 Pravastatin
"Pravastatin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antilipemic fungal metabolite isolated from cultures of Nocardia autotrophica. It acts as a competitive inhibitor of HMG CoA reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES).
| Descriptor ID |
D017035
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| MeSH Number(s) |
D02.455.426.559.847.638.930 D04.615.638.930
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| Concept/Terms |
Vasten- Vasten
- Aventis Brand of Pravastatin Sodium
Lin-Pravastatin- Lin-Pravastatin
- Lin Pravastatin
- Linson Pharma Brand of Pravastatin Sodium
Lipemol- Lipemol
- Squibb Brand of Pravastatin Sodium
Liplat- Liplat
- Esteve Brand of Pravastatin Sodium
Nu-Pravastatin- Nu-Pravastatin
- Nu Pravastatin
- Nu-Pharma Brand of Pravastatin Sodium
Prareduct- Prareduct
- Sankyo Brand of Pravastatin Sodium
- Mevalotin
Pravachol- Pravachol
- Elisor
- Selektine
- Pravacol
- Pravasin
- Bristol-Myers Squibb Brand of Pravastatin Sodium
- Lipostat
SQ-31000- SQ-31000
- SQ 31000
- SQ31000
- SQ-31,000
- SQ 31,000
- SQ31,000
Apo-Pravastatin- Apo-Pravastatin
- Apo Pravastatin
- Apotex Brand of Pravastatin Sodium
Bristacol- Bristacol
- Juste Brand of Pravastatin Sodium
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Below are MeSH descriptors whose meaning is more general than "Pravastatin".
Below are MeSH descriptors whose meaning is more specific than "Pravastatin".
This graph shows the total number of publications written about "Pravastatin" by people in this website by year, and whether "Pravastatin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pravastatin" by people in Profiles.
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Wagner JB, Ruggiero M, Leeder JS, Hagenbuch B. Functional Consequences of Pravastatin Isomerization on OATP1B1-Mediated Transport. Drug Metab Dispos. 2020 11; 48(11):1192-1198.
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Toth EL, Clarke JD, Csanaky IL, Cherrington NJ. Interaction of Oatp1b2 expression and nonalcoholic steatohepatitis on pravastatin plasma clearance. Biochem Pharmacol. 2020 04; 174:113780.
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Wagner JB, Abdel-Rahman S, Gaedigk R, Gaedigk A, Raghuveer G, Staggs VS, Kauffman R, Van Haandel L, Leeder JS. Impact of Genetic Variation on Pravastatin Systemic Exposure in Pediatric Hypercholesterolemia. Clin Pharmacol Ther. 2019 06; 105(6):1501-1512.
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van Haandel L, Gibson KT, Leeder JS, Wagner JB. Quantification of pravastatin acid, lactone and isomers in human plasma by UHPLC-MS/MS and its application to a pediatric pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Feb 15; 1012-1013:169-77.
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