 Pteroylpolyglutamic Acids
"Pteroylpolyglutamic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Derivatives of folic acid (pteroylglutamic acid). In gamma-glutamyl linkage they are found in many tissues. They are converted to folic acid by the action of pteroylpolyglutamate hydrolase or synthesized from folic acid by the action of folate polyglutamate synthetase. Synthetic pteroylpolyglutamic acids, which are in alpha-glutamyl linkage, are active in bacterial growth assays.
| Descriptor ID |
D011624
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| MeSH Number(s) |
D03.438.733.631.400.600
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| Concept/Terms |
Folate Polyglutamates- Folate Polyglutamates
- Polyglutamates, Folate
- Pteroylpolyglutamates
- Polyglutamate Folates
- Folates, Polyglutamate
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Below are MeSH descriptors whose meaning is more general than "Pteroylpolyglutamic Acids".
Below are MeSH descriptors whose meaning is more specific than "Pteroylpolyglutamic Acids".
This graph shows the total number of publications written about "Pteroylpolyglutamic Acids" by people in this website by year, and whether "Pteroylpolyglutamic Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 2 | 0 | 2 | | 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pteroylpolyglutamic Acids" by people in Profiles.
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Funk RS, van Haandel L, Leeder JS, Becker ML. Folate depletion and increased glutamation in juvenile idiopathic arthritis patients treated with methotrexate. Arthritis Rheumatol. 2014 Dec; 66(12):3476-85.
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van Haandel L, Becker ML, Williams TD, Stobaugh JF, Leeder JS. Comprehensive quantitative measurement of folate polyglutamates in human erythrocytes by ion pairing ultra-performance liquid chromatography/tandem mass spectrometry. Rapid Commun Mass Spectrom. 2012 Jul 30; 26(14):1617-30.
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Becker ML, van Haandel L, Gaedigk R, Thomas B, Hoeltzel MF, Lasky A, Dai H, Stobaugh J, Leeder JS. Red blood cell folate concentrations and polyglutamate distribution in juvenile arthritis: predictors of folate variability. Pharmacogenet Genomics. 2012 Apr; 22(4):236-46.
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