Protein Tyrosine Phosphatase, Non-Receptor Type 12

"Protein Tyrosine Phosphatase, Non-Receptor Type 12" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION.

Descriptor ID	D054594
MeSH Number(s)	D08.811.277.352.650.775.300.850 D12.644.360.585.850 D12.776.476.564.850
Concept/Terms	Protein Tyrosine Phosphatase, Non-Receptor Type 12 Protein Tyrosine Phosphatase, Non-Receptor Type 12 Protein Tyrosine Phosphatase, Non Receptor Type 12 PTP-PEST PEST-Enriched Phosphatase PEST Enriched Phosphatase Phosphatase, PEST-Enriched PEP Protein Tyrosine Phosphatase PEP PTPase PTPase, PEP

Below are MeSH descriptors whose meaning is more general than "Protein Tyrosine Phosphatase, Non-Receptor Type 12".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Esterases [D08.811.277.352]
Phosphoric Monoester Hydrolases [D08.811.277.352.650]
Protein Tyrosine Phosphatases [D08.811.277.352.650.775]
Protein Tyrosine Phosphatases, Non-Receptor [D08.811.277.352.650.775.300]
Protein Tyrosine Phosphatase, Non-Receptor Type 12 [D08.811.277.352.650.775.300.850]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Protein Tyrosine Phosphatases, Non-Receptor [D12.644.360.585]
Protein Tyrosine Phosphatase, Non-Receptor Type 12 [D12.644.360.585.850]
Proteins [D12.776]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Protein Tyrosine Phosphatases, Non-Receptor [D12.776.476.564]
Protein Tyrosine Phosphatase, Non-Receptor Type 12 [D12.776.476.564.850]

Below are MeSH descriptors whose meaning is related to "Protein Tyrosine Phosphatase, Non-Receptor Type 12".

Below are MeSH descriptors whose meaning is more specific than "Protein Tyrosine Phosphatase, Non-Receptor Type 12".

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