 Cytochrome P-450 CYP2E1
"Cytochrome P-450 CYP2E1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An ethanol-inducible cytochrome P450 enzyme that metabolizes several precarcinogens, drugs, and solvents to reactive metabolites. Substrates include ETHANOL; INHALATION ANESTHETICS; BENZENE; ACETAMINOPHEN and other low molecular weight compounds. CYP2E1 has been used as an enzyme marker in the study of alcohol abuse.
| Descriptor ID |
D019392
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| MeSH Number(s) |
D08.244.453.300 D08.811.682.662.582.338 D08.811.682.690.708.170.200 D12.776.422.220.453.300
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| Concept/Terms |
Cytochrome P-450 CYP2E1- Cytochrome P-450 CYP2E1
- Cytochrome P 450 CYP2E1
- CYP 2E1
- CYP IIE1
- CYP2E1
- N-Nitrosodimethylamine Demethylase
- N Nitrosodimethylamine Demethylase
- Cytochrome P-450 (ALC)
- Cytochrome P-450 IIE1
- Cytochrome P 450 IIE1
- Cytochrome P-450-J
- Cytochrome P 450 J
- Cytochrome P450 2E1
- Dimethylnitrosamine N-Demethylase
- Dimethylnitrosamine N Demethylase
- 4-Nitrophenol-2-Hydroxylase
- 4 Nitrophenol 2 Hydroxylase
- CYPIIE1
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Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 CYP2E1".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 CYP2E1".
This graph shows the total number of publications written about "Cytochrome P-450 CYP2E1" by people in this website by year, and whether "Cytochrome P-450 CYP2E1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytochrome P-450 CYP2E1" by people in Profiles.
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McCarthy ET, Zhou J, Eckert R, Genochio D, Sharma R, Oni O, De A, Srivastava T, Sharma R, Savin VJ, Sharma M. Ethanol at low concentrations protects glomerular podocytes through alcohol dehydrogenase and 20-HETE. Prostaglandins Other Lipid Mediat. 2015 Jan-Mar; 116-117:88-98.
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Leeder JS, Gaedigk A, Lu X, Cook VA. Epitope mapping studies with human anti-cytochrome P450 3A antibodies. Mol Pharmacol. 1996 Feb; 49(2):234-43.
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Riley RJ, Smith G, Wolf CR, Cook VA, Leeder JS. Human anti-endoplasmic reticulum autoantibodies produced in aromatic anticonvulsant hypersensitivity reactions recognise rodent CYP3A proteins and a similarly regulated human P450 enzyme(s) Biochem Biophys Res Commun. 1993 Feb 26; 191(1):32-40.
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