 Steroid 16-alpha-Hydroxylase
"Steroid 16-alpha-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A liver microsomal cytochrome P450 enzyme that catalyzes the 16-alpha-hydroxylation of a broad spectrum of steroids, fatty acids, and xenobiotics in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme is encoded by a number of genes from several CYP2 subfamilies.
| Descriptor ID |
D039181
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| MeSH Number(s) |
D08.244.453.915.737 D08.811.682.690.708.170.915.737 D12.776.422.220.453.915.737
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| Concept/Terms |
Steroid 16-alpha-Hydroxylase- Steroid 16-alpha-Hydroxylase
- 16-alpha-Hydroxylase, Steroid
- Steroid 16 alpha Hydroxylase
- 16alpha-Hydroxylase
- Estrogen 16-alpha Hydroxylase
- Estrogen 16 alpha Hydroxylase
- Estrone 16-alpha Hydroxylase
- Estrone 16 alpha Hydroxylase
- Estrone-3-sulfate 16-alpha Hydroxylase
- Estrone 3 sulfate 16 alpha Hydroxylase
- Progesterone 16-alpha-Hydroxylase
- Estradiol 16-alpha Hydroxylase
- Estradiol 16 alpha Hydroxylase
- Progesterone-16-alpha-Hydroxylase
- Progesterone 16 alpha-Hydroxylase
- Progesterone 16 alpha Hydroxylase
- Testosterone 16-alpha Hydroxylase
- Testosterone 16 alpha Hydroxylase
- Cytochrome P-450(16 alpha)
- Testosterone 16alpha Hydroxylase
- 16-alpha Hydroxylase
- 16 alpha Hydroxylase
- Steroid 16alpha-Hydroxylase
- Steroid 16alpha Hydroxylase
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Below are MeSH descriptors whose meaning is more general than "Steroid 16-alpha-Hydroxylase".
Below are MeSH descriptors whose meaning is more specific than "Steroid 16-alpha-Hydroxylase".
This graph shows the total number of publications written about "Steroid 16-alpha-Hydroxylase" by people in this website by year, and whether "Steroid 16-alpha-Hydroxylase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1998 | 2 | 0 | 2 | | 2001 | 3 | 0 | 3 |
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Below are the most recent publications written about "Steroid 16-alpha-Hydroxylase" by people in Profiles.
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Gaedigk A, Casley WL, Tyndale RF, Sellers EM, Jurima-Romet M, Leeder JS. Cytochrome P4502C9 (CYP2C9) allele frequencies in Canadian Native Indian and Inuit populations. Can J Physiol Pharmacol. 2001 Oct; 79(10):841-7.
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Kim JS, Nafziger AN, Gaedigk A, Dickmann LJ, Rettie AE, Bertino JS. Effects of oral vitamin K on S- and R-warfarin pharmacokinetics and pharmacodynamics: enhanced safety of warfarin as a CYP2C9 probe. J Clin Pharmacol. 2001 Jul; 41(7):715-22.
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Leeder JS. Pharmacogenetics and pharmacogenomics. Pediatr Clin North Am. 2001 Jun; 48(3):765-81.
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Henne KR, Gaedigk A, Gupta G, Leeder JS, Rettie AE. Chiral phase analysis of warfarin enantiomers in patient plasma in relation to CYP2C9 genotype. J Chromatogr B Biomed Sci Appl. 1998 Jun 12; 710(1-2):143-8.
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Blaisdell J, Goldstein JA, Bai SA. Isolation of a new canine cytochrome P450 CDNA from the cytochrome P450 2C subfamily (CYP2C41) and evidence for polymorphic differences in its expression. Drug Metab Dispos. 1998 Mar; 26(3):278-83.
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Ibeanu GC, Goldstein JA. Transcriptional regulation of human CYP2C genes: functional comparison of CYP2C9 and CYP2C18 promoter regions. Biochemistry. 1995 Jun 27; 34(25):8028-36.
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