 Proto-Oncogene Proteins c-fos
"Proto-Oncogene Proteins c-fos" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.
| Descriptor ID |
D016760
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| MeSH Number(s) |
D12.776.260.108.765 D12.776.624.664.700.179 D12.776.660.760 D12.776.930.127.765
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| Concept/Terms |
Proto-Oncogene Proteins c-fos- Proto-Oncogene Proteins c-fos
- Proto Oncogene Proteins c fos
- fos Proto-Oncogene Proteins
- fos Proto Oncogene Proteins
- Proto-Oncogene Proteins fos
- Proto Oncogene Proteins fos
- p55(c-fos)
- Proto-Oncogene Products c-fos
- Proto Oncogene Products c fos
- c-fos Proteins
- c fos Proteins
- p55 c-fos
- p55 c fos
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-fos".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-fos".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-fos" by people in this website by year, and whether "Proto-Oncogene Proteins c-fos" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1990 | 1 | 11 | 12 | | 1991 | 2 | 6 | 8 | | 1992 | 3 | 0 | 3 | | 1993 | 7 | 2 | 9 | | 1994 | 6 | 2 | 8 | | 1995 | 3 | 1 | 4 | | 1996 | 4 | 0 | 4 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-fos" by people in Profiles.
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Petty WJ, Li N, Biddle A, Bounds R, Nitkin C, Ma Y, Dragnev KH, Freemantle SJ, Dmitrovsky E. A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis. J Natl Cancer Inst. 2005 Nov 16; 97(22):1645-51.
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Ordway JM, Eberhart D, Curran T. Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding. Mol Cell Biol. 2003 Jun; 23(12):4257-66.
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Bakin AV, Curran T. Role of DNA 5-methylcytosine transferase in cell transformation by fos. Science. 1999 Jan 15; 283(5400):387-90.
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Vendrell M, Curran T, Morgan JI. A gene expression approach to mapping the functional maturation of the hippocampus. Brain Res Mol Brain Res. 1998 Dec 10; 63(1):25-34.
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Kerppola TK, Curran T. The transcription activation domains of Fos and Jun induce DNA bending through electrostatic interactions. EMBO J. 1997 May 15; 16(10):2907-16.
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Kasof GM, Smeyne RJ, Curran T, Morgan JI. Developmental expression of Fos-lacZ in the brains of postnatal transgenic rats. Brain Res Dev Brain Res. 1996 May 31; 93(1-2):191-7.
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Martin ML, Lieberman PM, Curran T. Fos-Jun dimerization promotes interaction of the basic region with TFIIE-34 and TFIIF. Mol Cell Biol. 1996 May; 16(5):2110-8.
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Chen RH, Juo PC, Curran T, Blenis J. Phosphorylation of c-Fos at the C-terminus enhances its transforming activity. Oncogene. 1996 Apr 04; 12(7):1493-502.
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Hermida-Matsumoto ML, Chock PB, Curran T, Yang DC. Ubiquitinylation of transcription factors c-Jun and c-Fos using reconstituted ubiquitinylating enzymes. J Biol Chem. 1996 Mar 01; 271(9):4930-6.
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Kasof GM, Mandelzys A, Maika SD, Hammer RE, Curran T, Morgan JI. Kainic acid-induced neuronal death is associated with DNA damage and a unique immediate-early gene response in c-fos-lacZ transgenic rats. J Neurosci. 1995 Jun; 15(6):4238-49.
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