 CCAAT-Enhancer-Binding Proteins
"CCAAT-Enhancer-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT. The typical CCAAT-enhancer binding protein forms dimers and consists of an activation domain, a DNA-binding basic region, and a leucine-rich dimerization domain (LEUCINE ZIPPERS). CCAAT-BINDING FACTOR is structurally distinct type of CCAAT-enhancer binding protein consisting of a trimer of three different subunits.
| Descriptor ID |
D022762
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| MeSH Number(s) |
D12.776.260.108.124 D12.776.660.167 D12.776.930.127.124
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| Concept/Terms |
CCAAT-Enhancer-Binding Proteins- CCAAT-Enhancer-Binding Proteins
- CCAAT Enhancer Binding Proteins
- CAAT-Enhancer Binding Protein
- Binding Protein, CAAT-Enhancer
- CAAT Enhancer Binding Protein
- CCAAT-Enhancer-Binding Protein
- CCAAT Enhancer Binding Protein
- C-EBP Protein
- C EBP Protein
- C-EBP Nuclear Protein
- C EBP Nuclear Protein
- Nuclear Protein, C-EBP
- CAAT-Enhancer-Binding Proteins
- CAAT Enhancer Binding Proteins
- C-EBP Proteins
- C EBP Proteins
- CCAAT Sequence-Specific DNA-Binding Proteins
- CCAAT Sequence Specific DNA Binding Proteins
- Nuclear Protein C-EBP
- C-EBP, Nuclear Protein
- Nuclear Protein C EBP
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Below are MeSH descriptors whose meaning is more general than "CCAAT-Enhancer-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "CCAAT-Enhancer-Binding Proteins".
This graph shows the total number of publications written about "CCAAT-Enhancer-Binding Proteins" by people in this website by year, and whether "CCAAT-Enhancer-Binding Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "CCAAT-Enhancer-Binding Proteins" by people in Profiles.
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Tarlock K, Lamble AJ, Wang YC, Gerbing RB, Ries RE, Loken MR, Brodersen LE, Pardo L, Leonti A, Smith JL, Hylkema TA, Woods WG, Cooper TM, Kolb EA, Gamis AS, Aplenc R, Alonzo TA, Meshinchi S. CEBPA-bZip mutations are associated with favorable prognosis in de novo AML: a report from the Children's Oncology Group. Blood. 2021 09 30; 138(13):1137-1147.
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Maxson JE, Ries RE, Wang YC, Gerbing RB, Kolb EA, Thompson SL, Guidry Auvil JM, Marra MA, Ma Y, Zong Z, Mungall AJ, Moore R, Long W, Gesuwan P, Davidsen TM, Hermida LC, Hughes SB, Farrar JE, Radich JP, Smith MA, Gerhard DS, Gamis AS, Alonzo TA, Meshinchi S. CSF3R mutations have a high degree of overlap with CEBPA mutations in pediatric AML. Blood. 2016 06 16; 127(24):3094-8.
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Hsu W, Kerppola TK, Chen PL, Curran T, Chen-Kiang S. Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region. Mol Cell Biol. 1994 Jan; 14(1):268-76.
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