PPAR alpha
"PPAR alpha" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear transcription factor. Heterodimerization with RETINOID X RECEPTOR GAMMA is important to metabolism of LIPIDS. It is the target of FIBRATES to control HYPERLIPIDEMIAS.
| Descriptor ID |
D047493
|
| MeSH Number(s) |
D12.776.826.239.500
|
| Concept/Terms |
PPAR alpha- PPAR alpha
- Peroxisome Proliferator-Activated Receptor alpha
- Peroxisome Proliferator Activated Receptor alpha
- PPARalpha
|
Below are MeSH descriptors whose meaning is more general than "PPAR alpha".
Below are MeSH descriptors whose meaning is more specific than "PPAR alpha".
This graph shows the total number of publications written about "PPAR alpha" by people in this website by year, and whether "PPAR alpha" was a major or minor topic of these publications.
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Below are the most recent publications written about "PPAR alpha" by people in Profiles.
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Zhang Y, Lickteig AJ, Csanaky IL, Klaassen CD. Editor's Highlight: Clofibrate Decreases Bile Acids in Livers of Male Mice by Increasing Biliary Bile Acid Excretion in a PPARa-Dependent Manner. Toxicol Sci. 2017 Dec 01; 160(2):351-360.
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Zhang Y, Lickteig AJ, Csanaky IL, Klaassen CD. Activation of PPARa decreases bile acids in livers of female mice while maintaining bile flow and biliary bile acid excretion. Toxicol Appl Pharmacol. 2018 01 01; 338:112-123.