Valproic Acid
"Valproic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A fatty acid with anticonvulsant properties used in the treatment of epilepsy. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of voltage dependent sodium channels.
Descriptor ID |
D014635
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MeSH Number(s) |
D02.241.081.944.509.900 D10.251.400.895.593.900
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Concept/Terms |
Valproic Acid- Valproic Acid
- Acid, Valproic
- Divalproex
- Propylisopropylacetic Acid
- Acid, Propylisopropylacetic
- 2-Propylpentanoic Acid
- 2 Propylpentanoic Acid
Divalproex Sodium- Divalproex Sodium
- Sodium, Divalproex
- Valproic Acid, Sodium Salt (2:1)
- Semisodium Valproate
- Valproate, Semisodium
Valproate Sodium- Valproate Sodium
- Sodium, Valproate
- Sodium Valproate
- Valproate, Sodium
Calcium Valproate- Calcium Valproate
- Valproate, Calcium
- Valproate Calcium
- Calcium, Valproate
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Below are MeSH descriptors whose meaning is more general than "Valproic Acid".
Below are MeSH descriptors whose meaning is more specific than "Valproic Acid".
This graph shows the total number of publications written about "Valproic Acid" by people in this website by year, and whether "Valproic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2011 | 1 | 0 | 1 | 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Valproic Acid" by people in Profiles.
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Ghodke-Puranik Y, Thorn CF, Lamba JK, Leeder JS, Song W, Birnbaum AK, Altman RB, Klein TE. Valproic acid pathway: pharmacokinetics and pharmacodynamics. Pharmacogenet Genomics. 2013 Apr; 23(4):236-41.
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Price KE, Pearce RE, Garg UC, Heese BA, Smith LD, Sullivan JE, Kennedy MJ, Bale JF, Ward RM, Chang TK, Abbott FS, Leeder JS. Effects of valproic acid on organic acid metabolism in children: a metabolic profiling study. Clin Pharmacol Ther. 2011 Jun; 89(6):867-74.
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Wu S, Legido A, De Luca F. Effects of valproic acid on longitudinal bone growth. J Child Neurol. 2004 Jan; 19(1):26-30.
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Wasserman GS, Aldridge SC, Kelly JC, Abdel-Rahman SM. A unique valproic acid ingestion. J Toxicol Clin Toxicol. 2001; 39(4):419-22.
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