 Proto-Oncogene Proteins c-jun
"Proto-Oncogene Proteins c-jun" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun.
| Descriptor ID |
D016755
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| MeSH Number(s) |
D12.776.260.108.820 D12.776.624.664.700.182 D12.776.660.763 D12.776.930.127.820
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| Concept/Terms |
Proto-Oncogene Proteins c-jun- Proto-Oncogene Proteins c-jun
- Proto Oncogene Proteins c jun
- c-jun Proteins
- c jun Proteins
- fos-Associated Protein p39
- fos Associated Protein p39
- jun Proto-Oncogene Product p39
- jun Proto Oncogene Product p39
- jun Proto-Oncogene Proteins
- jun Proto Oncogene Proteins
- p39 c-jun
- p39 c jun
- p39(c-jun)
- Proto-Oncogene Products c-jun
- Proto Oncogene Products c jun
- c-fos-Associated Protein p39
- c fos Associated Protein p39
- Proto-Oncogene Proteins jun
- Proto Oncogene Proteins jun
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-jun".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-jun".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-jun" by people in this website by year, and whether "Proto-Oncogene Proteins c-jun" was a major or minor topic of these publications.
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Below are the most recent publications written about "Proto-Oncogene Proteins c-jun" by people in Profiles.
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Ordway JM, Eberhart D, Curran T. Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding. Mol Cell Biol. 2003 Jun; 23(12):4257-66.
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Kerppola TK, Curran T. The transcription activation domains of Fos and Jun induce DNA bending through electrostatic interactions. EMBO J. 1997 May 15; 16(10):2907-16.
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Ito K, Asano M, Hughes P, Kohzaki H, Masutani C, Hanaoka F, Kerppola T, Curran T, Murakami Y, Ito Y. c-Jun stimulates origin-dependent DNA unwinding by polyomavirus large Tantigen. EMBO J. 1996 Oct 15; 15(20):5636-46.
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Martin ML, Lieberman PM, Curran T. Fos-Jun dimerization promotes interaction of the basic region with TFIIE-34 and TFIIF. Mol Cell Biol. 1996 May; 16(5):2110-8.
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Hermida-Matsumoto ML, Chock PB, Curran T, Yang DC. Ubiquitinylation of transcription factors c-Jun and c-Fos using reconstituted ubiquitinylating enzymes. J Biol Chem. 1996 Mar 01; 271(9):4930-6.
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Kerppola T, Curran T. Transcription. Zen and the art of Fos and Jun. Nature. 1995 Jan 19; 373(6511):199-200.
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Soares HD, Curran T, Morgan JI. Transcription factors as molecular mediators in cell death. Ann N Y Acad Sci. 1994 Dec 15; 747:172-82.
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Kerppola TK, Curran T. A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nrl family proteins. Oncogene. 1994 Nov; 9(11):3149-58.
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Yaseen NR, Park J, Kerppola T, Curran T, Sharma S. A central role for Fos in human B- and T-cell NFAT (nuclear factor of activated T cells): an acidic region is required for in vitro assembly. Mol Cell Biol. 1994 Oct; 14(10):6886-95.
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Yao KS, Xanthoudakis S, Curran T, O'Dwyer PJ. Activation of AP-1 and of a nuclear redox factor, Ref-1, in the response of HT29 colon cancer cells to hypoxia. Mol Cell Biol. 1994 Sep; 14(9):5997-6003.
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