 Isoenzymes
"Isoenzymes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Structurally related forms of an enzyme. Each isoenzyme has the same mechanism and classification, but differs in its chemical, physical, or immunological characteristics.
| Descriptor ID |
D007527
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| MeSH Number(s) |
D08.811.348 D12.776.800.300
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Isoenzymes".
Below are MeSH descriptors whose meaning is more specific than "Isoenzymes".
This graph shows the total number of publications written about "Isoenzymes" by people in this website by year, and whether "Isoenzymes" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 | | 1997 | 0 | 1 | 1 | | 1998 | 2 | 1 | 3 | | 1999 | 4 | 0 | 4 | | 2000 | 1 | 1 | 2 | | 2001 | 0 | 1 | 1 | | 2003 | 0 | 1 | 1 | | 2007 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2016 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Isoenzymes" by people in Profiles.
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Rentea RM, Rentea MJ, Biesterveld B, Liedel JL, Gourlay DM. Factors Known to Influence the Development of Necrotizing Enterocolitis to Modify Expression and Activity of Intestinal Alkaline Phosphatase in a Newborn Neonatal Rat Model. Eur J Pediatr Surg. 2019 Jun; 29(3):290-297.
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Bhatt DK, Gaedigk A, Pearce RE, Leeder JS, Prasad B. Age-dependent Protein Abundance of Cytosolic Alcohol and Aldehyde Dehydrogenases in Human Liver. Drug Metab Dispos. 2017 09; 45(9):1044-1048.
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Dinh JC, Pearce RE, Van Haandel L, Gaedigk A, Leeder JS. Characterization of Atomoxetine Biotransformation and Implications for Development of PBPK Models for Dose Individualization in Children. Drug Metab Dispos. 2016 07; 44(7):1070-9.
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Menden H, Tate E, Hogg N, Sampath V. LPS-mediated endothelial activation in pulmonary endothelial cells: role of Nox2-dependent IKK-? phosphorylation. Am J Physiol Lung Cell Mol Physiol. 2013 Mar 15; 304(6):L445-55.
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Sugamori KS, Brenneman D, Wong S, Gaedigk A, Yu V, Abramovici H, Rozmahel R, Grant DM. Effect of arylamine acetyltransferase Nat3 gene knockout on N-acetylation in the mouse. Drug Metab Dispos. 2007 Jul; 35(7):1064-70.
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Sugamori KS, Wong S, Gaedigk A, Yu V, Abramovici H, Rozmahel R, Grant DM. Generation and functional characterization of arylamine N-acetyltransferase Nat1/Nat2 double-knockout mice. Mol Pharmacol. 2003 Jul; 64(1):170-9.
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Pearce RE, Gotschall RR, Kearns GL, Leeder JS. Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms. Drug Metab Dispos. 2001 Dec; 29(12):1548-54.
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McKenzie FR, Connelly MA, Balzarano D, M?ller JR, Geleziunas R, Marcu KB. Functional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirements. Mol Cell Biol. 2000 Apr; 20(8):2635-49.
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Windmill KF, Gaedigk A, Hall PM, Samaratunga H, Grant DM, McManus ME. Localization of N-acetyltransferases NAT1 and NAT2 in human tissues. Toxicol Sci. 2000 Mar; 54(1):19-29.
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de Wildt SN, Kearns GL, Leeder JS, van den Anker JN. Cytochrome P450 3A: ontogeny and drug disposition. Clin Pharmacokinet. 1999 Dec; 37(6):485-505.
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