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Last Name
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Janelle R. Noel-MacDonnell, PhD

TitleResearch Faculty PhD
InstitutionChildren's Mercy Kansas City
DepartmentPediatrics
Address2401 Gillham Rd
Kansas City MO 64108
ORCID ORCID Icon0000-0002-8171-6056 Additional info
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    Other Positions
    TitleResearch Assistant Professor of Pediatrics
    InstitutionUniversity of Missouri-Kansas City
    DepartmentPediatrics


    Collapse Biography 
    Collapse education and training
    University of Colorado Denver, Denver, COBS2011Biology
    University of Kansas Medical Center, Kansas City, KSMS2013Biostatistics
    University of Kansas Medical Center, Kansas City, KSPhD2016Biostatistics
    Children's Mercy Hospital, Kansas City, MOFellowship2018Post-Doctoral Research Fellow

    Collapse Overview 

    Collapse Research 
    Collapse research activities and funding
         (Hoffman, Mark)Nov 1, 2018 - Dec 31, 2020
    Midwest Cancer Alliance
    Modeling Pediatric Cancer Trajectories using Deidentified EHR Data
    Role: Statistician
         (Masonbrink)Nov 1, 2019 - Oct 31, 2021
    Merck
    Intervention to facilitate contraception provision by pediatric hospitalists: A feasibility study
    Role Description: Refine our previously developed general sexual risk reduction intervention (SexHealth) to focus on evidence-based contraception counseling and initiation among hospitalized female adolescents.
    Role: Co-Investigator
         (Miller, Hurley)Nov 1, 2019 - Oct 31, 2021
    Merck
    Evaluating the effectiveness of “SexHealth Mobile” on uptake of contraception in women with substance use disorder
    Role Description: Increase use of highly effective contraception among women with substance use disorder.
    Role: Biostatistician
         (Berrios)Sep 1, 2020 - Sep 1, 2023
    Sanofi Genzyme
    Parental psychosocial experiences and outcomes of newborn screening for lysosomal storage disorders
    Role Description: Guide care and further research on improving outcomes for families who receive positive newborn screening results for LSDs
    HD098086-02S1     (Miller)May 1, 2021 - Apr 1, 2022
    NICHD
    A novel community intervention to reduce disparate impact from COVID-19 on vulnerable adolescents
    Role Description: We will conduct a cluster randomized controlled trial to evaluate our novel approach to increasing adolescent access to sexual reproductive health and mental health care.
    Role: Biostatistician
         (Lewing)Jul 1, 2022 - Jun 1, 2023
    KUCC
    Pediatric Analytics for Fever in the Setting of Neutropenia in Pediatric Leukemia
    Role Description: We will develop a large, geographically diverse virtual data cohort of pediatric patients with acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) with febrile neutropenia (FN), with expansion of our cohort to include all encounters of FN.
    Role: Biostatistician
    R01HL162937     (Sampath)Feb 1, 2023 - Jan 31, 2027
    NIH
    DLL4 in lung ontogeny and in BPD
    Role: Co-Investigator

    Collapse Bibliography 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Sacco Casamassima MG, Noel-MacDonnell JR, Oyetunji TA, St Peter SD. Contemporary use of fibrinolytics in the management of pediatric empyema. Pediatr Surg Int. 2024 Nov 04; 40(1):289. PMID: 39495389.
      View in: PubMed
    2. Arganbright J, Crowley TB, Tracy M, Noel-MacDonnell J, Gaiser K, Yaktine L, Moore A, Hamm J, Morrow B, Song H, Giunta V, McGinn DE, Zackai EH, Emanuel B, Elden L, Narayanan S, Raje N, McDonald-McGinn DM. Hearing Loss in Children with 22q11.2 Deletion Syndrome. Laryngoscope. 2024 Sep 21. PMID: 39305214.
      View in: PubMed
    3. Nallani R, Miller BJ, Noel-MacDonnell JR, Tracy M, Brown JR, O'Brien JE, Jensen DR. Impact of Tracheostomy Status on Sternal Wound Infections in Children Following Median Sternotomy. Otolaryngol Head Neck Surg. 2024 Aug 10. PMID: 39126285.
      View in: PubMed
    4. Forseth B, Noel-MacDonnell JR, Hampl S, Carlson JA, Halpin K, Davis A, Phillips T, Shook RP. Relationship between youth cardiometabolic health and physical activity in medical records. PLoS One. 2024; 19(6):e0303583. PMID: 38843219.
      View in: PubMed
    5. Marlor D, Flint J, Noel-MacDonnell JR, Cruz-Centeno N, Stewart S, Elman M, Juang D. Establishing pediatric age-adjusted shock index cut points in trauma patients younger than 1 year. J Trauma Acute Care Surg. 2024 Sep 01; 97(3):386-392. PMID: 38227631.
      View in: PubMed
    6. Taha A, Akangire G, Noel-Macdonnell J, Gladdis T, Manimtim W. The impact of early tracheostomy on neurodevelopmental outcomes of infants with severe bronchopulmonary dysplasia exposed to postnatal corticosteroids. J Perinatol. 2024 Jul; 44(7):979-987. PMID: 38158399.
      View in: PubMed
    7. Cherestal B, Erickson LA, Noel-MacDonnell JR, Shirali G, Graue Hancock HS, Aly D, Files M, Clauss S, Jayaram N. Association Between Remote Monitoring and Interstage Morbidity and Death in Patients With Single-Ventricle Heart Disease Across Socioeconomic Groups. J Am Heart Assoc. 2023 12 05; 12(23):e031069. PMID: 38014668.
      View in: PubMed
    8. Ingram DG, Tracy M, Noel-MacDonnell J, Ghulmiyyah JM, Arganbright JM. Polysomnographic findings in children with 22q deletion & duplication syndrome: relationship to genetic diagnosis, parent-reported symptoms, and calcium levels. Sleep Breath. 2024 Mar; 28(1):489-494. PMID: 37526804.
      View in: PubMed
    9. Tompe AP, Lee GM, Noel-Macdonnell JR, Chan SS. Retrospective cohort comparison between fluoroscopic and radiograph-only exams for evaluation of gastrostomy and gastrojejunostomy tubes. Pediatr Radiol. 2023 09; 53(10):2021-2029. PMID: 37410121.
      View in: PubMed
    10. Fang WB, Medrano M, Cote P, Portsche M, Rao V, Hong Y, Behbod F, Knapp JR, Bloomer C, Noel-Macdonnell J, Cheng N. Transcriptome analysis reveals differences in cell cycle, growth and migration related genes that distinguish fibroblasts derived from pre-invasive and invasive breast cancer. Front Oncol. 2023; 13:1130911. PMID: 37091166.
      View in: PubMed
    11. Masonbrink AR, Noel-MacDonnell J, Staggs VS, Stancil S, Goggin K, Miller MK. Feasibility of a Contraception Intervention for Hospitalized Adolescents and Young Adults. Hosp Pediatr. 2023 04 01; 13(4):337-344. PMID: 36897226.
      View in: PubMed
    12. Hurley EA, Goggin K, Pi?a-Brugman K, Noel-MacDonnell JR, Allen A, Finocchario-Kessler S, Miller MK. Contraception use among individuals with substance use disorder increases tenfold with patient-centered, mobile services: a quasi-experimental study. Harm Reduct J. 2023 03 06; 20(1):28. PMID: 36879314.
      View in: PubMed
    13. Arganbright JM, Hankey PB, Tracy M, Narayanan S, Noel-MacDonnell J, Ingram D. Tonsillectomy in Children with 22q11.2 Deletion Syndrome. Genes (Basel). 2022 11 23; 13(12). PMID: 36553454.
      View in: PubMed
    14. Akangire G, Lachica C, Noel-MacDonnell J, Begley A, Sampath V, Truog W, Manimtim W. Outcomes of infants with severe bronchopulmonary dysplasia who received tracheostomy and home ventilation. Pediatr Pulmonol. 2023 03; 58(3):753-762. PMID: 36377273.
      View in: PubMed
    15. Arganbright JM, Tracy M, Feldt M, Narayanan S, Mahadev A, Noel-MacDonnell J. Postoperative Hypocalcemia following Non-Cardiac Surgical Procedures in Children with 22q11.2 Deletion Syndrome. Genes (Basel). 2022 10 20; 13(10). PMID: 36292790.
      View in: PubMed
    16. Erickson LA, Ricketts A, Swanson T, Weiner J, Hasnie UA, Bonessa K, Noel-Macdonnell J, Russell CL. Determinants of Length of Stay after Neonatal Cardiac Surgery Using Path Analysis. West J Nurs Res. 2023 04; 45(4):306-315. PMID: 36217759.
      View in: PubMed
    17. Raje NR, Noel-MacDonnell JR, Shortt KA, Gigliotti NM, Chan MA, Heruth DP. T Cell Transcriptome in Chromosome 22q11.2 Deletion Syndrome. J Immunol. 2022 09 01; 209(5):874-885. PMID: 35940635.
      View in: PubMed
    18. Schmidt K, Noel-MacDonnell J, Vyhlidal C, Heruth DP, Singh V, Ahmed AA, Hudson T, Williams V, Shakhnovich V. Characterization of the Mucosally-Adherent Duodenal Microbiome in Children with and without Crohn's Disease. Pharmaceuticals (Basel). 2022 Jul 11; 15(7). PMID: 35890149.
      View in: PubMed
    19. Whittington M, Goggin K, Noel-MacDonnell J, Hathaway D, Remy L, Aholt D, Clark D, Miller C, Ashbaugh C, Wakefield M, Ellis RB, Russell C. Cost-Effectiveness Analysis: Personal Systems Approach in Improving Medication Adherence in Adult Kidney Transplant Patients. J Healthc Qual. 2022 Jul-Aug 01; 44(4):240-252. PMID: 35759613.
      View in: PubMed
    20. Lee B, Yin D, August K, Noel-Macdonell J, Tracy M, Jensen D. Clinical predictors of invasive fungal rhinosinusitis in a tertiary pediatric hospital. Int J Pediatr Otorhinolaryngol. 2022 Apr; 155:111065. PMID: 35183919.
      View in: PubMed
    21. Sharma S, Repnikova E, Noel-MacDonnell JR, LePichon JB. Diagnostic yield of genetic testing in 324 infants with hypotonia. Clin Genet. 2021 12; 100(6):752-757. PMID: 34480364.
      View in: PubMed
    22. Campbell N, Tsai A, Reading B, Thompson M, Noel-MacDonnell J, Schwartz R, Sheeran P. Risk factors for anesthetic-related complications in pediatric patients with a newly diagnosed mediastinal mass. Paediatr Anaesth. 2021 Nov; 31(11):1234-1240. PMID: 34482581.
      View in: PubMed
    23. Beversdorf DQ, Shah A, Jhin A, Noel-MacDonnell J, Hecht P, Ferguson BJ, Bruce D, Tilley M, Talebizadeh Z. microRNAs and Gene-Environment Interactions in Autism: Effects of Prenatal Maternal Stress and the SERT Gene on Maternal microRNA Expression. Front Psychiatry. 2021; 12:668577. PMID: 34290629.
      View in: PubMed
    24. Kaye A, Tracy M, Noel-MacDonnell J, Dent K. Conversion Furlow Palatoplasty and the Use of Preoperative Video Nasendoscopy. Cleft Palate Craniofac J. 2022 05; 59(5):629-636. PMID: 34000849.
      View in: PubMed
    25. Hansen TP, Noel-MacDonnell J, Kuckelman S, Norberg M, Truog W, Manimtim W. A multidisciplinary chronic lung disease team in a neonatal intensive care unit is associated with increased survival to discharge of infants with tracheostomy. J Perinatol. 2021 08; 41(8):1963-1971. PMID: 33795789.
      View in: PubMed
    26. Hurley EA, Pi?a K, Cegielski V, Noel-MacDonnell JR, Miller MK. Recovering from substance use disorders during the early months of the COVID-19 pandemic: A mixed-methods longitudinal study of women in Kansas City. J Subst Abuse Treat. 2021 10; 129:108378. PMID: 34080549.
      View in: PubMed
    27. Yimer MA, Tisma-Dupanovic S, Malloy-Walton L, Connelly D, Noel-Macdonnell J, O' Brien J, Papagiannis J. Post-operative arrhythmias in patients with hypoplastic left heart syndrome and anatomic variants: incidence, type, and course. Cardiol Young. 2021 Sep; 31(9):1412-1418. PMID: 33685535.
      View in: PubMed
    28. Wood NM, Davis S, Lewing K, Noel-MacDonnell J, Glynn EF, Caragea D, Hoffman MA. Aligning EHR Data for Pediatric Leukemia With Standard Protocol Therapy. JCO Clin Cancer Inform. 2021 03; 5:239-251. PMID: 33656914.
      View in: PubMed
    29. Carlson JA, Shook RP, Davis AM, Papa A, Steel C, Bejarano C, Noel-MacDonnell JR, Summar S, Dean K, Hampl SE. Investigating associations between physical activity-related neighborhood built environment features and child weight status to inform local practice. Soc Sci Med. 2021 02; 270:113694. PMID: 33485006.
      View in: PubMed
    30. Rentea RM, Noel-MacDonnell JR, Bucher BT, Dorman MR, Lautz TB, Pruitt LCC, Oyetunji TA. Impact of Botulinum Toxin on Hirschsprung-Associated Enterocolitis After Primary Pull-Through. J Surg Res. 2021 05; 261:95-104. PMID: 33422904.
      View in: PubMed
    31. Muelleman TJ, Kavookjian H, Asmar J, Patel K, Nielsen D, Summers K, Tracy M, Noel-MacDonnell J, Staecker H, Ledbetter L, Weatherly R. Internal Auditory Canal Diverticula in Children: A Congenital Variant. Laryngoscope. 2021 05; 131(5):E1683-E1687. PMID: 33200834.
      View in: PubMed
    32. Russell G, Kasraie N, Noel-MacDonnell J, Robinson AL, Chan SS. Identification of aspirated radiolucent foreign bodies in the pediatric airway using digital tomosynthesis: a multireader phantom study. J Med Imaging (Bellingham). 2020 Sep; 7(5):055502. PMID: 37476354.
      View in: PubMed
    33. Akangire G, Taylor JB, McAnany S, Noel-MacDonnell J, Lachica C, Sampath V, Manimtim W. Respiratory, growth, and survival outcomes of infants with tracheostomy and ventilator dependence. Pediatr Res. 2021 08; 90(2):381-389. PMID: 33010793.
      View in: PubMed
    34. Behrle NI, O'Brien J, Kiaffas M, Noel-MacDonnell J, Shirali G, Parthiban A. Reducing Transthoracic Echocardiographic Diagnostic Error in Congenital Heart Disease. J Am Soc Echocardiogr. 2020 09; 33(9):1156-1158. PMID: 32418656.
      View in: PubMed
    35. Akangire G, Simpson E, Weiner J, Noel-MacDonnell J, Petrikin J, Sheehan M. Implementation of the Neonatal Sepsis Calculator in Early-Onset Sepsis and Maternal Chorioamnionitis. Adv Neonatal Care. 2020 Feb; 20(1):25-32. PMID: 31569094.
      View in: PubMed
    36. Cammack B, Noel-MacDonnell J, Cuna A, Manimtim W. Impact of tracheostomy on language and cognitive development in infants with severe bronchopulmonary dysplasia. J Perinatol. 2020 02; 40(2):299-305. PMID: 31659237.
      View in: PubMed
    37. Berrios C, Koertje C, Noel-MacDonnell J, Soden S, Lantos J. Parents of newborns in the NICU enrolled in genome sequencing research: hopeful, but not na?ve. Genet Med. 2020 02; 22(2):416-422. PMID: 31467447.
      View in: PubMed
    38. Rudder BS, Easley SJ, Robinson AL, Noel-MacDonnell JR, Nielsen DB. Effects of an MRI Try Without program on patient access. Pediatr Radiol. 2019 12; 49(13):1712-1717. PMID: 31392365.
      View in: PubMed
    39. Parham D, Reed D, Olicker A, Parrill F, Sharma J, Brunkhorst J, Noel-MacDonnell J, Voos K. Families as educators: a family-centered approach to teaching communication skills to neonatology fellows. J Perinatol. 2019 10; 39(10):1392-1398. PMID: 31371832.
      View in: PubMed
    40. Menden H, Xia S, Mabry SM, Noel-MacDonnell J, Rajasingh J, Ye SQ, Sampath V. Histone deacetylase 6 regulates endothelial MyD88-dependent canonical TLR signaling, lung inflammation, and alveolar remodeling in the developing lung. Am J Physiol Lung Cell Mol Physiol. 2019 09 01; 317(3):L332-L346. PMID: 31268348.
      View in: PubMed
    41. Kueffner R, Zach N, Bronfeld M, Norel R, Atassi N, Balagurusamy V, Di Camillo B, Chio A, Cudkowicz M, Dillenberger D, Garcia-Garcia J, Hardiman O, Hoff B, Knight J, Leitner ML, Li G, Mangravite L, Norman T, Wang L, Xiao J, Fang WC, Peng J, Yang C, Chang HJ, Stolovitzky G. Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach. Sci Rep. 2019 01 24; 9(1):690. PMID: 30679616.
      View in: PubMed
    42. Li Q, Noel-MacDonnell JR, Koestler DC, Goode EL, Fridley BL. Subject level clustering using a negative binomial model for small transcriptomic studies. BMC Bioinformatics. 2018 Dec 12; 19(1):474. PMID: 30541426.
      View in: PubMed
    43. Shook RP, Halpin K, Carlson JA, Davis A, Dean K, Papa A, Sherman AK, Noel-MacDonnell JR, Summar S, Krueger G, Markenson D, Hampl S. Adherence With Multiple National Healthy Lifestyle Recommendations in a Large Pediatric Center Electronic Health Record and Reduced Risk of Obesity. Mayo Clin Proc. 2018 09; 93(9):1247-1255. PMID: 30060957.
      View in: PubMed
    44. Qayum O, Alshami N, Ibezim CF, Reid KJ, Noel-MacDonnell JR, Raghuveer G. Lipoprotein (a): Examination of Cardiovascular Risk in a Pediatric Referral Population. Pediatr Cardiol. 2018 Dec; 39(8):1540-1546. PMID: 29948030.
      View in: PubMed
    45. Halpin K, Noel-MacDonnell JR, Yan Y. Examining the Impact of Race and Rurality on Health Differences among Overweight Youth Accessing Pediatric Endocrinology Care. 2018; 12(1).
    46. Akangire G, Manimtim W, Nyp MF, Noel-MacDonnell J, Kays AN, Truog WE, Taylor JB. Clinical Outcomes among Diagnostic Subgroups of Infants with Severe Bronchopulmonary Dysplasia through 2 Years of Age. Am J Perinatol. 2018 12; 35(14):1376-1387. PMID: 29852508.
      View in: PubMed
    47. Noel-MacDonnell JR, Usset J, Goode EL, Fridley BL. Assessment of data transformations for model-based clustering of RNA-Seq data. PLoS One. 2018; 13(2):e0191758. PMID: 29485993.
      View in: PubMed
    48. Ahmed M, Machado PM, Miller A, Spicer C, Herbelin L, He J, Noel J, Wang Y, McVey AL, Pasnoor M, Gallagher P, Statland J, Lu CH, Kalmar B, Brady S, Sethi H, Samandouras G, Parton M, Holton JL, Weston A, Collinson L, Taylor JP, Schiavo G, Hanna MG, Barohn RJ, Dimachkie MM, Greensmith L. Targeting protein homeostasis in sporadic inclusion body myositis. Sci Transl Med. 2016 Mar 23; 8(331):331ra41. PMID: 27009270.
      View in: PubMed
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