 Amiloride
"Amiloride" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pyrazine compound inhibiting SODIUM reabsorption through SODIUM CHANNELS in renal EPITHELIAL CELLS. This inhibition creates a negative potential in the luminal membranes of principal cells, located in the distal convoluted tubule and collecting duct. Negative potential reduces secretion of potassium and hydrogen ions. Amiloride is used in conjunction with DIURETICS to spare POTASSIUM loss. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p705)
| Descriptor ID |
D000584
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| MeSH Number(s) |
D03.383.679.149
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| Concept/Terms |
Amiduret Trom- Amiduret Trom
- Trom, Amiduret
- Trommsdorff Brand of Amiloride Hydrochloride
Amiloberag- Amiloberag
- Berolina Brand of Amiloride Hydrochloride
Midoride- Midoride
- Amrad Brand of Amiloride Hydrochloride
Kaluril- Kaluril
- Alphapharm Brand of Amiloride Hydrochloride
Midamor- Midamor
- Modamide
- Merck Sharp & Dohme Brand of Amiloride Hydrochloride
- Cahill May Roberts Brand of Amiloride Hydrochloride
- Merck Brand of Amiloride Hydrochloride
Amidal- Amidal
- Douglas Brand of Amiloride Hydrochloride
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Below are MeSH descriptors whose meaning is more general than "Amiloride".
Below are MeSH descriptors whose meaning is more specific than "Amiloride".
This graph shows the total number of publications written about "Amiloride" by people in this website by year, and whether "Amiloride" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amiloride" by people in Profiles.
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Arun T, Tomassini V, Sbardella E, de Ruiter MB, Matthews L, Leite MI, Gelineau-Morel R, Cavey A, Vergo S, Craner M, Fugger L, Rovira A, Jenkinson M, Palace J. Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride. Brain. 2013 Jan; 136(Pt 1):106-15.
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