 Sulfamethoxazole
"Sulfamethoxazole" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
| Descriptor ID |
D013420
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| MeSH Number(s) |
D02.065.884.725.867 D02.092.146.807.867 D02.886.590.700.725.867
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| Concept/Terms |
Sulfamethoxazole- Sulfamethoxazole
- Sulphamethoxazole
- Sulfamethylisoxazole
- Sulfisomezole
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Below are MeSH descriptors whose meaning is more general than "Sulfamethoxazole".
Below are MeSH descriptors whose meaning is more specific than "Sulfamethoxazole".
This graph shows the total number of publications written about "Sulfamethoxazole" by people in this website by year, and whether "Sulfamethoxazole" was a major or minor topic of these publications.
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Below are the most recent publications written about "Sulfamethoxazole" by people in Profiles.
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Cribb AE, Miller M, Leeder JS, Hill J, Spielberg SP. Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Implications for idiosyncratic toxicity. Drug Metab Dispos. 1991 Sep-Oct; 19(5):900-6.
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Leeder JS, Nakhooda A, Spielberg SP, Dosch HM. Cellular toxicity of sulfamethoxazole reactive metabolites--II. Inhibition of natural killer activity in human peripheral blood mononuclear cells. Biochem Pharmacol. 1991 Feb 15; 41(4):575-83.
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Leeder JS, Dosch HM, Spielberg SP. Cellular toxicity of sulfamethoxazole reactive metabolites--I. Inhibition of intracellular esterase activity prior to cell death. Biochem Pharmacol. 1991 Feb 15; 41(4):567-74.
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Riley RJ, Leeder JS, Dosch HM, Spielberg SP. Interactions between N-acetyl-p-benzoquinone imine and fluorescent calcium probes: implications for mechanistic toxicology. Anal Biochem. 1990 Dec; 191(2):253-61.
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Leeder JS, Dosch HM, Harper PA, Lam P, Spielberg SP. Fluorescence-based viability assay for studies of reactive drug intermediates. Anal Biochem. 1989 Mar; 177(2):364-72.
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