HLA-B Antigens
"HLA-B Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Class I human histocompatibility (HLA) surface antigens encoded by more than 30 detectable alleles on locus B of the HLA complex, the most polymorphic of all the HLA specificities. Several of these antigens (e.g., HLA-B27, -B7, -B8) are strongly associated with predisposition to rheumatoid and other autoimmune disorders. Like other class I HLA determinants, they are involved in the cellular immune reactivity of cytolytic T lymphocytes.
Descriptor ID |
D015235
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MeSH Number(s) |
D12.776.395.550.489.500 D12.776.543.550.421.500 D23.050.301.500.100.500 D23.050.301.500.450.380 D23.050.705.552.100.500 D23.050.705.552.450.380
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Concept/Terms |
HLA-B Antigens- HLA-B Antigens
- HLA B Antigens
- Antigens, HLA-B
- Antigens, HLA B
- HLA-B
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Below are MeSH descriptors whose meaning is more general than "HLA-B Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-B Antigens".
This graph shows the total number of publications written about "HLA-B Antigens" by people in this website by year, and whether "HLA-B Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 1 | 0 | 1 | 2018 | 0 | 1 | 1 | 2020 | 1 | 0 | 1 | 2021 | 0 | 1 | 1 | 2022 | 0 | 1 | 1 | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "HLA-B Antigens" by people in Profiles.
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Stancil SL, Sandritter T, Strawn JR. Pharmacogenetics and Oxcarbazepine in Children and Adolescents: Beyond HLA-B*15:02. J Child Adolesc Psychopharmacol. 2024 02; 34(1):61-66.
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Goldman JL, Miller JO, Miller N, Eveleigh R, Gibson A, Phillips EJ, Pastinen T. HLA-B*07:02 and HLA-C*07:02 are associated with trimethoprim-sulfamethoxazole respiratory failure. Pharmacogenomics J. 2022 03; 22(2):124-129.
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Nyanhete TE, Edwards RJ, LaBranche CC, Mansouri K, Eaton A, Dennison SM, Saunders KO, Goodman D, Janowska K, Spreng RL, Zhang L, Mudrak SV, Hope TJ, Hora B, Bradley T, Georgiev IS, Montefiori DC, Acharya P, Tomaras GD. Polyclonal Broadly Neutralizing Antibody Activity Characterized by CD4 Binding Site and V3-Glycan Antibodies in a Subset of HIV-1 Virus Controllers. Front Immunol. 2021; 12:670561.
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Karnes JH, Rettie AE, Somogyi AA, Huddart R, Fohner AE, Formea CM, Ta Michael Lee M, Llerena A, Whirl-Carrillo M, Klein TE, Phillips EJ, Mintzer S, Gaedigk A, Caudle KE, Callaghan JT. Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2C9 and HLA-B Genotypes and Phenytoin Dosing: 2020 Update. Clin Pharmacol Ther. 2021 02; 109(2):302-309.
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Koskela S, Ritari J, Hyv?rinen K, Kwan T, Niittyvuopio R, It?l?-Remes M, Pastinen T, Partanen J. Hidden genomic MHC disparity between HLA-matched sibling pairs in hematopoietic stem cell transplantation. Sci Rep. 2018 03 29; 8(1):5396.
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Luger AM, Bryan CF, O'Brien BJ, Pierce GE, Shield CF, Warady BA, Aeder MI, Landreneau MD, Nelson PW, Ross G. Do African-Americans wait longer for a kidney because of HLA class I antibody specificities and panel-reactive antibody sensitization? Transplant Proc. 1996 Feb; 28(1):157-9.
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