X Chromosome Inactivation
"X Chromosome Inactivation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dosage compensation process occurring at an early embryonic stage in mammalian development whereby, at random, one X CHROMOSOME of the pair is repressed in the somatic cells of females.
Descriptor ID |
D049951
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MeSH Number(s) |
G05.355.315.203.249.970
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Concept/Terms |
X Chromosome Inactivation- X Chromosome Inactivation
- Chromosome Inactivation, X
- Inactivation, X Chromosome
- Lyonization
- X-Inactivation
- X Inactivation
- Inactivation, X
- X Inactivations
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Below are MeSH descriptors whose meaning is more general than "X Chromosome Inactivation".
Below are MeSH descriptors whose meaning is more specific than "X Chromosome Inactivation".
This graph shows the total number of publications written about "X Chromosome Inactivation" by people in this website by year, and whether "X Chromosome Inactivation" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2013 | 1 | 0 | 1 | 2017 | 0 | 1 | 1 | 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "X Chromosome Inactivation" by people in Profiles.
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Winham SJ, Larson NB, Armasu SM, Fogarty ZC, Larson MC, McCauley BM, Wang C, Lawrenson K, Gayther S, Cunningham JM, Fridley BL, Goode EL. Molecular signatures of X chromosome inactivation and associations with clinical outcomes in epithelial ovarian cancer. Hum Mol Genet. 2019 04 15; 28(8):1331-1342.
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Larson NB, Fogarty ZC, Larson MC, Kalli KR, Lawrenson K, Gayther S, Fridley BL, Goode EL, Winham SJ. An integrative approach to assess X-chromosome inactivation using allele-specific expression with applications to epithelial ovarian cancer. Genet Epidemiol. 2017 12; 41(8):898-914.
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Cotton AM, Ge B, Light N, Adoue V, Pastinen T, Brown CJ. Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome. Genome Biol. 2013 Nov 01; 14(11):R122.
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Bittel DC, Theodoro MF, Kibiryeva N, Fischer W, Talebizadeh Z, Butler MG. Comparison of X-chromosome inactivation patterns in multiple tissues from human females. J Med Genet. 2008 May; 45(5):309-13.
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Butler MG, Theodoro MF, Bittel DC, Kuipers PJ, Driscoll DJ, Talebizadeh Z. X-chromosome inactivation patterns in females with Prader-Willi syndrome. Am J Med Genet A. 2007 Mar 01; 143A(5):469-75.
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Talebizadeh Z, Bittel DC, Veatch OJ, Kibiryeva N, Butler MG. Brief report: non-random X chromosome inactivation in females with autism. J Autism Dev Disord. 2005 Oct; 35(5):675-81.
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