 Histocompatibility Antigens Class II
"Histocompatibility Antigens Class II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Large, transmembrane, non-covalently linked glycoproteins (alpha and beta). Both chains can be polymorphic although there is more structural variation in the beta chains. The class II antigens in humans are called HLA-D ANTIGENS and are coded by a gene on chromosome 6. In mice, two genes named IA and IE on chromosome 17 code for the H-2 antigens. The antigens are found on B-lymphocytes, macrophages, epidermal cells, and sperm and are thought to mediate the competence of and cellular cooperation in the immune response. The term IA antigens used to refer only to the proteins encoded by the IA genes in the mouse, but is now used as a generic term for any class II histocompatibility antigen.
| Descriptor ID |
D000949
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| MeSH Number(s) |
D12.776.395.550.509 D12.776.543.550.423 D23.050.301.500.400 D23.050.705.552.410
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| Concept/Terms |
Histocompatibility Antigens Class II- Histocompatibility Antigens Class II
- I-A-Antigen
- I A Antigen
- IA Antigen
- Antigen, IA
- Ia Antigens
- Antigens, Ia
- Ia-Like Antigens
- Antigens, Ia-Like
- Ia Like Antigens
- Class II Major Histocompatibility Antigens
- Immune-Response-Associated Antigens
- Antigens, Immune-Response-Associated
- Immune Response Associated Antigens
- Antigens, Immune Response
- Class II Antigen
- Antigen, Class II
- Class II Antigens
- Antigens, Class II
- Class II Histocompatibility Antigens
- I-A Antigen
- Antigen, I-A
- Immune Response Antigens
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Below are MeSH descriptors whose meaning is more general than "Histocompatibility Antigens Class II".
Below are MeSH descriptors whose meaning is more specific than "Histocompatibility Antigens Class II".
This graph shows the total number of publications written about "Histocompatibility Antigens Class II" by people in this website by year, and whether "Histocompatibility Antigens Class II" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 1 | 0 | 1 | | 2003 | 1 | 0 | 1 | | 2006 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Histocompatibility Antigens Class II" by people in Profiles.
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Nyanhete TE, Frisbee AL, Bradley T, Faison WJ, Robins E, Payne T, Freel SA, Sawant S, Weinhold KJ, Wiehe K, Haynes BF, Ferrari G, Li QJ, Moody MA, Tomaras GD. HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers. Sci Rep. 2019 07 15; 9(1):10165.
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Turnquist HR, Raimondi G, Zahorchak AF, Fischer RT, Wang Z, Thomson AW. Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance. J Immunol. 2007 Jun 01; 178(11):7018-31.
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Bray RA, Nolen JD, Larsen C, Pearson T, Newell KA, Kokko K, Guasch A, Tso P, Mendel JB, Gebel HM. Transplanting the highly sensitized patient: The emory algorithm. Am J Transplant. 2006 Oct; 6(10):2307-15.
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Bryan CF, Harrell KM, Mitchell SI, Warady BA, Aeder MI, Luger AM, Murillo D, Muruve NA, Nelson PW, Shield CF. HLA points assigned in cadaveric kidney allocation should be revisited: an analysis of HLA class II molecularly typed patients and donors. Am J Transplant. 2003 Apr; 3(4):459-64.
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Laaksonen M, Pastinen T, Sj?roos M, Kuokkanen S, Ruutiainen J, Sumelahti ML, Reijonen H, Salonen R, Wikstr?m J, Panelius M, Partanen J, Tienari PJ, Ilonen J. HLA class II associated risk and protection against multiple sclerosis-a Finnish family study. J Neuroimmunol. 2002 Jan; 122(1-2):140-5.
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Winer S, Gunaratnam L, Astsatourov I, Cheung RK, Kubiak V, Karges W, Hammond-McKibben D, Gaedigk R, Graziano D, Trucco M, Becker DJ, Dosch HM. Peptide dose, MHC affinity, and target self-antigen expression are critical for effective immunotherapy of nonobese diabetic mouse prediabetes. J Immunol. 2000 Oct 01; 165(7):4086-94.
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Bryan CF, Harrell K, Aeder MI, Luger AM, Nelson PW, Pierce GE, Ross G, Shield CF, Warady BA. Impact of HLA DR typing by polymerase chain reaction amplification with DR beta 1 sequence-specific primers on cadaveric renal allocation. Transplant Proc. 1993 Dec; 25(6):3060-3.
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