 Proto-Oncogene Proteins c-crk
"Proto-Oncogene Proteins c-crk" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signal transducing adaptor proteins that contain SRC HOMOLOGY DOMAINS and play a role in CYTOSKELETON reorganization. c-crk protein is closely related to ONCOGENE PROTEIN V-CRK and includes several alternatively spliced isoforms.
| Descriptor ID |
D050737
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| MeSH Number(s) |
D12.644.360.024.318 D12.776.157.057.139 D12.776.476.024.409 D12.776.624.664.700.174
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| Concept/Terms |
Proto-Oncogene Proteins c-crk- Proto-Oncogene Proteins c-crk
- Proteins c-crk, Proto-Oncogene
- Proto Oncogene Proteins c crk
- c-crk, Proto-Oncogene Proteins
- Proto-Oncogene Protein c-crk
- Proto Oncogene Protein c crk
- c-crk, Proto-Oncogene Protein
- crk Proto-Oncogene Proteins
- Proto-Oncogene Proteins, crk
- crk Proto Oncogene Proteins
- CT10 Regulator of Kinase Protein
- c-crk Protein
- c-crk Proto-Oncogene Proteins
- Proto-Oncogene Proteins, c-crk
- c crk Proto Oncogene Proteins
Proto-Oncogene Protein c-crk-2- Proto-Oncogene Protein c-crk-2
- Proto Oncogene Protein c crk 2
- c-crk-2, Proto-Oncogene Protein
- CRKII Protein
- Crk-2 Protein
- Crk 2 Protein
- CrkII Adapter Protein
- Adapter Protein, CrkII
- c-crk-2 Proto-Oncogene Protein
- Proto-Oncogene Protein, c-crk-2
- c crk 2 Proto Oncogene Protein
- c-CrkII Protein
- c CrkII Protein
Proto-Oncogene Protein c-crk-3- Proto-Oncogene Protein c-crk-3
- Proto Oncogene Protein c crk 3
- c-crk-3, Proto-Oncogene Protein
- CrkIII Protein
- Crk3 Protein
- c-crk-3 Proto-Oncogene Protein
- Proto-Oncogene Protein, c-crk-3
- c crk 3 Proto Oncogene Protein
- c-CrkIII Protein
- c CrkIII Protein
Proto-Oncogene Protein c-crk-1- Proto-Oncogene Protein c-crk-1
- Proto Oncogene Protein c crk 1
- c-crk-1, Proto-Oncogene Protein
- CRKI Protein
- Crk-1 Protein
- Crk 1 Protein
- c-crk-I Proto-Oncogene Protein
- Proto-Oncogene Protein, c-crk-I
- c crk I Proto Oncogene Protein
- c-crkI Protein
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-crk".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-crk".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-crk" by people in this website by year, and whether "Proto-Oncogene Proteins c-crk" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 | | 2014 | 1 | 1 | 2 | | 2015 | 2 | 0 | 2 | | 2016 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 2 | 0 | 2 | | 2022 | 0 | 1 | 1 | | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-crk" by people in Profiles.
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Douglas JT, Johnson DK, Roy A, Park T. Use of phosphotyrosine-containing peptides to target SH2 domains: Antagonist peptides of the Crk/CrkL-p130Cas axis. Methods Enzymol. 2024; 698:301-342.
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Shi L, Racedo SE, Diacou A, Park T, Zhou B, Morrow BE. Crk and Crkl have shared functions in neural crest cells for cardiac outflow tract septation and vascular smooth muscle differentiation. Hum Mol Genet. 2022 04 22; 31(8):1197-1215.
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Park T. Crk and CrkL as Therapeutic Targets for Cancer Treatment. Cells. 2021 03 27; 10(4).
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Park T, Large N, Curran T. Quantitative assessment of glioblastoma phenotypes in?vitro establishes cell migration as a robust readout of Crk and CrkL activity. J Biol Chem. 2021 Jan-Jun; 296:100390.
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Park T, Curran T. Requirement for Crk and CrkL during postnatal lens development. Biochem Biophys Res Commun. 2020 08 27; 529(3):603-607.
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Nabekura T, Chen Z, Schroeder C, Park T, Vivier E, Lanier LL, Liu D. Crk Adaptor Proteins Regulate NK Cell Expansion and Differentiation during Mouse Cytomegalovirus Infection. J Immunol. 2018 05 15; 200(10):3420-3428.
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Collins TN, Mao Y, Li H, Bouaziz M, Hong A, Feng GS, Wang F, Quilliam LA, Chen L, Park T, Curran T, Zhang X. Crk proteins transduce FGF signaling to promote lens fiber cell elongation. Elife. 2018 01 23; 7.
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Park T, Koptyra M, Curran T. Fibroblast Growth Requires CT10 Regulator of Kinase (Crk) and Crk-like (CrkL). J Biol Chem. 2016 Dec 16; 291(51):26273-26290.
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Huang Y, Clarke F, Karimi M, Roy NH, Williamson EK, Okumura M, Mochizuki K, Chen EJ, Park TJ, Debes GF, Zhang Y, Curran T, Kambayashi T, Burkhardt JK. CRK proteins selectively regulate T cell migration into inflamed tissues. J Clin Invest. 2015 Mar 02; 125(3):1019-32.
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Koptyra M, Park TJ, Curran T. Crk and CrkL are required for cell transformation by v-fos and v-ras. Mol Carcinog. 2016 Jan; 55(1):97-104.
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