 Cytochrome P-450 Enzyme Inhibitors
"Cytochrome P-450 Enzyme Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs and compounds which inhibit or antagonize the biosynthesis or actions of CYTOCHROME P-450 ENZYMES.
| Descriptor ID |
D065607
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| MeSH Number(s) |
D27.505.389.500 D27.505.519.389.335
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| Concept/Terms |
Cytochrome P-450 Enzyme Inhibitors- Cytochrome P-450 Enzyme Inhibitors
- Cytochrome P 450 Enzyme Inhibitors
- P-450 Enzyme Inhibitors
- Enzyme Inhibitors, P-450
- Inhibitors, P-450 Enzyme
- P 450 Enzyme Inhibitors
- P450 Enzyme Inhibitors
- Enzyme Inhibitors, P450
- Inhibitors, P450 Enzyme
- Cytochrome P-450 Inhibitors
- Cytochrome P 450 Inhibitors
- Inhibitors, Cytochrome P-450
- P-450 Inhibitors, Cytochrome
Cytochrome P-450 Monooxygenase Inhibitors- Cytochrome P-450 Monooxygenase Inhibitors
- Cytochrome P 450 Monooxygenase Inhibitors
- Cytochrome P-450-Dependent Monooxygenase Inhibitors
- Cytochrome P 450 Dependent Monooxygenase Inhibitors
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Below are MeSH descriptors whose meaning is more general than "Cytochrome P-450 Enzyme Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Cytochrome P-450 Enzyme Inhibitors".
This graph shows the total number of publications written about "Cytochrome P-450 Enzyme Inhibitors" by people in this website by year, and whether "Cytochrome P-450 Enzyme Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 0 | 2 | 2 | | 2006 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Cytochrome P-450 Enzyme Inhibitors" by people in Profiles.
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Gomez L, Kovac JR, Lamb DJ. CYP17A1 inhibitors in castration-resistant prostate cancer. Steroids. 2015 Mar; 95:80-7.
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Parkinson A, Kazmi F, Buckley DB, Yerino P, Paris BL, Holsapple J, Toren P, Otradovec SM, Ogilvie BW. An evaluation of the dilution method for identifying metabolism-dependent inhibitors of cytochrome P450 enzymes. Drug Metab Dispos. 2011 Aug; 39(8):1370-87.
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Pearce RE, Leeder JS, Kearns GL. Biotransformation of fluticasone: in vitro characterization. Drug Metab Dispos. 2006 Jun; 34(6):1035-40.
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Kashuba AD, Nafziger AN, Kearns GL, Leeder JS, Gotschall R, Gaedigk A, Bertino JS. Limitations of dextromethorphan N-demethylation as a measure of CYP3A activity. Pharmacogenetics. 1999 Aug; 9(4):453-62.
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Ibeanu GC, Blaisdell J, Ferguson RJ, Ghanayem BI, Brosen K, Benhamou S, Bouchardy C, Wilkinson GR, Dayer P, Goldstein JA. A novel transversion in the intron 5 donor splice junction of CYP2C19 and a sequence polymorphism in exon 3 contribute to the poor metabolizer phenotype for the anticonvulsant drug S-mephenytoin. J Pharmacol Exp Ther. 1999 Aug; 290(2):635-40.
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Kashuba AD, Nafziger AN, Kearns GL, Leeder JS, Gotschall R, Rocci ML, Kulawy RW, Beck DJ, Bertino JS. Effect of fluvoxamine therapy on the activities of CYP1A2, CYP2D6, and CYP3A as determined by phenotyping. Clin Pharmacol Ther. 1998 Sep; 64(3):257-68.
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Pearce RE, Rodrigues AD, Goldstein JA, Parkinson A. Identification of the human P450 enzymes involved in lansoprazole metabolism. J Pharmacol Exp Ther. 1996 May; 277(2):805-16.
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