles.
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Le J, Ramsey LB. Enhancing pharmacokinetic and pharmacodynamic knowledge in pediatrics. Pharmacotherapy. 2023 07; 43(7):578.
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Leeder JS, Dinh JC, Gaedigk A, Staggs VS, Prasad B, Pearce RE. Ontogeny of Scaling Factors for Pediatric Physiology-Based Pharmacokinetic Modeling and Simulation: Microsomal Protein Per Gram of Liver. Drug Metab Dispos. 2022 01; 50(1):24-32.
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Chapron BD, Chapron A, Leeder JS. Recent advances in the ontogeny of drug disposition. Br J Clin Pharmacol. 2022 10; 88(10):4267-4284.
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Lewis T. Precision therapeutics in the NICU: why are we missing the mark? J Perinatol. 2018 05; 38(5):444-446.
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Sandritter TL, McLaughlin M, Artman M, Lowry J. The Interplay between Pharmacokinetics and Pharmacodynamics. Pediatr Rev. 2017 May; 38(5):195-206.
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Leeder JS, Meibohm B. Challenges and Opportunities for Increasing the Knowledge Base Related to Drug Biotransformation and Pharmacokinetics during Growth and Development. Drug Metab Dispos. 2016 07; 44(7):916-23.
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Abdel-Rahman SM, Casey KL, Garg U, Dalal J. Intravenous busulfan dose individualization - impact of modeling approach on dose recommendation. Pediatr Transplant. 2016 May; 20(3):443-8.
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Brouwer KL, Aleksunes LM, Brandys B, Giacoia GP, Knipp G, Lukacova V, Meibohm B, Nigam SK, Rieder M, de Wildt SN. Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group. Clin Pharmacol Ther. 2015 Sep; 98(3):266-87.
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de Wildt SN, Tibboel D, Leeder JS. Drug metabolism for the paediatrician. Arch Dis Child. 2014 Dec; 99(12):1137-42.
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Leeder JS, Brown JT, Soden SE. Individualizing the use of medications in children: making Goldilocks happy. Clin Pharmacol Ther. 2014 Sep; 96(3):304-6.
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