 Complement C3
"Complement C3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycoprotein that is central in both the classical and the alternative pathway of COMPLEMENT ACTIVATION. C3 can be cleaved into COMPLEMENT C3A and COMPLEMENT C3B, spontaneously at low level or by C3 CONVERTASE at high level. The smaller fragment C3a is an ANAPHYLATOXIN and mediator of local inflammatory process. The larger fragment C3b binds with C3 convertase to form C5 convertase.
| Descriptor ID |
D003176
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| MeSH Number(s) |
D12.776.124.050.140 D12.776.124.486.274.250
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| Concept/Terms |
Complement C3- Complement C3
- C3, Complement
- Complement 3
- Complement Component 3
- Component 3, Complement
- C3 Complement
- Complement, C3
Complement C3 Precursor- Complement C3 Precursor
- C3 Precursor, Complement
- Precursor, Complement C3
- Pro-C3
- Pro C3
- Precursor-Complement 3
- Precursor Complement 3
- Pro-Complement 3
- Pro Complement 3
- C3 Precursor
- Precursor, C3
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Below are MeSH descriptors whose meaning is more general than "Complement C3".
Below are MeSH descriptors whose meaning is more specific than "Complement C3".
This graph shows the total number of publications written about "Complement C3" by people in this website by year, and whether "Complement C3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "Complement C3" by people in Profiles.
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Ryu E, Fridley BL, Tosakulwong N, Bailey KR, Edwards AO. Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study. Mol Vis. 2010 Dec 17; 16:2811-21.
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Park KH, Fridley BL, Ryu E, Tosakulwong N, Edwards AO. Complement component 3 (C3) haplotypes and risk of advanced age-related macular degeneration. Invest Ophthalmol Vis Sci. 2009 Jul; 50(7):3386-93.
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Srivastava T, Alon US. Pneumonia-associated acute glomerulonephritis. Clin Nephrol. 2002 Mar; 57(3):175-82.
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