Calpain

"Calpain" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cysteine proteinase found in many tissues. Hydrolyzes a variety of endogenous proteins including NEUROPEPTIDES; CYTOSKELETAL PROTEINS; proteins from SMOOTH MUSCLE; CARDIAC MUSCLE; liver; platelets; and erythrocytes. Two subclasses having high and low calcium sensitivity are known. Removes Z-discs and M-lines from myofibrils. Activates phosphorylase kinase and cyclic nucleotide-independent protein kinase. This enzyme was formerly listed as EC 3.4.22.4.

Descriptor ID	D002154
MeSH Number(s)	D08.811.277.656.262.500.120 D08.811.277.656.300.200.120
Concept/Terms	Calpain Calpain Calcium-Activated Protease Calcium Activated Protease Protease, Calcium-Activated Calcium-Dependent Neutral Proteinase Calcium Dependent Neutral Proteinase Neutral Proteinase, Calcium-Dependent Proteinase, Calcium-Dependent Neutral Calcium-Dependent Neutral Protease Calcium Dependent Neutral Protease Neutral Protease, Calcium-Dependent Protease, Calcium-Dependent Neutral Desminase Ca2+-Activated Protease Ca2+ Activated Protease Protease, Ca2+-Activated Calcium-Activated Neutral Proteinase Calcium Activated Neutral Proteinase Neutral Proteinase, Calcium-Activated Proteinase, Calcium-Activated Neutral Calcium-Activated Neutral Protease Calcium Activated Neutral Protease Neutral Protease, Calcium-Activated Protease, Calcium-Activated Neutral Calpain II Calpain II II, Calpain Calpain I Calpain I I, Calpain

Below are MeSH descriptors whose meaning is more general than "Calpain".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Peptide Hydrolases [D08.811.277.656]
Cysteine Proteases [D08.811.277.656.262]
Cysteine Endopeptidases [D08.811.277.656.262.500]
Calpain [D08.811.277.656.262.500.120]
Endopeptidases [D08.811.277.656.300]
Cysteine Endopeptidases [D08.811.277.656.300.200]
Calpain [D08.811.277.656.300.200.120]

Below are MeSH descriptors whose meaning is related to "Calpain".

Below are MeSH descriptors whose meaning is more specific than "Calpain".

publications

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