 Carboxylesterase
"Carboxylesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Carboxylesterase is a serine-dependent esterase with wide substrate specificity. The enzyme is involved in the detoxification of XENOBIOTICS and the activation of ester and of amide PRODRUGS.
| Descriptor ID |
D043182
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| MeSH Number(s) |
D08.811.277.352.100.100
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| Concept/Terms |
Carboxylesterase- Carboxylesterase
- Isocarboxazid amidase
- amidase, Isocarboxazid
- Non-specific Esterase
- Esterase, Non-specific
- Non specific Esterase
- Nonspecific Esterase
- Esterase, Nonspecific
- Procaine Esterase
- Esterase, Procaine
- Ali-esterase
- Ali esterase
- B-esterase
- B esterase
- CAP-hydrolyzing Enzyme
- CAP hydrolyzing Enzyme
- Enzyme, CAP-hydrolyzing
- Capsaicin-Hydrolyzing Enzyme
- Capsaicin Hydrolyzing Enzyme
- Enzyme, Capsaicin-Hydrolyzing
- Carboxyesterase
- Carboxylate Esterase
- Esterase, Carboxylate
- Carboxylester Lipase
- Lipase, Carboxylester
- Carboxylesterase B
- Carboxylic Ester Hydrolase
- Ester Hydrolase, Carboxylic
- Hydrolase, Carboxylic Ester
- Naproxen Esterase
- Esterase, Naproxen
- Non-specific Carboxylesterase
- Carboxylesterase, Non-specific
- Non specific Carboxylesterase
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Below are MeSH descriptors whose meaning is more general than "Carboxylesterase".
Below are MeSH descriptors whose meaning is more specific than "Carboxylesterase".
This graph shows the total number of publications written about "Carboxylesterase" by people in this website by year, and whether "Carboxylesterase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Carboxylesterase" by people in Profiles.
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Boberg M, Vrana M, Mehrotra A, Pearce RE, Gaedigk A, Bhatt DK, Leeder JS, Prasad B. Age-Dependent Absolute Abundance of Hepatic Carboxylesterases (CES1 and CES2) by LC-MS/MS Proteomics: Application to PBPK Modeling of Oseltamivir In Vivo Pharmacokinetics in Infants. Drug Metab Dispos. 2017 02; 45(2):216-223.
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Yang D, Pearce RE, Wang X, Gaedigk R, Wan YJ, Yan B. Human carboxylesterases HCE1 and HCE2: ontogenic expression, inter-individual variability and differential hydrolysis of oseltamivir, aspirin, deltamethrin and permethrin. Biochem Pharmacol. 2009 Jan 15; 77(2):238-47.
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