 2-Pyridinylmethylsulfinylbenzimidazoles
"2-Pyridinylmethylsulfinylbenzimidazoles" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that contain benzimidazole joined to a 2-methylpyridine via a sulfoxide linkage. Several of the compounds in this class are ANTI-ULCER AGENTS that act by inhibiting the POTASSIUM HYDROGEN ATPASE found in the PROTON PUMP of GASTRIC PARIETAL CELLS.
| Descriptor ID |
D053799
|
| MeSH Number(s) |
D02.886.640.074 D03.383.725.024 D03.438.103.034
|
| Concept/Terms |
2-Pyridinylmethylsulfinylbenzimidazoles- 2-Pyridinylmethylsulfinylbenzimidazoles
- 2 Pyridinylmethylsulfinylbenzimidazoles
- Benzimidazole Methylpyridine Sulfoxides
- Methylpyridine Sulfoxides, Benzimidazole
- Sulfoxides, Benzimidazole Methylpyridine
Timoprazole Derivatives- Timoprazole Derivatives
- 2-Pyridinylmethylsulfinyl-2-Benzimidazoles
- 2 Pyridinylmethylsulfinyl 2 Benzimidazoles
- Timoprazoles
- 2-Methylpyridine 2-Benzimidazole Sulfoxides
- 2 Methylpyridine 2 Benzimidazole Sulfoxides
- 2-Benzimidazole Sulfoxides, 2-Methylpyridine
- Sulfoxides, 2-Methylpyridine 2-Benzimidazole
|
Below are MeSH descriptors whose meaning is more general than "2-Pyridinylmethylsulfinylbenzimidazoles".
Below are MeSH descriptors whose meaning is more specific than "2-Pyridinylmethylsulfinylbenzimidazoles".
This graph shows the total number of publications written about "2-Pyridinylmethylsulfinylbenzimidazoles" by people in this website by year, and whether "2-Pyridinylmethylsulfinylbenzimidazoles" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "2-Pyridinylmethylsulfinylbenzimidazoles" by people in Profiles.
-
Feldman K, Kearns GL, Pearce RE, Abdel-Rahman SM, Steven Leeder J, Friesen A, Staggs VS, Gaedigk A, Weigel J, Shakhnovich V. Utility of the 13 C-pantoprazole breath test as a CYP2C19 phenotyping probe for children. Clin Transl Sci. 2022 05; 15(5):1155-1166.
-
Shakhnovich V, Brian Smith P, Guptill JT, James LP, Collier DN, Wu H, Livingston CE, Zhao J, Kearns GL, Cohen-Wolkowiez M. A Population-Based Pharmacokinetic Model Approach to Pantoprazole Dosing for Obese Children and Adolescents. Paediatr Drugs. 2018 Oct; 20(5):483-495.
-
Ogilvie BW, Yerino P, Kazmi F, Buckley DB, Rostami-Hodjegan A, Paris BL, Toren P, Parkinson A. The proton pump inhibitor, omeprazole, but not lansoprazole or pantoprazole, is a metabolism-dependent inhibitor of CYP2C19: implications for coadministration with clopidogrel. Drug Metab Dispos. 2011 Nov; 39(11):2020-33.
-
Kearns GL, Leeder JS, Gaedigk A. Impact of the CYP2C19*17 allele on the pharmacokinetics of omeprazole and pantoprazole in children: evidence for a differential effect. Drug Metab Dispos. 2010 Jun; 38(6):894-7.
-
Kearns GL, Blumer J, Schexnayder S, James LP, Adcock KG, Reed MD, Daniel JF, Gaedigk A, Paul J. Single-dose pharmacokinetics of oral and intravenous pantoprazole in children and adolescents. J Clin Pharmacol. 2008 Nov; 48(11):1356-65.
-
Conners GP, Hays DP. Emergency department drug orders: does drug storage location make a difference? Ann Emerg Med. 2007 Oct; 50(4):414-8.
-
Pearce RE, Rodrigues AD, Goldstein JA, Parkinson A. Identification of the human P450 enzymes involved in lansoprazole metabolism. J Pharmacol Exp Ther. 1996 May; 277(2):805-16.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|