 Tandem Mass Spectrometry
"Tandem Mass Spectrometry" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometry technique using two (MS/MS) or more mass analyzers. With two in tandem, the precursor ions are mass-selected by a first mass analyzer, and focused into a collision region where they are then fragmented into product ions which are then characterized by a second mass analyzer. A variety of techniques are used to separate the compounds, ionize them, and introduce them to the first mass analyzer. For example, for in GC-MS/MS, GAS CHROMATOGRAPHY-MASS SPECTROMETRY is involved in separating relatively small compounds by GAS CHROMATOGRAPHY prior to injecting them into an ionization chamber for the mass selection.
| Descriptor ID |
D053719
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| MeSH Number(s) |
E05.196.566.880
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| Concept/Terms |
Tandem Mass Spectrometry- Tandem Mass Spectrometry
- Mass Spectrometry, Tandem
- Mass Spectrometry-Mass Spectrometry
- Mass Spectrometry Mass Spectrometry
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Below are MeSH descriptors whose meaning is more general than "Tandem Mass Spectrometry".
Below are MeSH descriptors whose meaning is more specific than "Tandem Mass Spectrometry".
This graph shows the total number of publications written about "Tandem Mass Spectrometry" by people in this website by year, and whether "Tandem Mass Spectrometry" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 1 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 2 | 1 | 3 | | 2013 | 1 | 0 | 1 | | 2014 | 0 | 2 | 2 | | 2015 | 0 | 1 | 1 | | 2016 | 8 | 1 | 9 | | 2017 | 1 | 1 | 2 | | 2018 | 3 | 0 | 3 | | 2019 | 0 | 2 | 2 | | 2020 | 1 | 0 | 1 | | 2022 | 4 | 4 | 8 | | 2023 | 0 | 1 | 1 | | 2024 | 4 | 0 | 4 | | 2025 | 1 | 0 | 1 |
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Below are the most recent publications written about "Tandem Mass Spectrometry" by people in Profiles.
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Garg U, Ramoo B, Frazee C, Dasgupta A. Technical Note: Comparison of Plain and Serum-Separator Blood Collection Tubes for the Measurement of Steroid Hormones by Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS): Observation of Erroneous Peaks in Serum Separator Tubes for Analysis of Testosterone and Dehydroepiandrosterone. Ann Clin Lab Sci. 2025 May; 55(3):449-452.
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Thakur A, Yue G, Ahire D, Mettu VS, Al Maghribi A, Ford K, Peixoto L, Leeder JS, Prasad B. Sex and the Kidney Drug-Metabolizing Enzymes and Transporters: Are Preclinical Drug Disposition Data Translatable to Humans? Clin Pharmacol Ther. 2024 Jul; 116(1):235-246.
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Dasgupta A, Woodard K, Ramoo B, Frazee C, Garg U. Technical Note: Significant Positive Bias in Lower Concentrations but Negative Bias in Higher Concentrations in Testosterone Measurement Using Beckman Access Immunoassay Compared to a Liquid Chromatography-Tandem Mass Spectrometry Reference Method. Ann Clin Lab Sci. 2024 Mar; 54(2):258-261.
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Garg U, Munar A, Clinton Frazee C. Liquid Chromatography-Tandem Mass Spectrometry Method for the Quantification of Plasma Busulfan. Methods Mol Biol. 2024; 2737:133-140.
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Shell S, Clinton Frazee C, Garg U. Quantification of Fentanyl and Norfentanyl in Whole Blood Using Liquid Chromatography-Tandem Mass Spectrometry. Methods Mol Biol. 2024; 2737:275-282.
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Garg U, Munar A, Frazee C. Quantitation of Mycophenolic Acid and Mycophenolic Acid Glucuronide in Serum or Plasma by LC-MS/MS. Curr Protoc. 2023 Apr; 3(4):e730.
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Tessman RT, Nolte W, Toren P, Gibson K, Vu L, Goldman J. Simultaneous quantification of trimethoprim metabolites in pediatric plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 May 15; 1198:123232.
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Zhang YV, Garg U. Introduction to Mass Spectrometry for Bimolecular Analysis in a Clinical Laboratory. Methods Mol Biol. 2022; 2546:1-12.
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Scott D, Clinton Frazee C, Heese B, Garg U. Tandem Mass Spectrometry for the Analysis of Plasma/Serum Acylcarnitines for the Diagnosis of Certain Organic Acidurias and Fatty Acid Oxidation Disorders. Methods Mol Biol. 2022; 2546:27-34.
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Baird S, Frazee CC, Garg U. Quantification of Free and Total Carnitine in Serum Using Liquid Chromatography Tandem Mass Spectrometry. Methods Mol Biol. 2022; 2546:95-104.
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