Loading...
Keywords
Last Name
Institution

Matthew J. McLaughlin, MD, MS

TitleRehabilitation Medicine Attending Physician
InstitutionChildren's Mercy Kansas City
DepartmentPediatrics
Address2401 Gillham Rd
Kansas City MO 64108
vCardDownload vCard
    Other Positions
    TitleAssistant Professor of Pediatrics
    InstitutionUniversity of Missouri-Kansas City
    DepartmentPediatrics

    TitleClinical Assistant Professor of Pediatrics
    InstitutionUniversity of Kansas Medical Center
    DepartmentPediatrics


    Collapse Biography 
    Collapse education and training
    University of Missouri-Kansas City School of Medicine, Kansas City, MOMD
    University of Missouri-Columbia Medical School, Columbia, MOResidencyPhysical Medicine/Rehabilitation
    Children's Mercy Hospital, Kansas City, MOFellowshipPediatric Physical Medicine/Rehabilitation
    University of Missouri-Kansas City School of Medicine, Kansas City, MOMS12/2015Bioinformatics
    Children's Mercy Hospital, Kansas City, MOFellowship09/2018Clinical Pharmacology
    Collapse awards and honors
    2018Best Original Research Paper by a Young Investigator, PM&R Journal
    2017Patient Experience Champion Award, Children’s Mercy Hospital
    2015Elite Manuscript Reviewer Award, Archives of Physical Medicine and Rehabilitation
    2015Vice Chancellor for Student Affairs and Enrollment Management Honor Recipient, University of Missouri-Kansas City

    Collapse Overview 

    Collapse Research 
    Collapse research overview
    Matt McLaughlin is a Pediatric Rehabilitation Medicine physician and Clinical Pharmacologist. His primary research centers on optimizing “the right medication for the right patient at the right time to improve outcomes.” He completed the MD/BA 6-year program at the University of Missouri-Kansas City prior to starting his fellowship at the University of Missouri-Columbia. After graduation from residency, he pursued a clinical Pediatric Rehabilitation Medicine fellowship at Children’s Mercy Hospital in Kansas City. During this time, he obtained his Masters in Medical Bioinformatics to help with clinical research design and database management. Upon graduation, he was named a Vice Chancellors Honors Recipient for obtaining a 4.0 GPA while also positively contributing to the Kansas City community. He received advance training in Clinical Pharmacology by participating in an NICHD T32 Fellowship in Pediatric Clinical and Developmental Pharmacology prior to starting his K12 funding.

    Dr. McLaughlin’s primary research work has centered around precision medicine in pediatric patients with cerebral palsy (CP). Clinically, he remains passionate about how to employ the pharmacogenetics associated with alterations in medication absorption, distribution, elimination and metabolism with improving clinical outcomes. He employs aspects of pharmacokinetic modeling, pharmacogenomics and clinical trial design in his studies. His work earned him the Best Original Research Article by a Young Physician by the PM&R Journal in 2018. He is currently an Assistant Professor in the Department of Pediatrics at Children’s Mercy – Kansas City.
    Collapse research activities and funding
    T32HD069038     (ABDEL-RAHMAN, SUSAN M)May 1, 2011 - Apr 30, 2021
    NIH/NICHD
    Children's Mercy Hospital Collaborative Fellowship Program in Pediatric Pharmacology
    Role: Co-Investigator

    U54HD090258     (LEEDER, JAMES STEVEN)Sep 23, 2016 - Jun 30, 2021
    NIH
    Genomic- and Ontogeny-Linked Dose Individualization and cLinical Optimization for Kids
    Role: Co-Investigator

    K12HD093427     (DROMERICK, ALEXANDER W)Aug 1, 2017 - Jul 31, 2022
    NIH
    Neurorehabilitation and Restorative Neuroscience Network
    Role: Co-Investigator

    Collapse Bibliography 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. McLaughlin MJ, Ratnasingam D, McGhee E. Variability of Steady State Oral Baclofen Prescribing Practices in Pediatric Patients With Cerebral Palsy. Am J Phys Med Rehabil. 2020 05; 99(5):441-443. PMID: 31688017.
      View in: PubMed
    2. He Q, Chhonker YS, McLaughlin MJ, Murry DJ. Simultaneous Quantitation of S(+)- and R(-)-Baclofen and Its Metabolite in Human Plasma and Cerebrospinal Fluid using LC-APCI-MS/MS: An Application for Clinical Studies. Molecules. 2020 Jan 08; 25(2). PMID: 31936209.
      View in: PubMed
    3. McLaughlin MJ, Wagner J, Shakhnovich V, Carleton B, Leeder JS. Considerations for Implementing Precision Therapeutics for Children. Clin Transl Sci. 2019 03; 12(2):140-150. PMID: 30516322.
      View in: PubMed
    4. McLaughlin M, Rahman S, Leeder JS. Examining the Role of Precision medicine with Oral Baclofen in Pediatric Patients with Cerebral Palsy. Current Physical Medicine and Rehabilitation Reports. 2019; 7(1):40-45.
    5. McLaughlin MJ, Abdel-Rahman S, Leeder JS. Examining the role of precision medicine with oral baclofen in pediatric patients with cerebral palsy. Curr Phys Med Rehabil Rep. 2019 Mar; 7(1):40-45. PMID: 31579558.
      View in: PubMed
    6. Weinstein SM, McLaughlin M. Ask the Authors. PM R. 2018 03; 10(3):243-244. PMID: 29127054.
      View in: PubMed
    7. McLaughlin MJ, He Y, Brunstrom-Hernandez J, Thio LL, Carleton BC, Ross CJD, Gaedigk A, Lewandowski A, Dai H, Jusko WJ, Leeder JS. Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy. PM R. 2018 03; 10(3):235-243. PMID: 28867665.
      View in: PubMed
    8. Sandritter TL, McLaughlin M, Artman M, Lowry J. The Interplay between Pharmacokinetics and Pharmacodynamics. Pediatr Rev. 2017 May; 38(5):195-206. PMID: 28461611.
      View in: PubMed
    9. McLaughlin M, Green M. Intradural spinal arteriovenous malformation in a 13-month-old female: A case report. J Pediatr Rehabil Med. 2015; 8(3):247-50. PMID: 26410067.
      View in: PubMed
    10. McLaughlin MJ, Sainani KL. Bonferroni, Holm, and Hochberg corrections: fun names, serious changes to p values. PM R. 2014 Jun; 6(6):544-6. PMID: 24769263.
      View in: PubMed
    McLaughlin's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    _
    Co-Authors Expand Description
    _
    Similar People Expand Description
    _
    Same Department Expand Description