 Toll-Like Receptor 4
"Toll-Like Receptor 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A pattern recognition receptor that interacts with LYMPHOCYTE ANTIGEN 96 and LIPOPOLYSACCHARIDES. It mediates cellular responses to GRAM-NEGATIVE BACTERIA.
| Descriptor ID |
D051197
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| MeSH Number(s) |
D12.776.543.750.705.910.500.400
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| Concept/Terms |
Toll-Like Receptor 4- Toll-Like Receptor 4
- Toll Like Receptor 4
- Toll-4 Receptor
- Toll 4 Receptor
- TLR4 Receptor
- Receptor, TLR4
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Below are MeSH descriptors whose meaning is more general than "Toll-Like Receptor 4".
Below are MeSH descriptors whose meaning is more specific than "Toll-Like Receptor 4".
This graph shows the total number of publications written about "Toll-Like Receptor 4" by people in this website by year, and whether "Toll-Like Receptor 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 0 | 1 | | 2019 | 1 | 1 | 2 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Toll-Like Receptor 4" by people in Profiles.
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Menden HL, Mabry SM, Venkatraman A, Xia S, DeFranco DB, Yu W, Sampath V. The SARS-CoV-2 E protein induces Toll-like receptor 2-mediated neonatal lung injury in a model of COVID-19 viremia that is rescued by the glucocorticoid ciclesonide. Am J Physiol Lung Cell Mol Physiol. 2023 05 01; 324(5):L722-L736.
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Paul AA, Hoffman KL, Hagan JL, Sampath V, Petrosino JF, Pammi M. Fungal cutaneous microbiome and host determinants in preterm and term neonates. Pediatr Res. 2020 08; 88(2):225-233.
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Menden H, Xia S, Mabry SM, Noel-MacDonnell J, Rajasingh J, Ye SQ, Sampath V. Histone deacetylase 6 regulates endothelial MyD88-dependent canonical TLR signaling, lung inflammation, and alveolar remodeling in the developing lung. Am J Physiol Lung Cell Mol Physiol. 2019 09 01; 317(3):L332-L346.
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Li R, Fang L, Pu Q, Bu H, Zhu P, Chen Z, Yu M, Li X, Weiland T, Bansal A, Ye SQ, Wei Y, Jiang J, Wu M. MEG3-4 is a miRNA decoy that regulates IL-1? abundance to initiate and then limit inflammation to prevent sepsis during lung infection. Sci Signal. 2018 06 26; 11(536).
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Rosen JM, Yaggie RE, Woida PJ, Miller RJ, Schaeffer AJ, Klumpp DJ. TRPV1 and the MCP-1/CCR2 Axis Modulate Post-UTI Chronic Pain. Sci Rep. 2018 05 08; 8(1):7188.
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Xia S, Menden HL, Korfhagen TR, Kume T, Sampath V. Endothelial immune activation programmes cell-fate decisions and angiogenesis by inducing angiogenesis regulator DLL4 through TLR4-ERK-FOXC2 signalling. J Physiol. 2018 04 15; 596(8):1397-1417.
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Fawley J, Cuna A, Menden HL, McElroy S, Umar S, Welak SR, Gourlay DM, Li X, Sampath V. Single-Immunoglobulin Interleukin-1-Related Receptor regulates vulnerability to TLR4-mediated necrotizing enterocolitis in a mouse model. Pediatr Res. 2018 01; 83(1-1):164-174.
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Kumar N, Nandula P, Menden H, Jarzembowski J, Sampath V. Placental TLR/NLR expression signatures are altered with gestational age and inflammation. J Matern Fetal Neonatal Med. 2017 Jul; 30(13):1588-1595.
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Rosen JM, Klumpp DJ. Mechanisms of pain from urinary tract infection. Int J Urol. 2014 Apr; 21 Suppl 1:26-32.
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Petrikin JE, Gaedigk R, Leeder JS, Truog WE. Selective Toll--like receptor expression in human fetal lung. Pediatr Res. 2010 Oct; 68(4):335-8.
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