D013420Chemicals & DrugsD02.065.884.725.867D02.092.146.807.867D02.886.590.700.725.867150.998394Sulfamethoxazolecmhprofilesont:personsuffixperson suffixFaculty Rankprns:fullNamefull nameprns:hasAuthorListauthor listprns:hasFacultyRankhas faculty rankprns:hasNetworkhas networkprns:hasPublicationVenuepublished inprns:informationResourceReferenceinformation resource referenceprns:isPrimaryPositionis primary positionprns:latitudelatitudeprns:longitudelongitudeprns:mainImagephotoprns:maxWeightmaximum weightprns:medlineTAjournal title abbreviationprns:meshDescriptorUIMeSH DescriptorUIprns:meshSemanticGroupNameMeSH semantic group nameprns:meshTreeNumberMeSH tree numberprns:minWeightminimum weightprns:numberOfAuthorsnumber of authorsprns:numberOfConnectionsnumber of connectionsprns:numberOfPublicationsnumber of publicationsprns:personIdPerson IDprns:personInPrimaryPositionperson in primary positionprns:positionInDepartmentposition in departmentprns:positionInDivisionposition in divisionprns:predicateNodepredicate nodeprns:publicationDatepublication dateprns:sortOrdersort orderprns:uniquenessWeightuniqueness weightprns:yearyearAcademic ArticleArticleDocumentbibo:pmidPubMed IdentifierDepartmentDivisionvivo:hrJobTitleHR job titleInformation Resourcevivo:orcidIdORCID idPositionvivo:positionInOrganizationposition in organizationvivo:preferredTitlepreferred titlevivo:researchAreaOfresearch area ofvivo:subjectAreaForsubject area forrdf:predicatepredicaterdf:typetyperdfs:labellabelConceptAgentfoaf:firstNamefirst namefoaf:lastNamelast nameOrganizationPerson2085171Riley RJ, Leeder JS, Dosch HM, Spielberg SPAnalytical biochemistryRiley RJ, Leeder JS, Dosch HM, Spielberg SP. Interactions between N-acetyl-p-benzoquinone imine and fluorescent calcium probes: implications for mechanistic toxicology. Anal Biochem. 1990 Dec; 191(2):253-61.Anal Biochem1990-12-01T00:00:001990Interactions between N-acetyl-p-benzoquinone imine and fluorescent calcium probes: implications for mechanistic toxicology.2729556Leeder JS, Dosch HM, Harper PA, Lam P, Spielberg SPAnalytical biochemistryLeeder JS, Dosch HM, Harper PA, Lam P, Spielberg SP. Fluorescence-based viability assay for studies of reactive drug intermediates. Anal Biochem. 1989 Mar; 177(2):364-72.Anal Biochem1989-03-01T00:00:001989Fluorescence-based viability assay for studies of reactive drug intermediates.1686233Cribb AE, Miller M, Leeder JS, Hill J, Spielberg SPDrug metabolism and disposition: the biological fate of chemicalsCribb AE, Miller M, Leeder JS, Hill J, Spielberg SP. Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Implications for idiosyncratic toxicity. Drug Metab Dispos. 1991 Sep-Oct; 19(5):900-6.Drug Metab Dispos1991-09-01T00:00:001991Reactions of the nitroso and hydroxylamine metabolites of sulfamethoxazole with reduced glutathione. Implications for idiosyncratic toxicity.1997005Leeder JS, Dosch HM, Spielberg SPBiochemical pharmacologyLeeder JS, Dosch HM, Spielberg SP. Cellular toxicity of sulfamethoxazole reactive metabolites--I. Inhibition of intracellular esterase activity prior to cell death. Biochem Pharmacol. 1991 Feb 15; 41(4):567-74.Biochem Pharmacol1991-02-15T00:00:001991Cellular toxicity of sulfamethoxazole reactive metabolites--I. Inhibition of intracellular esterase activity prior to cell death.1997006Leeder JS, Nakhooda A, Spielberg SP, Dosch HMBiochemical pharmacologyLeeder JS, Nakhooda A, Spielberg SP, Dosch HM. Cellular toxicity of sulfamethoxazole reactive metabolites--II. Inhibition of natural killer activity in human peripheral blood mononuclear cells. Biochem Pharmacol. 1991 Feb 15; 41(4):575-83.Biochem Pharmacol1991-02-15T00:00:001991Cellular toxicity of sulfamethoxazole reactive metabolites--II. Inhibition of natural killer activity in human peripheral blood mononuclear cells.0.3214120.3214121research area of0.1046470.02483615subject area for1ProfessorPediatricsResearchPharmD, PhDJ. StevenLeederJ. Steven Leeder39.08346750000000-94.5771129000000034Leeder, J. Steven0000-0001-6688-0504Deputy Director, Children's Research InstituteChildren's Mercy Kansas Citytrue1Deputy Director, Children's Research InstituteDeputy Director, Children's Research Institute