 Histocompatibility Antigens Class I
"Histocompatibility Antigens Class I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Membrane glycoproteins consisting of an alpha subunit and a BETA 2-MICROGLOBULIN beta subunit. In humans, highly polymorphic genes on CHROMOSOME 6 encode the alpha subunits of class I antigens and play an important role in determining the serological specificity of the surface antigen. Class I antigens are found on most nucleated cells and are generally detected by their reactivity with alloantisera. These antigens are recognized during GRAFT REJECTION and restrict cell-mediated lysis of virus-infected cells.
| Descriptor ID |
D015395
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| MeSH Number(s) |
D12.776.395.550.489 D12.776.543.550.421 D23.050.301.500.100 D23.050.705.552.100
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| Concept/Terms |
Histocompatibility Antigens Class I- Histocompatibility Antigens Class I
- Class I Histocompatibility Antigens
- Class I Major Histocompatibility Antigens
- Class I Antigens
- Antigens, Class I
- I Antigens, Class
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Below are MeSH descriptors whose meaning is more general than "Histocompatibility Antigens Class I".
Below are MeSH descriptors whose meaning is more specific than "Histocompatibility Antigens Class I".
This graph shows the total number of publications written about "Histocompatibility Antigens Class I" by people in this website by year, and whether "Histocompatibility Antigens Class I" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 1 | 0 | 1 | | 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2000 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 1 | 0 | 1 | | 2006 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Histocompatibility Antigens Class I" by people in Profiles.
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Chaudhuri A, Ozawa M, Everly MJ, Ettenger R, Dharnidharka V, Benfield M, Mathias R, Portale A, McDonald R, Harmon W, Kershaw D, Vehaskari VM, Kamil E, Baluarte HJ, Warady B, Li L, Sigdel TK, Hsieh SC, Dai H, Naesens M, Waskerwitz J, Salvatierra O, Terasaki PI, Sarwal MM. The clinical impact of humoral immunity in pediatric renal transplantation. J Am Soc Nephrol. 2013 Mar; 24(4):655-64.
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Fischer RT, Turnquist HR, Wang Z, Beer-Stolz D, Thomson AW. Rapamycin-conditioned, alloantigen-pulsed myeloid dendritic cells present donor MHC class I/peptide via the semi-direct pathway and inhibit survival of antigen-specific CD8(+) T cells in vitro and in vivo. Transpl Immunol. 2011 Jul; 25(1):20-6.
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Bryan CF, McDonald SB, Luger AM, Shield CF, Winklhofer FT, Michael Borkon A, Warady BA, Aeder MI, Murillo D. Successful renal transplantation despite low levels of donor-specific HLA class I antibody without IVIg or plasmapheresis. Clin Transplant. 2006 Sep-Oct; 20(5):563-70.
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Bray RA, Nolen JD, Larsen C, Pearson T, Newell KA, Kokko K, Guasch A, Tso P, Mendel JB, Gebel HM. Transplanting the highly sensitized patient: The emory algorithm. Am J Transplant. 2006 Oct; 6(10):2307-15.
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Bryan CF, McDonald SB, Baier KA, Luger AM, Aeder MI, Murillo D, Muruve NA, Nelson PW, Shield CF, Warady BA. Flow cytometry beads rather than the antihuman globulin method should be used to detect HLA Class I IgG antibody (PRA) in cadaveric renal regraft candidates. Clin Transplant. 2002; 16 Suppl 7:15-23.
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Bryan CF, Luger AM, Martinez J, Muruve N, Nelson PW, Pierce GE, Ross G, Shield CF, Warady BA, Aeder MI, Helling TS. Cold ischemia time: an independent predictor of increased HLA class I antibody production after rejection of a primary cadaveric renal allograft. Transplantation. 2001 Apr 15; 71(7):875-9.
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Bryan CF, Shield CF, Pierce GE, Warady BA, Aeder MI, Martinez J, Luger AM, Nelson PW, Ross G, Muruve N, Mitchell SI. Successful cadaveric renal transplantation of patients highly sensitized to HLA Class I antigens. Clin Transplant. 2000 Feb; 14(1):79-84.
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Bryan CF, Baier KA, Nelson PW, Luger AM, Martinez J, Pierce GE, Ross G, Shield CF, Warady BA, Aeder MI, Helling TS, Muruve N. Long-term graft survival is improved in cadaveric renal retransplantation by flow cytometric crossmatching. Transplantation. 1998 Dec 27; 66(12):1827-32.
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Hoffman M, Tremaine M, Mansfield J, Betley M. Biochemical and mutational analysis of the histidine residues of staphylococcal enterotoxin A. Infect Immun. 1996 Mar; 64(3):885-90.
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Bryan CF, Baier KA, Flora-Ginter G, Shield CF, Warady BA, Aeder MI, Borkon AM, Estep TH, Forster J, Landreneau MD, et al. Detection of HLA IgG antibodies by two enzyme-linked immunoassays, solubilized HLA class I and PRA-STAT. Comparison with the AHG PRA. Transplantation. 1995 Dec 27; 60(12):1588-94.
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