Mice homozygous for the mutant autosomal recessive gene "scid" which is located on the centromeric end of chromosome 16. These mice lack mature, functional lymphocytes and are thus highly susceptible to lethal opportunistic infections if not chronically treated with antibiotics. The lack of B- and T-cell immunity resembles severe combined immunodeficiency (SCID) syndrome in human infants. SCID mice are useful as animal models since they are receptive to implantation of a human immune system producing SCID-human (SCID-hu) hematochimeric mice.

Descriptor ID	D016513
MeSH Number(s)	B01.050.150.900.649.865.635.505.500.550.780
Concept/Terms	Mice, SCID Mice, SCID Severe Combined Immunodeficient Mice SCID Mice Immunodeficient Mice, Severe Combined Mouse, SCID SCID Mouse Mouse, SCID-hu Mouse, SCID-hu Mouse, SCID hu SCID-hu Mouse SCID-hu Mice Mice, SCID-hu SCID hu Mice

Below are MeSH descriptors whose meaning is more general than "Mice, SCID".

Below are MeSH descriptors whose meaning is related to "Mice, SCID".

Below are MeSH descriptors whose meaning is more specific than "Mice, SCID".