 rho-Associated Kinases
"rho-Associated Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of intracellular-signaling serine threonine kinases that bind to RHO GTP-BINDING PROTEINS. They were originally found to mediate the effects of rhoA GTP-BINDING PROTEIN on the formation of STRESS FIBERS and FOCAL ADHESIONS. Rho-associated kinases have specificity for a variety of substrates including MYOSIN-LIGHT-CHAIN PHOSPHATASE and LIM KINASES.
| Descriptor ID |
D054460
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| MeSH Number(s) |
D08.811.913.696.620.682.700.814 D12.644.360.590 D12.776.476.595
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| Concept/Terms |
rho-Associated Kinases- rho-Associated Kinases
- rho Associated Kinases
- ROK Kinase
- rho-Kinase
- rho Kinase
- ROCK Protein Kinases
- Protein Kinases, ROCK
- rho-Associated Coiled-Coil Kinase
- Coiled-Coil Kinase, rho-Associated
- rho Associated Coiled Coil Kinase
- rho-Associated Kinase
- rho Associated Kinase
rho-Associated Kinase 1- rho-Associated Kinase 1
- rho Associated Kinase 1
- ROCK-I Protein Kinase
- ROCK I Protein Kinase
- rho-Associated Kinase beta
- rho Associated Kinase beta
- rho-Associated Protein Kinase beta
- rho Associated Protein Kinase beta
- p160ROCK
- rho-Associated Coiled-Coil Containing Protein Kinase 1
- rho Associated Coiled Coil Containing Protein Kinase 1
rho-Associated Kinase 2- rho-Associated Kinase 2
- rho Associated Kinase 2
- ROCK-II Protein Kinase
- ROCK II Protein Kinase
- rho-Associated Kinase alpha
- rho Associated Kinase alpha
- rho-Associated Protein Kinase alpha
- rho Associated Protein Kinase alpha
- p160 rhoA-Binding Kinase ROKalpha
- p160 rhoA Binding Kinase ROKalpha
- rho-Associated Coiled-Coil Containing Protein Kinase 2
- rho Associated Coiled Coil Containing Protein Kinase 2
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Below are MeSH descriptors whose meaning is more general than "rho-Associated Kinases".
Below are MeSH descriptors whose meaning is more specific than "rho-Associated Kinases".
This graph shows the total number of publications written about "rho-Associated Kinases" by people in this website by year, and whether "rho-Associated Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "rho-Associated Kinases" by people in Profiles.
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Wen Q, Goldenson B, Silver SJ, Schenone M, Dancik V, Huang Z, Wang LZ, Lewis TA, An WF, Li X, Bray MA, Thiollier C, Diebold L, Gilles L, Vokes MS, Moore CB, Bliss-Moreau M, Verplank L, Tolliday NJ, Mishra R, Vemula S, Shi J, Wei L, Kapur R, Lopez CK, Gerby B, Ballerini P, Pflumio F, Gilliland DG, Goldberg L, Birger Y, Izraeli S, Gamis AS, Smith FO, Woods WG, Taub J, Scherer CA, Bradner JE, Goh BC, Mercher T, Carpenter AE, Gould RJ, Clemons PA, Carr SA, Root DE, Schreiber SL, Stern AM, Crispino JD. Identification of regulators of polyploidization presents therapeutic targets for treatment of AMKL. Cell. 2012 Aug 03; 150(3):575-89.
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