 Proto-Oncogenes
"Proto-Oncogenes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Normal cellular genes homologous to viral oncogenes. The products of proto-oncogenes are important regulators of biological processes and appear to be involved in the events that serve to maintain the ordered procession through the cell cycle. Proto-oncogenes have names of the form c-onc.
| Descriptor ID |
D011519
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| MeSH Number(s) |
G05.360.340.024.340.375.500.791
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogenes".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogenes".
- Proto-Oncogenes
- Genes, abl
- Genes, bcl-1
- Genes, bcl-2
- Genes, erbA
- Genes, erbB
- Genes, fms
- Genes, fos
- Genes, jun
- Genes, mos
- Genes, myb
- Genes, myc
- Genes, ras
- Genes, rel
- Genes, sis
- Genes, src
This graph shows the total number of publications written about "Proto-Oncogenes" by people in this website by year, and whether "Proto-Oncogenes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogenes" by people in Profiles.
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Parnell SC, Raman A, Zhang Y, Daniel EA, Dai Y, Khanna A, Reif GA, Vivian JL, Fields TA, Wallace DP. Expression of active B-Raf proto-oncogene in kidney collecting ducts induces cyst formation in normal mice and accelerates cyst growth in mice with polycystic kidney disease. Kidney Int. 2022 11; 102(5):1103-1114.
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Ho PA, Alonzo TA, Gerbing RB, Pollard JA, Hirsch B, Raimondi SC, Cooper T, Gamis AS, Meshinchi S. High EVI1 expression is associated with MLL rearrangements and predicts decreased survival in paediatric acute myeloid leukaemia: a report from the children's oncology group. Br J Haematol. 2013 Sep; 162(5):670-7.
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Hayward MD, Curran T, Morgan JI. Immediate early genes: their involvement in physiological and pathological responses in the nervous system. NIDA Res Monogr. 1993; 125:39-53.
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Morgan JI, Curran T. Proto-oncogene transcription factors and epilepsy. Trends Pharmacol Sci. 1991 Sep; 12(9):343-9.
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Abate C, Luk D, Curran T. Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains. Mol Cell Biol. 1991 Jul; 11(7):3624-32.
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Morgan JI, Curran T. Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annu Rev Neurosci. 1991; 14:421-51.
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Owen TA, Bortell R, Yocum SA, Smock SL, Zhang M, Abate C, Shalhoub V, Aronin N, Wright KL, van Wijnen AJ, et al. Coordinate occupancy of AP-1 sites in the vitamin D-responsive and CCAAT box elements by Fos-Jun in the osteocalcin gene: model for phenotype suppression of transcription. Proc Natl Acad Sci U S A. 1990 Dec; 87(24):9990-4.
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Macgregor PF, Abate C, Curran T. Direct cloning of leucine zipper proteins: Jun binds cooperatively to the CRE with CRE-BP1. Oncogene. 1990 Apr; 5(4):451-8.
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Abate C, Luk D, Gentz R, Rauscher FJ, Curran T. Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly. Proc Natl Acad Sci U S A. 1990 Feb; 87(3):1032-6.
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Morgan JI, Curran T. Inducible proto-oncogenes of the nervous system: their contribution to transcription factors and neuroplasticity. Prog Brain Res. 1990; 86:287-94.
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