Chlorpromazine
"Chlorpromazine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The prototypical phenothiazine antipsychotic drug. Like the other drugs in this class chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking DOPAMINE RECEPTORS. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup.
| Descriptor ID |
D002746
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| MeSH Number(s) |
D02.886.369.198 D03.494.741.198
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Chlorpromazine".
Below are MeSH descriptors whose meaning is more specific than "Chlorpromazine".
This graph shows the total number of publications written about "Chlorpromazine" by people in this website by year, and whether "Chlorpromazine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chlorpromazine" by people in Profiles.
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Park T, Bae S, Choi S, Kang B, Kim K. Inhibition of nicotinic acetylcholine receptors and calcium channels by clozapine in bovine adrenal chromaffin cells. Biochem Pharmacol. 2001 Apr 15; 61(8):1011-9.
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Lee IS, Park TJ, Suh BC, Kim YS, Rhee IJ, Kim KT. Chlorpromazine-induced inhibition of catecholamine secretion by a differential blockade of nicotinic receptors and L-type Ca2+ channels in rat pheochromocytoma cells. Biochem Pharmacol. 1999 Sep 15; 58(6):1017-24.
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Lantos J, Marjai E. In vitro transfer of multiple resistance observed in vivo during a Salmonella london epidemic. Acta Microbiol Acad Sci Hung. 1980; 27(1):47-53.