 Folic Acid
"Folic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the vitamin B family that stimulates the hematopoietic system. It is present in the liver and kidney and is found in mushrooms, spinach, yeast, green leaves, and grasses (POACEAE). Folic acid is used in the treatment and prevention of folate deficiencies and megaloblastic anemia.
| Descriptor ID |
D005492
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| MeSH Number(s) |
D03.438.733.631.400
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| Concept/Terms |
Folic Acid- Folic Acid
- Vitamin B9
- B9, Vitamin
- Vitamin M
- Pteroylglutamic Acid
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Below are MeSH descriptors whose meaning is more general than "Folic Acid".
Below are MeSH descriptors whose meaning is more specific than "Folic Acid".
This graph shows the total number of publications written about "Folic Acid" by people in this website by year, and whether "Folic Acid" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2015 | 1 | 1 | 2 | | 2018 | 0 | 1 | 1 | | 2019 | 2 | 0 | 2 |
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Below are the most recent publications written about "Folic Acid" by people in Profiles.
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Maulik D, van Haandel L, Allsworth J, Chaisanguanthum KS, Yeast JD, Leeder JS. The effect of race and supplementation on maternal and umbilical cord plasma folates. J Matern Fetal Neonatal Med. 2021 Sep; 34(18):3057-3065.
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Chan D, Shao X, Dumargne MC, Aarabi M, Simon MM, Kwan T, Bailey JL, Robaire B, Kimmins S, San Gabriel MC, Zini A, Librach C, Moskovtsev S, Grundberg E, Bourque G, Pastinen T, Trasler JM. Customized MethylC-Capture Sequencing to Evaluate Variation in the Human Sperm DNA Methylome Representative of Altered Folate Metabolism. Environ Health Perspect. 2019 08; 127(8):87002.
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Singh RK, van Haandel L, Kiptoo P, Becker ML, Siahaan TJ, Funk RS. Methotrexate disposition, anti-folate activity and efficacy in the collagen-induced arthritis mouse model. Eur J Pharmacol. 2019 Jun 15; 853:264-274.
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Singh RK, van Haandel L, Heruth DP, Ye SQ, Leeder JS, Becker ML, Funk RS. Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP. J Pharmacol Exp Ther. 2018 04; 365(1):96-106.
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Majnik AV, Lane RH. The relationship between early-life environment, the epigenome and the microbiota. Epigenomics. 2015 Oct; 7(7):1173-84.
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Aarabi M, San Gabriel MC, Chan D, Behan NA, Caron M, Pastinen T, Bourque G, MacFarlane AJ, Zini A, Trasler J. High-dose folic acid supplementation alters the human sperm methylome and is influenced by the MTHFR C677T polymorphism. Hum Mol Genet. 2015 Nov 15; 24(22):6301-13.
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Funk RS, van Haandel L, Leeder JS, Becker ML. Folate depletion and increased glutamation in juvenile idiopathic arthritis patients treated with methotrexate. Arthritis Rheumatol. 2014 Dec; 66(12):3476-85.
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van Haandel L, Stobaugh JF. Folate determination in human health: UPLC-MS/MS is the emerging methodology of choice. Bioanalysis. 2013 Dec; 5(24):3023-31.
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Goldman J, Becker ML, Jones B, Clements M, Leeder JS. Development of biomarkers to optimize pediatric patient management: what makes children different? Biomark Med. 2011 Dec; 5(6):781-94.
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van Haandel L, Stobaugh JF. Bioanalytical method development for a generation 5 polyamidoamine folic acid methotrexate conjugated nanoparticle. Anal Bioanal Chem. 2010 Jul; 397(5):1841-52.
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