Protein Tyrosine Phosphatase, Non-Receptor Type 22

"Protein Tyrosine Phosphatase, Non-Receptor Type 22" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of an N-terminal catalytic domain and a C-terminal PROLINE-rich domain. The phosphatase subtype is predominantly expressed in LYMPHOCYTES and plays a key role in the inhibition of downstream T-LYMPHOCYTE activation. Polymorphisms in the gene that encodes this phosphatase subtype are associated with a variety of AUTOIMMUNE DISEASES.

Descriptor ID	D054596
MeSH Number(s)	D08.811.277.352.650.775.300.930 D12.644.360.585.930 D12.776.476.564.930
Concept/Terms	Protein Tyrosine Phosphatase, Non-Receptor Type 22 Protein Tyrosine Phosphatase, Non-Receptor Type 22 Protein Tyrosine Phosphatase, Non Receptor Type 22 Protein-Tyrosine Phosphatase Lyp Protein Tyrosine Phosphatase Lyp Tyrosine Protein Phosphatase, Non-Receptor Type 22 Tyrosine Protein Phosphatase, Non Receptor Type 22 Lymphoid Phosphatase PTPase Lyp Lyp1 PTPase Lyp1 PTPase PTPase, Lyp1 Lyp2 PTPase Lyp2 PTPase PTPase, Lyp2

Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 22".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Phosphoric Monoester Hydrolases [D08.811.277.352.650]
Protein Tyrosine Phosphatases [D08.811.277.352.650.775]
Protein Tyrosine Phosphatases, Non-Receptor [D08.811.277.352.650.775.300]
Protein Tyrosine Phosphatase, Non-Receptor Type 22 [D08.811.277.352.650.775.300.930]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Protein Tyrosine Phosphatases, Non-Receptor [D12.644.360.585]
Protein Tyrosine Phosphatase, Non-Receptor Type 22 [D12.644.360.585.930]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Protein Tyrosine Phosphatases, Non-Receptor [D12.776.476.564]
Protein Tyrosine Phosphatase, Non-Receptor Type 22 [D12.776.476.564.930]

Below are MeSH descriptors whose meaning is related to "Protein Tyrosine Phosphatase, Non-Receptor Type 22".

Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 22".

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