Geminin
"Geminin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Geminin inhibits DNA replication by preventing the incorporation of MCM complex into pre-replication complex. It is absent during G1 phase of the CELL CYCLE and accumulates through S, G2,and M phases. It is degraded at the metaphase-anaphase transition by the ANAPHASE-PROMOTING COMPLEX-CYCLOSOME.
Descriptor ID |
D064248
|
MeSH Number(s) |
D12.776.167.265
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Geminin".
Below are MeSH descriptors whose meaning is more specific than "Geminin".
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