Securin

"Securin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Securin is involved in the control of the metaphase-anaphase transition during MITOSIS. It promotes the onset of anaphase by blocking SEPARASE function and preventing proteolysis of cohesin and separation of sister CHROMATIDS. Overexpression of securin is associated with NEOPLASTIC CELL TRANSFORMATION and tumor formation.

Descriptor ID	D064249
MeSH Number(s)	D12.776.167.504
Concept/Terms	Securin Securin Pituitary Tumor-Transforming Proteins Pituitary Tumor Transforming Proteins PTTG Protein Pituitary Tumor-Transforming Gene Protein

Below are MeSH descriptors whose meaning is more general than "Securin".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Cell Cycle Proteins [D12.776.167]
Securin [D12.776.167.504]

Below are MeSH descriptors whose meaning is related to "Securin".

Below are MeSH descriptors whose meaning is more specific than "Securin".

publications

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