 Phosphodiesterase Inhibitors
"Phosphodiesterase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds which inhibit or antagonize the biosynthesis or actions of phosphodiesterases.
| Descriptor ID |
D010726
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| MeSH Number(s) |
D27.505.519.389.735
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| Concept/Terms |
Phosphodiesterase Inhibitors- Phosphodiesterase Inhibitors
- Phosphodiesterase Antagonists
- Phosphoric Diester Hydrolase Inhibitors
- Antiphosphodiesterases
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Below are MeSH descriptors whose meaning is more general than "Phosphodiesterase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Phosphodiesterase Inhibitors".
This graph shows the total number of publications written about "Phosphodiesterase Inhibitors" by people in this website by year, and whether "Phosphodiesterase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phosphodiesterase Inhibitors" by people in Profiles.
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Khalsa SS, Victor TA, Kuplicki R, Yeh HW, Vanover KE, Paulus MP, Davis RE. Single doses of a highly selective inhibitor of phosphodiesterase 1 (lenrispodun) in healthy volunteers: a randomized pharmaco-fMRI clinical trial. Neuropsychopharmacology. 2022 09; 47(10):1844-1853.
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Neville KA, Szefler SJ, Abdel-Rahman SM, Lahu G, Zech K, Herzog R, Bethke TD, Gleason MC, Kearns GL. Single-dose pharmacokinetics of roflumilast in children and adolescents. J Clin Pharmacol. 2008 Aug; 48(8):978-85.
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Chainuvati S, Nafziger AN, Leeder JS, Gaedigk A, Kearns GL, Sellers E, Zhang Y, Kashuba AD, Rowland E, Bertino JS. Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5+1 cocktail". Clin Pharmacol Ther. 2003 Nov; 74(5):437-47.
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Suh BC, Park TJ, Kim KT. Synergistic activation of adenylyl cyclase is dependent upon phospholipase C-mediated processes in human neuroblastoma SK-N-BE(2)C cells. Eur J Pharmacol. 1996 Oct 24; 314(1-2):235-42.
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