Cyclic Nucleotide Phosphodiesterases, Type 5

"Cyclic Nucleotide Phosphodiesterases, Type 5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cyclic nucleotide phosphodiesterase subfamily that is highly specific for CYCLIC GMP. It is found predominantly in vascular tissue and plays an important role in regulating VASCULAR SMOOTH MUSCLE contraction.

Descriptor ID	D054706
MeSH Number(s)	D08.811.277.352.640.150.500 D08.811.277.352.640.155.500 D12.644.360.008.500 D12.644.360.009.500 D12.776.476.008.500 D12.776.476.009.500
Concept/Terms	Cyclic Nucleotide Phosphodiesterases, Type 5 Cyclic Nucleotide Phosphodiesterases, Type 5 Phosphodiesterase-5 Phosphodiesterase 5 Phosphodiesterase V cGMP-Binding, cGMP-Specific 3',5'-cyclic Nucleotide Phosphodiesterase PDE5 Phosphodiesterases Phosphodiesterases, PDE5

Below are MeSH descriptors whose meaning is more general than "Cyclic Nucleotide Phosphodiesterases, Type 5".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Phosphoric Diester Hydrolases [D08.811.277.352.640]
3',5'-Cyclic-AMP Phosphodiesterases [D08.811.277.352.640.150]
Cyclic Nucleotide Phosphodiesterases, Type 5 [D08.811.277.352.640.150.500]
3',5'-Cyclic-GMP Phosphodiesterases [D08.811.277.352.640.155]
Cyclic Nucleotide Phosphodiesterases, Type 5 [D08.811.277.352.640.155.500]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
3',5'-Cyclic-AMP Phosphodiesterases [D12.644.360.008]
Cyclic Nucleotide Phosphodiesterases, Type 5 [D12.644.360.008.500]
3',5'-Cyclic-GMP Phosphodiesterases [D12.644.360.009]
Cyclic Nucleotide Phosphodiesterases, Type 5 [D12.644.360.009.500]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
3',5'-Cyclic-AMP Phosphodiesterases [D12.776.476.008]
Cyclic Nucleotide Phosphodiesterases, Type 5 [D12.776.476.008.500]
3',5'-Cyclic-GMP Phosphodiesterases [D12.776.476.009]
Cyclic Nucleotide Phosphodiesterases, Type 5 [D12.776.476.009.500]

Below are MeSH descriptors whose meaning is related to "Cyclic Nucleotide Phosphodiesterases, Type 5".

Below are MeSH descriptors whose meaning is more specific than "Cyclic Nucleotide Phosphodiesterases, Type 5".

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