Complement C8
"Complement C8" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 150-kDa serum glycoprotein composed of three subunits with each encoded by a different gene (C8A; C8B; and C8G). This heterotrimer contains a disulfide-linked C8alpha-C8gamma heterodimer and a noncovalently associated C8beta chain. C8 is the next component to bind the C5-7 complex forming C5b-8 that binds COMPLEMENT C9 and acts as a catalyst in the polymerization of C9.
| Descriptor ID |
D003185
|
| MeSH Number(s) |
D12.776.124.486.274.750
|
| Concept/Terms |
Complement C8- Complement C8
- C8, Complement
- Complement Component 8
- Component 8, Complement
- C8 Complement
- Complement, C8
- Complement 8
|
Below are MeSH descriptors whose meaning is more general than "Complement C8".
Below are MeSH descriptors whose meaning is more specific than "Complement C8".
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