 Proto-Oncogene Proteins c-fos
"Proto-Oncogene Proteins c-fos" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the c-fos genes (GENES, FOS). They are involved in growth-related transcriptional control. c-fos combines with c-jun (PROTO-ONCOGENE PROTEINS C-JUN) to form a c-fos/c-jun heterodimer (TRANSCRIPTION FACTOR AP-1) that binds to the TRE (TPA-responsive element) in promoters of certain genes.
| Descriptor ID |
D016760
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| MeSH Number(s) |
D12.776.260.108.765 D12.776.624.664.700.179 D12.776.660.760 D12.776.930.127.765
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| Concept/Terms |
Proto-Oncogene Proteins c-fos- Proto-Oncogene Proteins c-fos
- Proto Oncogene Proteins c fos
- fos Proto-Oncogene Proteins
- fos Proto Oncogene Proteins
- Proto-Oncogene Proteins fos
- Proto Oncogene Proteins fos
- p55(c-fos)
- Proto-Oncogene Products c-fos
- Proto Oncogene Products c fos
- c-fos Proteins
- c fos Proteins
- p55 c-fos
- p55 c fos
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-fos".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-fos".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-fos" by people in this website by year, and whether "Proto-Oncogene Proteins c-fos" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1993 | 7 | 2 | 9 | | 1994 | 6 | 2 | 8 | | 1995 | 3 | 1 | 4 | | 1996 | 4 | 0 | 4 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 1 | 0 | 1 | | 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-fos" by people in Profiles.
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Dai C, Rennhack JP, Arnoff TE, Thaker M, Younger ST, Doench JG, Huang AY, Yang A, Aguirre AJ, Wang B, Mun E, O'Connell JT, Huang Y, Labella K, Talamas JA, Li J, Ilic N, Hwang J, Hong AL, Giacomelli AO, Gjoerup O, Root DE, Hahn WC. SMAD4 represses FOSL1 expression and pancreatic cancer metastatic colonization. Cell Rep. 2021 07 27; 36(4):109443.
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Nitkin CR, Xia S, Menden H, Yu W, Xiong M, Heruth DP, Ye SQ, Sampath V. FOSL1 is a novel mediator of endotoxin/lipopolysaccharide-induced pulmonary angiogenic signaling. Sci Rep. 2020 08 04; 10(1):13143.
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Petty WJ, Li N, Biddle A, Bounds R, Nitkin C, Ma Y, Dragnev KH, Freemantle SJ, Dmitrovsky E. A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis. J Natl Cancer Inst. 2005 Nov 16; 97(22):1645-51.
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Ordway JM, Eberhart D, Curran T. Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding. Mol Cell Biol. 2003 Jun; 23(12):4257-66.
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Bakin AV, Curran T. Role of DNA 5-methylcytosine transferase in cell transformation by fos. Science. 1999 Jan 15; 283(5400):387-90.
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Vendrell M, Curran T, Morgan JI. A gene expression approach to mapping the functional maturation of the hippocampus. Brain Res Mol Brain Res. 1998 Dec 10; 63(1):25-34.
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Kerppola TK, Curran T. The transcription activation domains of Fos and Jun induce DNA bending through electrostatic interactions. EMBO J. 1997 May 15; 16(10):2907-16.
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Kasof GM, Smeyne RJ, Curran T, Morgan JI. Developmental expression of Fos-lacZ in the brains of postnatal transgenic rats. Brain Res Dev Brain Res. 1996 May 31; 93(1-2):191-7.
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Martin ML, Lieberman PM, Curran T. Fos-Jun dimerization promotes interaction of the basic region with TFIIE-34 and TFIIF. Mol Cell Biol. 1996 May; 16(5):2110-8.
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Chen RH, Juo PC, Curran T, Blenis J. Phosphorylation of c-Fos at the C-terminus enhances its transforming activity. Oncogene. 1996 Apr 04; 12(7):1493-502.
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