A disease that results from a congenital defect in ELECTRON TRANSPORT COMPLEX IV. Defects in ELECTRON TRANSPORT COMPLEX IV can be caused by mutations in the SURF1, SCO2, COX10, or SCO1 genes. ELECTRON TRANSPORT COMPLEX IV deficiency caused by mutation in SURF1 manifests itself as LEIGH DISEASE; that caused by mutation in SCO2 as fatal infantile cardioencephalomyopathy; that caused by mutation in COX10 as tubulopathy and leukodystrophy; and that caused by mutation in SCO1 as early-onset hepatic failure and neurologic disorder. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim, MIM#220110, May 17, 2001)

Descriptor ID	D030401
MeSH Number(s)	C16.320.565.240 C18.452.660.195
Concept/Terms	Cytochrome-c Oxidase Deficiency Cytochrome-c Oxidase Deficiency Cytochrome-c Oxidase Deficiencies Deficiencies, Cytochrome-c Oxidase Oxidase Deficiencies, Cytochrome-c Oxidase Deficiency, Cytochrome-c Cytochrome C Oxidase Deficiency Complex IV Deficiency Complex IV Deficiencies Deficiencies, Complex IV Deficiency, Complex IV Deficiency, Cytochrome-c Oxidase Deficiency, Cytochrome c Oxidase Mitochondrial Complex IV Deficiency Cox Deficiency Cox Deficiencies Deficiencies, Cox Deficiency, Cox Cytochrome Oxidase Deficiency Cytochrome Oxidase Deficiencies Deficiencies, Cytochrome Oxidase Deficiency, Cytochrome Oxidase Oxidase Deficiencies, Cytochrome Oxidase Deficiency, Cytochrome

Below are MeSH descriptors whose meaning is more general than "Cytochrome-c Oxidase Deficiency".

Below are MeSH descriptors whose meaning is related to "Cytochrome-c Oxidase Deficiency".

Below are MeSH descriptors whose meaning is more specific than "Cytochrome-c Oxidase Deficiency".