 Erythromycin
"Erythromycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits. This binding process inhibits peptidyl transferase activity and interferes with translocation of amino acids during translation and assembly of proteins.
| Descriptor ID |
D004917
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| MeSH Number(s) |
D02.540.576.500.992
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Erythromycin".
Below are MeSH descriptors whose meaning is more specific than "Erythromycin".
This graph shows the total number of publications written about "Erythromycin" by people in this website by year, and whether "Erythromycin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2007 | 1 | 1 | 2 |
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Below are the most recent publications written about "Erythromycin" by people in Profiles.
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Kang P, Liao M, Wester MR, Leeder JS, Pearce RE, Correia MA. CYP3A4-Mediated carbamazepine (CBZ) metabolism: formation of a covalent CBZ-CYP3A4 adduct and alteration of the enzyme kinetic profile. Drug Metab Dispos. 2008 Mar; 36(3):490-9.
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Bogdanovich T, Aydin N, Chavez-Bueno S, McCracken G, Bozdogan B, Appelbaum PC. Genetic characterization of erythromycin- and methicillin-resistant community-acquired Staphylococcus aureus isolated from children in Texas. Diagn Microbiol Infect Dis. 2007 Oct; 59(2):231-3.
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R?os AM, Mej?as A, Ch?vez-Bueno S, Fonseca-Aten M, Katz K, Hatfield J, G?mez AM, Jafri HS, McCracken GH, Ramilo O, Hardy RD. Impact of cethromycin (ABT-773) therapy on microbiological, histologic, immunologic, and respiratory indices in a murine model of Mycoplasma pneumoniae lower respiratory infection. Antimicrob Agents Chemother. 2004 Aug; 48(8):2897-904.
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Wintermeyer SM, Abdel-Rahman SM, Nahata MC. Dirithromycin: a new macrolide. Ann Pharmacother. 1996 Oct; 30(10):1141-9.
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Lantos J. Transfer of erythromycin resistance in Staphylococcus aureus. Acta Microbiol Acad Sci Hung. 1977; 24(2):107-13.
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