Methylenetetrahydrofolate Reductase (NADPH2)
"Methylenetetrahydrofolate Reductase (NADPH2)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A flavoprotein amine oxidoreductase that catalyzes the reversible conversion of 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. This enzyme was formerly classified as EC 1.1.1.171.
Descriptor ID |
D042965
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MeSH Number(s) |
D08.811.682.662.290 D12.776.331.775
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Concept/Terms |
Methylenetetrahydrofolate Reductase (NADPH2)- Methylenetetrahydrofolate Reductase (NADPH2)
- Methylenetetrahydrofolate Reductase (NADPH)
- Methylene-THF Reductase (NADPH)
- Methylenetetrahydrofolate Reductase
- 5,10-Methylenetetrahydrofolate Reductase (NADPH)
- Methylene Tetrahydrofolate Reductase
- Tetrahydrofolate Reductase, Methylene
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Below are MeSH descriptors whose meaning is more general than "Methylenetetrahydrofolate Reductase (NADPH2)".
Below are MeSH descriptors whose meaning is more specific than "Methylenetetrahydrofolate Reductase (NADPH2)".
This graph shows the total number of publications written about "Methylenetetrahydrofolate Reductase (NADPH2)" by people in this website by year, and whether "Methylenetetrahydrofolate Reductase (NADPH2)" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 | 2012 | 0 | 1 | 1 | 2015 | 1 | 0 | 1 | 2019 | 1 | 0 | 1 | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Methylenetetrahydrofolate Reductase (NADPH2)" by people in Profiles.
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Bopp EA, Poweleit EA, Cox MO, Farrow JE, Strawn JR, Patino Duran LR, Prows CA, DelBello MP, Ramsey LB. A retrospective examination of adjunctive L-methylfolate in children and adolescents with unipolar depression. J Affect Disord. 2022 09 01; 312:315-321.
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Chan D, Shao X, Dumargne MC, Aarabi M, Simon MM, Kwan T, Bailey JL, Robaire B, Kimmins S, San Gabriel MC, Zini A, Librach C, Moskovtsev S, Grundberg E, Bourque G, Pastinen T, Trasler JM. Customized MethylC-Capture Sequencing to Evaluate Variation in the Human Sperm DNA Methylome Representative of Altered Folate Metabolism. Environ Health Perspect. 2019 08; 127(8):87002.
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Aarabi M, San Gabriel MC, Chan D, Behan NA, Caron M, Pastinen T, Bourque G, MacFarlane AJ, Zini A, Trasler J. High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism. Hum Mol Genet. 2015 Nov 15; 24(22):6301-13.
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Becker ML, van Haandel L, Gaedigk R, Thomas B, Hoeltzel MF, Lasky A, Dai H, Stobaugh J, Leeder JS. Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability. Pharmacogenet Genomics. 2012 Apr; 22(4):236-46.
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Alfthan G, Laurinen MS, Valsta LM, Pastinen T, Aro A. Folate intake, plasma folate and homocysteine status in a random Finnish population. Eur J Clin Nutr. 2003 Jan; 57(1):81-8.
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