A maternally linked genetic disorder that presents in mid-life as acute or subacute central vision loss leading to central scotoma and blindness. The disease has been associated with missense mutations in the mtDNA, in genes for Complex I, III, and IV polypeptides, that can act autonomously or in association with each other to cause the disease. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/Omim/, MIM#535000 (April 17, 2001))

Descriptor ID	D029242
MeSH Number(s)	C10.292.700.225.500.400 C10.574.500.662.400 C11.270.564.400 C11.640.451.451.400 C16.320.290.564.400 C16.320.400.630.400 C18.452.660.670
Concept/Terms	Optic Atrophy, Hereditary, Leber Optic Atrophy, Hereditary, Leber Leber Hereditary Optic Atrophy Leber Hereditary Optic Neuropathy Leber Optic Atrophy Optic Atrophy, Leber Leber Optic Atrophy and Dystonia Leber's Disease Disease, Leber's Diseases, Leber's Leber Disease Leber's Diseases Lebers Disease Leber's Hereditary Optic Neuropathy Leber's Optic Atrophy Leber's Optic Neuropathy Leber Optic Neuropathy Lebers Optic Neuropathy Neuropathy, Leber's Optic Optic Neuropathy, Leber's Optic Atrophy, Leber Type Optic Atrophy, Leber, Hereditary Hereditary Optic Neuroretinopathy Hereditary Optic Neuroretinopathies Neuroretinopathies, Hereditary Optic Neuroretinopathy, Hereditary Optic Optic Neuroretinopathies, Hereditary Optic Neuroretinopathy, Hereditary Leber's Hereditary Optic Atrophy

Below are MeSH descriptors whose meaning is more general than "Optic Atrophy, Hereditary, Leber".

Below are MeSH descriptors whose meaning is related to "Optic Atrophy, Hereditary, Leber".

Below are MeSH descriptors whose meaning is more specific than "Optic Atrophy, Hereditary, Leber".