Ghrelin
"Ghrelin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 28-amino acid, acylated, orexigenic peptide that is a ligand for GROWTH HORMONE SECRETAGOGUE RECEPTORS. Ghrelin is widely expressed but primarily in the stomach in the adults. Ghrelin acts centrally to stimulate growth hormone secretion and food intake, and peripherally to regulate energy homeostasis. Its large precursor protein, known as appetite-regulating hormone or motilin-related peptide, contains ghrelin and obestatin.
Descriptor ID |
D054439
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MeSH Number(s) |
D06.472.699.301 D12.644.548.322
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Concept/Terms |
GHRL Protein- GHRL Protein
- Ppghrelin
- Ghrelin-Obestatin Preprohormone
- Ghrelin Obestatin Preprohormone
- Motilin-Related Peptide Precursor
- Motilin Related Peptide Precursor
- Peptide Precursor, Motilin-Related
- Precursor, Motilin-Related Peptide
- PpMTLRP
- Ghrelin Precursor
- Precursor, Ghrelin
Appetite-Regulating Hormone- Appetite-Regulating Hormone
- Appetite Regulating Hormone
- Motilin-Related Peptide
- Motilin Related Peptide
- Gastric MLTRP
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Below are MeSH descriptors whose meaning is more general than "Ghrelin".
Below are MeSH descriptors whose meaning is more specific than "Ghrelin".
This graph shows the total number of publications written about "Ghrelin" by people in this website by year, and whether "Ghrelin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2015 | 4 | 0 | 4 | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ghrelin" by people in Profiles.
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Bianchi E, Boekelheide K, Sigman M, Lamb DJ, Hall SJ, Hwang K. Ghrelin Inhibits Post-Operative Adhesions via Blockage of the TGF-? Signaling Pathway. PLoS One. 2016; 11(4):e0153968.
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Bianchi E, Boekelheide K, Sigman M, Lamb DJ, Hall SJ, Hwang K. Ghrelin ameliorates adhesions in a postsurgical mouse model. J Surg Res. 2016 Mar; 201(1):226-34.
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Garcia JM, Chen JA, Guillory B, Donehower LA, Smith RG, Lamb DJ. Ghrelin Prevents Cisplatin-Induced Testicular Damage by Facilitating Repair of DNA Double Strand Breaks Through Activation of p53 in Mice. Biol Reprod. 2015 Jul; 93(1):24.
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Hijaz NM, Friesen CA, Schurman JV, Pearce RE, Abdel-Rahman SM. Plasma ghrelin and liquid gastric emptying in children with functional dyspepsia consistent with post-prandial distress syndrome. Neurogastroenterol Motil. 2015 Aug; 27(8):1120-6.
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Whirledge SD, Garcia JM, Smith RG, Lamb DJ. Ghrelin partially protects against cisplatin-induced male murine gonadal toxicity in a GHSR-1a-dependent manner. Biol Reprod. 2015 Mar; 92(3):76.
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Talebizadeh Z, Kibiryeva N, Bittel DC, Butler MG. Ghrelin, peptide YY and their receptors: gene expression in brain from subjects with and without Prader-Willi syndrome. Int J Mol Med. 2005 Apr; 15(4):707-11.
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Butler MG, Bittel DC, Talebizadeh Z. Plasma peptide YY and ghrelin levels in infants and children with Prader-Willi syndrome. J Pediatr Endocrinol Metab. 2004 Sep; 17(9):1177-84.
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