 Dual-Specificity Phosphatases
"Dual-Specificity Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sub-class of protein tyrosine phosphatases that contain an additional phosphatase activity which cleaves phosphate ester bonds on SERINE or THREONINE residues that are located on the same protein.
| Descriptor ID |
D054637
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| MeSH Number(s) |
D08.811.277.352.650.625.225 D08.811.277.352.650.775.250 D08.811.641.755 D12.644.360.268 D12.776.476.268
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| Concept/Terms |
Dual-Specificity Phosphatases- Dual-Specificity Phosphatases
- Dual Specificity Phosphatases
- Phosphatases, Dual-Specificity
- Dual-Specificity Phosphatase
- Dual Specificity Phosphatase
- Phosphatase, Dual-Specificity
- DUSP Phosphatases
- Phosphatases, DUSP
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Below are MeSH descriptors whose meaning is more general than "Dual-Specificity Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "Dual-Specificity Phosphatases".
This graph shows the total number of publications written about "Dual-Specificity Phosphatases" by people in this website by year, and whether "Dual-Specificity Phosphatases" was a major or minor topic of these publications.
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Below are the most recent publications written about "Dual-Specificity Phosphatases" by people in Profiles.
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Ferguson BS, Wennersten SA, Demos-Davies KM, Rubino M, Robinson EL, Cavasin MA, Stratton MS, Kidger AM, Hu T, Keyse SM, McKnight RA, Lane RH, Nozik ES, Weiser-Evans MCM, McKinsey TA. DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy. Am J Physiol Heart Circ Physiol. 2021 08 01; 321(2):H382-H389.
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Habibian JS, Jefic M, Bagchi RA, Lane RH, McKnight RA, McKinsey TA, Morrison RF, Ferguson BS. DUSP5 functions as a feedback regulator of TNFa-induced ERK1/2 dephosphorylation and inflammatory gene expression in adipocytes. Sci Rep. 2017 10 10; 7(1):12879.
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Ke X, McKnight RA, Caprau D, O'Grady S, Fu Q, Yu X, Callaway CW, Albertine KH, Lane RH. Intrauterine growth restriction affects hippocampal dual specificity phosphatase 5 gene expression and epigenetic characteristics. Physiol Genomics. 2011 Oct 20; 43(20):1160-9.
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Fu Q, McKnight RA, Yu X, Callaway CW, Lane RH. Growth retardation alters the epigenetic characteristics of hepatic dual specificity phosphatase 5. FASEB J. 2006 Oct; 20(12):2127-9.
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