Last Name

Matthew J. McLaughlin, MD, MS

TitleRehabilitation Medicine Attending Physician
InstitutionChildren's Mercy Kansas City
Address2401 Gillham Rd
Kansas City MO 64108
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    Other Positions
    TitleAssistant Professor of Pediatrics
    InstitutionUniversity of Missouri-Kansas City

    TitleClinical Assistant Professor of Pediatrics
    InstitutionUniversity of Kansas Medical Center

    Collapse Biography 
    Collapse education and training
    University of Missouri-Kansas City School of Medicine, Kansas City, MOMD
    University of Missouri-Columbia Medical School, Columbia, MOResidencyPhysical Medicine/Rehabilitation
    Children's Mercy Hospital, Kansas City, MOFellowshipPediatric Physical Medicine/Rehabilitation
    University of Missouri-Kansas City School of Medicine, Kansas City, MOMS12/2015Bioinformatics
    Children's Mercy Hospital, Kansas City, MOFellowship09/2018Clinical Pharmacology
    Collapse awards and honors
    2020Presidential Trainee Award, American Society for Clinical Pharmacology and Therapeutics
    2020Blue Ribbon for Top Poster, American Society for Clinical Pharmacology and Therapeutics
    2018Best Original Research Paper by a Young Investigator, PM&R Journal
    2017Patient Experience Champion Award, Children’s Mercy Hospital
    2015Elite Manuscript Reviewer Award, Archives of Physical Medicine and Rehabilitation
    2015Vice Chancellor for Student Affairs and Enrollment Management Honor Recipient, University of Missouri-Kansas City

    Collapse Overview 

    Collapse Research 
    Collapse research overview
    Matt McLaughlin is a Pediatric Rehabilitation Medicine physician and Clinical Pharmacologist. His primary research centers on optimizing “the right medication for the right patient at the right time to improve outcomes.” He completed the MD/BA 6-year program at the University of Missouri-Kansas City prior to starting his fellowship at the University of Missouri-Columbia. After graduation from residency, he pursued a clinical Pediatric Rehabilitation Medicine fellowship at Children’s Mercy Hospital in Kansas City. During this time, he obtained his Masters in Medical Bioinformatics to help with clinical research design and database management. Upon graduation, he was named a Vice Chancellors Honors Recipient for obtaining a 4.0 GPA while also positively contributing to the Kansas City community. He received advance training in Clinical Pharmacology by participating in an NICHD T32 Fellowship in Pediatric Clinical and Developmental Pharmacology prior to starting his K12 funding.

    Dr. McLaughlin’s primary research work has centered around precision medicine in pediatric patients with cerebral palsy (CP). Clinically, he remains passionate about how to employ the pharmacogenetics associated with alterations in medication absorption, distribution, elimination and metabolism with improving clinical outcomes. He employs aspects of pharmacokinetic modeling, pharmacogenomics and clinical trial design in his studies. His work earned him the Best Original Research Article by a Young Physician by the PM&R Journal in 2018. He is currently an Assistant Professor in the Department of Pediatrics at Children’s Mercy – Kansas City.
    Collapse research activities and funding
    T32HD069038     (ABDEL-RAHMAN, SUSAN M)May 1, 2011 - Mar 31, 2026
    Children's Mercy Hospital Collaborative Fellowship Program in Pediatric Pharmacology
    Role: Co-Investigator

    U54HD090258     (LEEDER, JAMES STEVEN)Sep 23, 2016 - Jun 30, 2021
    Genomic- and Ontogeny-Linked Dose Individualization and cLinical Optimization for Kids
    Role: Co-Investigator

    K12HD093427     (DROMERICK, ALEXANDER W)Aug 1, 2017 - Jul 31, 2022
    Neurorehabilitation and Restorative Neuroscience Network
    Role: Co-Investigator

         (MCLAUGHLIN, MATTHEW)Sep 1, 2021 - Aug 31, 2022
    BioNexus Kansas City Patton Award
    Genomic Answers for Kids - Cerebral Palsy
    Role: Principal Investigator

         (MCLAUGHLIN, MATTHEW)Mar 1, 2022 - Feb 28, 2023
    American Society of Clinical Pharmacology and Therapeutics
    Variability in Gabapentin Exposure in Children with Cerebral Palsy
    Role: Principal Investigator

    Collapse Bibliography 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Vova JA, Green MM, Brandenburg JE, Davidson L, Paulson A, Deshpande S, Oleszek JL, Inanoglu D, McLaughlin MJ. A Consensus Statement on the use of Botulinum Toxin in Pediatric Patients. PM R. 2021 Sep 23. PMID: 34558213.
      View in: PubMed
    2. McLaughlin MJ, Caliendo E, Lowder R, Watson WD, Kurowski B, Baum KT, Blackwell LS, Koterba CH, Hoskinson KR, Tlustos SJ, Zimmerman KO, Shah SA, Suskauer SJ. Prescribing Patterns of Amantadine During Pediatric Inpatient Rehabilitation After Traumatic Brain Injury: A Multicentered Retrospective Review From the Pediatric Brain Injury Consortium. J Head Trauma Rehabil. 2021 Jul 26. PMID: 34320554.
      View in: PubMed
    3. Watson WD, Suskauer SJ, Askin G, Nowak S, Baum KT, Gerber LM, Blackwell LS, Koterba CH, Hoskinson KR, Kurowski BG, Mclaughlin MJ, Tlustos SJ, Zimmerman KO, Shah SA. Cognitive Recovery During Inpatient Rehabilitation Following Pediatric Traumatic Brain Injury: A Pediatric Brain Injury Consortium Study. J Head Trauma Rehabil. 2021 Jul-Aug 01; 36(4):253-263. PMID: 33656473.
      View in: PubMed
    4. Caliendo ET, Kim N, Edasery D, Askin G, Nowak S, Gerber LM, Baum KT, Blackwell LS, Koterba CH, Hoskinson KR, Kurowski BG, McLaughlin M, Tlustos SJ, Watson WD, Niogi SN, Suskauer SJ, Shah SA. Acute Imaging Findings Predict Recovery of Cognitive and Motor Function after Inpatient Rehabilitation for Pediatric Traumatic Brain Injury: A Pediatric Brain Injury Consortium Study. J Neurotrauma. 2021 Jul 15; 38(14):1961-1968. PMID: 33504256.
      View in: PubMed
    5. McLaughlin M, Inanoglu D. Decreased clinical response to therapy in pediatric patients with cerebral palsy: Current trends and challenges. J Pediatr Rehabil Med. 2021; 14(2):307-314. PMID: 34092663.
      View in: PubMed
    6. McLaughlin MJ, Ratnasingam D, McGhee E. Variability of Steady State Oral Baclofen Prescribing Practices in Pediatric Patients With Cerebral Palsy. Am J Phys Med Rehabil. 2020 05; 99(5):441-443. PMID: 31688017.
      View in: PubMed
    7. He Q, Chhonker YS, McLaughlin MJ, Murry DJ. Simultaneous Quantitation of S(+)- and R(-)-Baclofen and Its Metabolite in Human Plasma and Cerebrospinal Fluid using LC-APCI-MS/MS: An Application for Clinical Studies. Molecules. 2020 Jan 08; 25(2). PMID: 31936209.
      View in: PubMed
    8. McLaughlin M. Safe and effective medication utilization in pediatric patients requiring rehabilitation services during the Coronavirus pandemic of 2019. J Pediatr Rehabil Med. 2020; 13(3):221-223. PMID: 33185613.
      View in: PubMed
    9. McLaughlin MJ, Fisher MT, Vadivelu S, Ramsey J, Ratnasingam D, McGhee E, Hartman K. A risk-stratified approach toward safely resuming OnabotulinumtoxinA injections based on dosing and ambulatory status in pediatric patients with cerebral palsy during the Coronavirus pandemic of 2019 (COVID-19). J Pediatr Rehabil Med. 2020; 13(3):273-279. PMID: 33252098.
      View in: PubMed
    10. McClellan C, McLaughlin M. Quality in Electrodiagnostic Studies: A Guide for Referring Physicians. Mo Med. 2019 Sep-Oct; 116(5):366-368. PMID: 31645784.
      View in: PubMed
    11. McLaughlin MJ, Wagner J, Shakhnovich V, Carleton B, Leeder JS. Considerations for Implementing Precision Therapeutics for Children. Clin Transl Sci. 2019 03; 12(2):140-150. PMID: 30516322.
      View in: PubMed
    12. McLaughlin MJ, Abdel-Rahman S, Leeder JS. Examining the role of precision medicine with oral baclofen in pediatric patients with cerebral palsy. Curr Phys Med Rehabil Rep. 2019 Mar; 7(1):40-45. PMID: 31579558.
      View in: PubMed
    13. Weinstein SM, McLaughlin M. Ask the Authors. PM R. 2018 03; 10(3):243-244. PMID: 29127054.
      View in: PubMed
    14. McLaughlin MJ, He Y, Brunstrom-Hernandez J, Thio LL, Carleton BC, Ross CJD, Gaedigk A, Lewandowski A, Dai H, Jusko WJ, Leeder JS. Pharmacogenomic Variability of Oral Baclofen Clearance and Clinical Response in Children With Cerebral Palsy. PM R. 2018 03; 10(3):235-243. PMID: 28867665.
      View in: PubMed
    15. Sandritter TL, McLaughlin M, Artman M, Lowry J. The Interplay between Pharmacokinetics and Pharmacodynamics. Pediatr Rev. 2017 May; 38(5):195-206. PMID: 28461611.
      View in: PubMed
    16. McLaughlin M, Marik PE. Dexmedetomidine and delirium in the ICU. Ann Transl Med. 2016 Jun; 4(11):224. PMID: 27385042.
      View in: PubMed
    17. McLaughlin M, Green M. Intradural spinal arteriovenous malformation in a 13-month-old female: A case report. J Pediatr Rehabil Med. 2015; 8(3):247-50. PMID: 26410067.
      View in: PubMed
    18. McLaughlin MJ, Sainani KL. Bonferroni, Holm, and Hochberg corrections: fun names, serious changes to p values. PM R. 2014 Jun; 6(6):544-6. PMID: 24769263.
      View in: PubMed
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