Genes, fos
"Genes, fos" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Retrovirus-associated DNA sequences (fos) originally isolated from the Finkel-Biskis-Jinkins (FBJ-MSV) and Finkel-Biskis-Reilly (FBR-MSV) murine sarcoma viruses. The proto-oncogene protein c-fos codes for a nuclear protein which is involved in growth-related transcriptional control. The insertion of c-fos into FBJ-MSV or FBR-MSV induces osteogenic sarcomas in mice. The human c-fos gene is located at 14q21-31 on the long arm of chromosome 14.
Descriptor ID |
D016762
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MeSH Number(s) |
G05.360.340.024.340.375.500.791.330
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Concept/Terms |
c-fos Genes- c-fos Genes
- c fos Genes
- c-fos Gene
- c-fos Proto-Oncogenes
- c fos Proto Oncogenes
- c-fos Proto-Oncogene
v-fos Genes- v-fos Genes
- v fos Genes
- v-fos Gene
- v-fos Oncogenes
- v fos Oncogenes
- v-fos Oncogene
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Below are MeSH descriptors whose meaning is more general than "Genes, fos".
Below are MeSH descriptors whose meaning is more specific than "Genes, fos".
This graph shows the total number of publications written about "Genes, fos" by people in this website by year, and whether "Genes, fos" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Genes, fos" by people in Profiles.
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Srivastava T, Heruth DP, Duncan RS, Rezaiekhaligh MH, Garola RE, Priya L, Zhou J, Boinpelly VC, Novak J, Ali MF, Joshi T, Alon US, Jiang Y, McCarthy ET, Savin VJ, Sharma R, Johnson ML, Sharma M. Transcription Factor ?-Catenin Plays a Key Role in Fluid Flow Shear Stress-Mediated Glomerular Injury in Solitary Kidney. Cells. 2021 05 19; 10(5).
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Ordway JM, Williams K, Curran T. Transcription repression in oncogenic transformation: common targets of epigenetic repression in cells transformed by Fos, Ras or Dnmt1. Oncogene. 2004 May 06; 23(21):3737-48.
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Bakin AV, Curran T. Role of DNA 5-methylcytosine transferase in cell transformation by fos. Science. 1999 Jan 15; 283(5400):387-90.
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Kasof GM, Mahanty NK, Pozzo Miller LD, Curran T, Connor JA, Morgan JI. Spontaneous and evoked glutamate signalling influences Fos-lacZ expression and pyramidal cell death in hippocampal slice cultures from transgenic rats. Brain Res Mol Brain Res. 1995 Dec 28; 34(2):197-208.
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Kasof GM, Mandelzys A, Maika SD, Hammer RE, Curran T, Morgan JI. Kainic acid-induced neuronal death is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats. J Neurosci. 1995 Jun; 15(6):4238-49.
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Curran T, Morgan JI. Fos: an immediate-early transcription factor in neurons. J Neurobiol. 1995 Mar; 26(3):403-12.
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Robertson LM, Kerppola TK, Vendrell M, Luk D, Smeyne RJ, Bocchiaro C, Morgan JI, Curran T. Regulation of c-fos expression in transgenic mice requires multiple interdependent transcription control elements. Neuron. 1995 Feb; 14(2):241-52.
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Miao GG, Curran T. Cell transformation by c-fos requires an extended period of expression and is independent of the cell cycle. Mol Cell Biol. 1994 Jun; 14(6):4295-310.
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Xanthoudakis S, Curran T. Analysis of c-Fos and c-Jun redox-dependent DNA binding activity. Methods Enzymol. 1994; 234:163-74.
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Molinar-Rode R, Smeyne RJ, Curran T, Morgan JI. Regulation of proto-oncogene expression in adult and developing lungs. Mol Cell Biol. 1993 Jun; 13(6):3213-20.
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